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Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine
INFORMATION ABOUT CAFFEINE + CETIRIZINE + NIMESULIDE + PARACETAMOL + PHENYLEPHRINE
Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine Uses
Caffeine+Cetirizine+Nimesulide+Paracetamol+Phenylephrine is used in the treatment of common cold.
How Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine works
Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine is a combination medicine that helps relieve symptoms of the common cold such as headache, fever, nasal congestion, runny nose, and body pain. It works through the combined action of its ingredients. Paracetamol and nimesulide reduce fever and relieve pain by blocking the production of certain chemicals (prostaglandins) responsible for inflammation. Phenylephrine acts as a nasal decongestant by narrowing the blood vessels in the nasal passages, which helps ease breathing. Cetirizine is an antihistamine that reduces allergy symptoms like sneezing, runny nose, and watery eyes. Caffeine helps enhance alertness and may also increase the pain-relieving effect of paracetamol, helping you feel more active and less fatigued during illness.
Common side effects of Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common
Nausea, Diarrhea, Vomiting, Dryness in mouth, Insomnia (difficulty in sleeping), Allergic reaction, Restlessness, Fatigue, Dizziness, Sleepiness, Increased liver enzymes, Headache
CONTENT DETAILS
Written By
Dr. Mayank
Pharm.D
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
29 Oct 2025 | 10:39 AM (UTC)
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Expert advice for Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine
  • Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine is prescribed to get relief from symptoms of common cold.
  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.
  • Inform your doctor if you are taking any other medications for cold.
  • Call your doctor if your symptoms have not improved within seven days of treatment or if you develop a fast, pounding, or uneven heartbeat, severe dizziness or anxiety, severe headache, fever, or rash.
  • Inform your doctor if you are taking any antidepressants.
Frequently asked questions for Caffeine + Cetirizine + Nimesulide + Paracetamol + Phenylephrine
Caffeine+Cetirizine+Nimesulide+Paracetamol+Phenylephrine is a combination of five medicines: Caffeine, Cetirizine, Nimesulide, Paracetamol and Phenylephrine. This combination is helpful in relieving the symptoms of cold. These symptoms include body ache, headache, fatigue, fever, watery eyes, sneezing, cough, sore throat, runny and stuffy nose.
No, it is not advisable to breastfeed while using Caffeine+Cetirizine+Nimesulide+Paracetamol+Phenylephrine. This medicine contains cetirizine, an antihistamine, which can pass into the breast milk and may harm the baby. Inform your doctor that you are breastfeeding if you are advised to take this medicine.
Caffeine+Cetirizine+Nimesulide+Paracetamol+Phenylephrine contains Paracetamol and Nimesulide. These medicines are known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease. Contact your doctor immediately if you notice any early signs and symptoms of liver damage. These symptoms may include fever, rash, loss of appetite, nausea, vomiting, fatigue, stomach pain, dark urine, yellow skin or eyes and abnormal liver enzymes.
Caffeine+Cetirizine+Nimesulide+Paracetamol+Phenylephrine contains caffeine. So, it is preferable to avoid medicines or food that also contain caffeine. Foods like coffee, tea, cola drinks and chocolate should be avoided as they may add to your total caffeine intake. Increased caffeine intake can cause difficulty in sleeping, you may experience tremors and/or may have chest discomfort. Also, avoid drinking alcohol (beer, wine, etc) while taking this medicine.
Yes, Caffeine+Cetirizine+Nimesulide+Paracetamol+Phenylephrine may make you feel drowsy or may cause you to fall asleep during your daily activities. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
Serious side effects with Caffeine+Cetirizine+Nimesulide+Paracetamol+Phenylephrine are uncommon and rare. Tell your doctor as soon as possible if you notice allergic reactions, skin rash or peeling, mouth ulcers, breathing problems, unexplained bleeding, recurrent fevers or infections, vision disturbances, fast or irregular heartbeat. These side effects are uncommon but may be serious and may need urgent medical attention.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.