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Understanding the Test
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Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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PAP Smear

This test is for
Female
Test Preparation
  1. Provide brief clinical history/ doctor's prescription at the time of sample collection. A visit to the lab is mandatory for sample collection. Refrain from sexual activity for 2 to 5 days before the sample collection.

Understanding PAP Smear


What is PAP Smear?

The PAP Smear test is a routine, painless screening procedure used to detect abnormal cells in the cervix, which could indicate potential issues such as cervical cancer or precancerous conditions. By collecting a sample of cells from the cervix, this test helps in the early identification and management of cervical health issues, guiding appropriate treatment and prevention strategies.

According to the World Health Organization (WHO), cervical cancer ranks as the fourth most common cancer among women worldwide. It is primarily caused by the Human papillomavirus (HPV), a prevalent sexually transmitted infection that can affect the skin, genital area, and throat. Most sexually active individuals will contract HPV at some point, often without showing any symptoms. Typically, the immune system clears the virus from the body. However, a persistent infection with high-risk HPV can lead to abnormal cell changes that may eventually develop into cancer. The Pap smear is crucial in detecting these early changes before they progress to cancer, making it a vital tool in preventive healthcare for women.

The PAP Smear test is generally recommended for women between 25 and 65 years old and is usually done every three to five years, as per the doctor's recommendation. It is also done during a routine pelvic exam or for people with higher risk factors such as  those with a history of HPV infection, or family history of cervical cancer. It is often combined with HPV testing which is more effective in detecting early changes of cancer since HPV infection is one of the major risk factors linked to cervical cancer. Regular screening is essential as it helps identify abnormal cell changes early, enabling prompt treatment and significantly reducing the risk of developing cervical cancer.

To perform a Pap Smear, a healthcare provider first conducts a pelvic exam to access the cervix. Using a speculum, the cervix is gently opened to allow for clear visibility. A small brush or spatula is then used to collect a sample of cells from the cervix. This sample is sent to a laboratory where it is examined under a microscope for any unusual changes. 

You need to provide a brief clinical history or a doctor’s prescription when you go for sample collection. It's important to avoid sexual activity for 2 to 5 days before the test. It is also advised to refrain using tampons or vaginal medicines for 2 days before the test. These precautions help prevent interference with the test and ensure a clear, and uncontaminated sample is collected.

Interpretation of test results requires expert guidance, therefore do not self-medicate solely based on these test results and always consult the doctor for proper understanding of your test results. The pap smear test helps doctors make informed decisions about further treatment or lifestyle recommendations. Additionally, preventing HPV through vaccination is a key measure in reducing the risk of cervical cancer and other related conditions, complementing the insights gained from pap smear results.

What is PAP Smear used for?

The PAP Smear test is done: 

  • To screen for abnormal cells in the cervix that may indicate cervical cancer or precancerous conditions.
  • In  women with symptoms of cervical cancer or have early-stage cervical cancer.
  • In women with a history of abnormal Pap results or HPV infections.
  • To screen for cervical cancer in high risk individuals such as having an HIV infection, weakened immune system, family history of cervical cancer.
  • To monitor the health of the cervix in women who have had previous abnormalities detected.

What does PAP Smear measure?

The PAP Smear test measures the presence of abnormal cells in the cervix by examining a sample of cervical cells under a microscope. This test is primarily used to detect precancerous changes or early signs of cervical cancer. The collected cells are analyzed to identify any deviations from normal cell structures, which could indicate potential issues such as dysplasia or malignancy. By assessing these cellular abnormalities, the Pap Smear helps in early diagnosis and facilitates timely intervention, enabling effective treatment and prevention of cervical cancer.

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