Written by: Mantasha
Why do some people shed kilos more effectively through exercise than others, even though regular physical activity is key to maintaining a healthy weight?
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Recent research from Kobe University in japan reveals that the answer might lie in a specific protein called PGC-1α. This protein plays a crucial role in how our bodies respond to exercise and regulate metabolism.
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Here’s a simplified breakdown:
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PGC-1α is a protein that regulates energy metabolism by boosting mitochondria production, fat burning, and energy use. It becomes more active during exercise, helping muscles burn more calories and support weight loss.
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There are different forms of PGC-1α. The "b" and "c" versions are particularly effective and increase significantly during exercise.
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Studies on mice and humans show that those without the "b" and "c" forms of PGC-1α burn less fat during workouts and might even gain weight, even with normal food intake.
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Understanding this could lead to new weight loss medications that mimic the effects of exercise or improve energy expenditure.
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While exercise is crucial, diet plays a bigger role in weight loss. Good exercise habits combined with a healthy diet are the most effective approach.
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In summary, how well people lose weight through exercise can depend on their specific versions of the PGC-1α protein.
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