Information about Cefoperazone

Cefoperazone Uses

Cefoperazone is used in the treatment of bacterial infections.

How Cefoperazone works

Cefoperazone is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Common side effects of Cefoperazone

Diarrhea, Itching, Decreased hemoglobin, Decreased hematocrit level, Decreased white blood cell count (neutrophils), Positive Coombs test, Low blood platelets, Increased white blood cell count (eosinophils), Injection site phlebitis, Increased aspartate aminotransferase, Increased alanine aminotransferase, Increased alkaline phosphatase level in blood, Jaundice, Urticaria, Maculopapular rash
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Written By
BDS
Reviewed By
MBA, MD Pharmacology
Last updated
28 Oct 2022 | 11:44 AM (UTC)

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Expert advice for Cefoperazone

  • Your doctor has prescribed Cefoperazone to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
  • Discontinue Cefoperazone and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
  • Take it with food to avoid an upset stomach.
  • Avoid consuming alcohol while taking Cefoperazone as it may cause increased side effects.

Frequently asked questions for Cefoperazone

Cefoperazone

Q. Is Cefoperazone effective?

Cefoperazone is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Cefoperazone too early, the symptoms may return or worsen.

Q. Is Cefoperazone bactericidal or bacteriostatic?

Cefoperazone is primarily bactericidal(one which kills the causative organisms) but it may be bacteriostatic (one which slows down the growth of bacteria) also. Its activity depends on the organism, tissue penetration, dosage, and rate of organism multiplication.

Q. How does Cefoperazone act?

Cefoperazone acts by adhering to the proteins synthesized by the bacteria, thereby inhibiting the organisms to develop their protective covering known as cell wall. This kills the bacteria.

Q. Is Cefoperazone bad for the kidneys?

No, Cefoperazone is not bad for the kidneys when given alone, but when given along with aminoglycosides (gentamicin, tobramycin) or other cephalosporins antibiotics, it may increase kidney damage. Therefore, it is advised to take this medicine only if prescribed by your doctor.

Q. Can the use of Cefoperazone cause diarrhea?

Yes, the use of Cefoperazone can cause diarrhea. Cefoperazone is an antibiotic which kills the harmful bacteria but can also affect the helpful bacteria in your stomach or intestine and cause diarrhea. If diarrhea persists, talk to your doctor about it.

Q. How long does Cefoperazone take to work?

Usually, Cefoperazone starts working soon after you take it. However, it may take some days to kill all the harmful bacteria and relieve your symptoms completely.

Q. What if I do not get better after using Cefoperazone?

Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your doctor if the symptoms get worse while using this medicine.

Q. What if I forget to take a dose of Cefoperazone?

If you forget a dose of Cefoperazone, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

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