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Apolipoprotein - B

Also known as Apolipoprotein B-100

₹409

You need to provide

Blood

This test is for

Male, Female

Test Preparation

No special preparation is required.

Understanding Apolipoprotein - B

What is Apolipoprotein - B?

An Apolipoprotein - B test measures the amount of apolipoprotein B in your blood. This test is performed to provide valuable insights into an individual’s heart health by evaluating your risk of developing cardiovascular disease (CVD) such as heart attack and stroke.

Apolipoprotein B, known as Apo-B, is a critical protein involved in the transport and metabolism of fats in the blood. It is primarily associated with low-density lipoprotein (LDL), also known as “bad” cholesterol. Elevated levels of Apo-B are associated with an increased risk of atherosclerosis, the process involving the buildup of plaque (harmful fats, cholesterol, and other substances) in the arteries (blood vessels that carry blood). This buildup can lead to heart attacks, strokes, and other cardiovascular diseases. Therefore, understanding your Apo-B levels can be an important part of managing your overall heart health.

An Apolipoprotein - B is especially useful when standard cholesterol tests, such as LDL cholesterol levels, may not provide a complete picture of cardiovascular risk. Your doctor may advise this test if you experience symptoms suggestive of heart disease or cardiovascular problems, such as chest pain, shortness of breath, palpitations, or other cardiac symptoms. Apolipoprotein - B test is also recommended if you have risk factors such as high blood pressure, high cholesterol, obesity, diabetes, smoking, or a family history of heart disease or chronic conditions like diabetes, high blood pressure, etc. This test is also recommended to monitor the effectiveness of ongoing treatment in individuals already diagnosed with cardiovascular disease. Additionally, an Apolipoprotein - B also helps diagnose a rare inherited deficiency of Apolipoprotein B.

No fasting is required for this test. You can eat and drink normally as per your routine. It is important to inform your doctor about any heart medications or supplements you are taking, as some could impact the test results. Always seek your doctor’s advice before altering any medication routine.

Lab test results may vary across different laboratories. Discuss your symptoms and specific test results with your doctor to help them correlate your clinical and laboratory findings. Based on your test results, the doctor may recommend a treatment plan and lifestyle adjustments. These can include dietary changes, weight loss, medication, and discontinuation of certain medications.

What is Apolipoprotein - B used for?

An Apolipoprotein - B test is done:

To identify individuals at risk for developing cardiovascular problems.
In individuals with risk factors like family history, obesity, diabetes, high blood pressure, and prior heart attack or stroke.
When an individual experiences symptoms suggestive of heart disease or cardiovascular problems such as chest pain, shortness of breath, palpitations, etc.
To help doctors formulate treatment plans according to individual patient needs.
To monitor the effectiveness of ongoing treatments in individuals already diagnosed with heart disease, or to monitor the effect of lifestyle modifications in those identified as “high-risk” individuals for developing future heart-related ailments.

What does Apolipoprotein - B measure?

The Apolipoprotein B test is used to evaluate the level of Apolipoprotein B in your blood. It is a type of protein that aids in the transportation of fat and cholesterol throughout the body. Apo B serves as the primary protein component of lipoproteins such as very low-density lipoprotein (VLDL), low-density lipoprotein (LDL), and chylomicrons. It binds to LDL or “bad” cholesterol, causing plaque accumulation in the blood vessels. This can lead to the development and progression of cardiovascular disease that can be life-threatening if left untreated.

Interpreting Apolipoprotein - B results

Interpretations

Apolipoprotein A1 is the primary protein associated with HDL Cholesterol. It shows a protective function against heart disease. Increased levels are associated with reduced risk of cardiovascular disease.

Apolipoprotein B is the primary protein associated with LDL Cholesterol and plaque formation. Increased levels are associated with increased risk of heart disease.

The ratio of these two correlates with the risk of cardiovascular disease.

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Apolipoprotein - B

Frequently Asked Questions about Apolipoprotein - B

Q. Why is the Apolipoprotein - B test done?

The Apolipoprotein - B test is done to evaluate the levels of Apo-B in your blood. It helps in assessing your risk for developing cardiovascular diseases such as heart attack, atherosclerosis, stroke, etc.

Q. Do I need to fast before taking the Apolipoprotein - B test?

No fasting is required for this test. You can schedule it at your convenience without avoiding food or water beforehand.

Q. How frequently should I undergo an Apolipoprotein - B test?

The frequency of Apolipoprotein - B test depends on your individual health factors such as age, family history of heart ailments, lifestyle habits, and existing health conditions like diabetes, high blood pressure, etc. It is best to discuss with your doctor to decide how often you need this test based on your individual health needs and risks.

Q. What factors can affect the result of the Apolipoprotein - B test?

The factors that can affect Apolipoprotein - B test results include age, gender, genetic factors or family history of heart disease, diet, smoking, alcohol consumption, and the use of certain medications such as androgens, beta-blockers, diuretics, or progestins (synthetic progesterones).

Q. What can be the possible causes that lead to a drop in the levels of Apo-B?

Apo-B levels in the body decrease due to various factors including liver disease, hyperthyroidism, use of certain medicines, malnutrition, genetic conditions, etc.

Q. What does it mean if my Apo-B levels are high?

High levels of Apo-B indicate high LDL (bad cholesterol) levels in the blood, which can lead to the buildup of plaque in the arteries, known as atherosclerosis. This increases the risk of developing heart disease and stroke.

Q. What is atherosclerosis?

Atherosclerosis is a condition where the formation of plaque (buildup of cholesterol, and other harmful substances) takes place inside the arteries, which can cause heart attack or stroke.

Q. How can I lower my Apo B levels?

Discuss your test results with your doctor to get the best possible advice which may include medications too, if required. However, adopting some healthy lifestyle habits such as a heart-healthy diet, engaging in regular exercise, maintaining a healthy weight, quitting smoking, limiting alcohol consumption, and managing stress may help you lower your Apo B levels.

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