Can Down Syndrome Be Detected Before Birth? 

simran suri 

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Down syndrome, also known as trisomy 21, is a genetic condition caused by the presence of an extra copy of chromosome 21. This additional genetic material affects the development of the body and brain

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Down syndrome can be detected before birth through various prenatal screening and diagnostic tests. Here are some common methods used to detect Down syndrome before birth:

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First-Trimester Screening

This screening typically occurs between 11 and 14 weeks of pregnancy and involves a combination of maternal blood tests and ultrasound imaging.

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Cell-Free DNA Testing (cfDNA)

Also known as noninvasive prenatal testing (NIPT), this test analyzes fragments of fetal DNA circulating in the mother's blood. It can screen for chromosomal abnormalities, with high accuracy as early as 10 weeks of pregnancy.

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Second-Trimester Screening

This screening, also known as quad screening or multiple marker screening, is typically performed between 15 and 20 weeks of pregnancy. It involves measuring levels of certain hormones in the mother's blood to assess the risk of Down syndrome.

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Diagnostic Testing

If prenatal screening tests indicate an increased risk of Down syndrome, diagnostic tests can be performed to confirm the diagnosis. Tests such as chorionic villus sampling (CVS) and amniocentesis can be done. 

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Please Note 

Diagnostic testing carries a small risk of miscarriage and is typically offered to women with abnormal screening results or those seeking definitive information about their baby's condition.

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Consult a doctor for more information on Down Syndrome to ensure you make informed decisions about your health.

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