Metadol 50mg/400mg Tablet is a combination medicine used in the treatment of pain due to muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.
Metadol 50mg/400mg Tablet is best taken in an empty stomach. You should take it regularly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.
Some of the common side effects on of this medicine includes nausea, vomiting, stomach pain, heartburn, diarrhea, sleepiness, and loss of appetite. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.
The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, and liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using the medicine.
Uses of Metadol Tablet
Treatment of Pain due to muscle spasm
Benefits of Metadol Tablet
In Treatment of Pain due to muscle spasm
Metadol 50mg/400mg Tablet is a combination medicine that contains a painkiller as well as a muscle relaxant. It is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain. Take Metadol 50mg/400mg Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Metadol Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metadol
Nausea
Vomiting
Stomach pain/epigastric pain
Heartburn
Diarrhea
Sleepiness
Loss of appetite
How to use Metadol Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metadol 50mg/400mg Tablet is to be taken empty stomach.
How Metadol Tablet works
Metadol 50mg/400mg Tablet is a combination of two medicines: Diclofenac and Metaxalone, which relieves pain and relaxes the muscles.Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Metaxalone is a muscle relaxant. It works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm. It relieves pain and improves the movement of muscles.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Metadol 50mg/400mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Metadol 50mg/400mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Metadol 50mg/400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Metadol 50mg/400mg Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Metadol 50mg/400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metadol 50mg/400mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Metadol 50mg/400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Metadol 50mg/400mg Tablet may be needed. Please consult your doctor. Regular monitoring of liver function tests is recommended in patients with liver disease if this medicine is to be taken for a long time.
What if you forget to take Metadol Tablet?
If you miss a dose of Metadol 50mg/400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
sir/madam i have pain in my testical(in left side) it slept at 4am. when I woke up it was paining since 2 days it may be due to cold and there is no swelling. may be little bit.
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. Your pain may be due to cold spasm or tortion. If pain persist please visit surgeon and examined.
When doing exercise got ache in the position of scapula L & spine. Take CALPOL T . But now I feel twinge at left arm as if vein is obstructed when I bent and move.
Dr. Rohit Chakor
Orthopaedics
Muscle spasm is the reason. Do Xray to rule out spine problem
I've got muscle spasm in back due to heavy weight lifting and this excruciating pain is unbearable . I'm unable to change my body posture or can't walk due to pain. I'm lying all the time and it just happened last night.
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Plz you don't move your body and no any exercise done for fifteen days absolute bed rest
Metadol 50mg/400mg Tablet is a combination of two medicines: Diclofenac and Metaxalone. This combination helps to relieve muscle pain. It works by relaxing muscles by acting on central nervous system and lowering chemical substance in the body that causes pain and inflammation.
Can I stop taking Metadol 50mg/400mg Tablet when my pain is relieved?
Metadol 50mg/400mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Metadol 50mg/400mg Tablet should be continued if your doctor has advised you to do so.
Can the use of Metadol 50mg/400mg Tablet cause nausea and vomiting?
Yes, the use of Metadol 50mg/400mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids. Talk to your doctor if vomiting persists and you notice signs of dehydration like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.
Can the use of Metadol 50mg/400mg Tablet cause dizziness?
Yes, the use of Metadol 50mg/400mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
Are there any specific contraindications associated with the use of Metadol 50mg/400mg Tablet?
The use of Metadol 50mg/400mg Tablet is considered to be harmful for patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients who have active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, or any underlying liver or kidney disease.
Can the use of Metadol 50mg/400mg Tablet cause damage to kidneys?
Yes, the long-term use of Metadol 50mg/400mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body which leads to kidney damage on long-term use. Use of painkillers is not recommended in patients with underlying kidney disease.
Can I take a higher than the recommended dose of this medicine?
No, taking a higher than the recommended dose of Metadol 50mg/400mg Tablet can lead to increased chances of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
What is the recommended storage condition for Metadol 50mg/400mg Tablet?
Keep this medication in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
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Metaxalone [Product Label]. Bristol, TN: King Pharmaceuticals, Inc.; 2008. [Accessed 16 Sep. 2024] (online) Available from:
Diclofenac sodium [Prescribing Information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2009. [Accessed 16 Sep. 2024] (online) Available from:
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