Test Detail
Understanding the Test
Test Measures
References
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Content created by
Written by
Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
Reviewed by
Dr. Ashish Ranjan
MBBS, MD (Pharmacology)
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Tomato

You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Tomato


What is Tomato?

The Tomato test is a specialized allergy test designed to measure specific IgE antibodies in response to tomato proteins. This test aids in identifying tomato and tomato-based food allergies and helps doctors formulate effective care plans to manage symptoms and prevent reactions.

Tomatoes are a key ingredient in cuisines worldwide. They are rich in essential nutrients like vitamins A, C, and K and antioxidants, offering numerous health benefits. However, for some individuals, consuming tomatoes may trigger allergic reactions, which can lead to symptoms like gastrointestinal issues, skin rashes, or hives. The Tomato is a vital diagnostic test that helps determine whether someone has a tomato allergy. By analyzing the presence of immunoglobulin E (IgE) antibodies specific to tomato proteins, this test helps confirm if the immune system is reacting to tomatoes as a harmful allergen, triggering allergic symptoms.

The Tomato test is recommended for individuals who experience symptoms such as swelling, itching, or discomfort in the mouth or throat, as well as skin rashes, abdominal pain, nausea, or diarrhea after consuming tomatoes or tomato-based products. It is especially useful in diagnosing tomato allergies and distinguishing them from other conditions like oral allergy syndrome (OAS) or food intolerances. OAS occurs when certain raw fruits and vegetables, such as tomatoes, cause itching or swelling of the lips, mouth, or throat due to cross-reactivity between tomato proteins and pollen from plants like birch or grass. 

A positive result for tomato-specific IgE antibodies indicates an allergy to tomatoes, and it is generally recommended to avoid them to prevent allergic reactions. If the test result is negative, additional tests may be necessary to investigate other potential causes for the symptoms, such as food sensitivities or non-IgE-mediated reactions.

No special preparation is required for the Tomato. Inform the doctor about any medications (such as antihistamines) or supplements being taken, as they might influence the test results.

Lab test results can vary depending on the specific test kit used, as different methods and the quality of allergens used can affect the quantification of IgE. Therefore, these results are intended to be interpreted in conjunction with clinical symptoms. 

What is Tomato used for?

The Tomato test is done:

  • To confirm an allergy to tomatoes in individuals with a history of allergic reactions or symptoms triggered by consuming tomatoes.
  • To evaluate the cause of symptoms like abdominal pain, nausea, itching, swelling, or gastrointestinal discomfort that may be caused by tomato consumption.
  • To help formulate treatment plans that include dietary changes and medications aimed at managing allergic reactions.
  • To monitor the effectiveness of current tomato allergy treatments and adjust management strategies as needed.
  • To identify individuals at risk for developing food allergies, particularly those with a family history of allergic conditions.

What does Tomato measure?

The Tomato test measures the presence and levels of specific IgE antibodies against tomato proteins. This test helps determine whether an individual’s immune system is reacting to tomatoes, which is essential for diagnosing tomato allergies and differentiating them from other conditions like food intolerances or oral allergy syndrome.

The test is a highly precise and reliable method that measures IgE antibodies, providing valuable insights into the severity of the tomato allergic response and guiding further diagnostic and treatment decisions.

 

References

  1. Dougherty JM, Alsayouri K, Sadowski A. Allergy. [Updated 2023 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545237/ External Link
  2. Włodarczyk K, Smolińska B, Majak I. Tomato Allergy: The Characterization of the Selected Allergens and Antioxidants of Tomato (Solanum lycopersicum)-A Review. Antioxidants (Basel). 2022 Mar 28;11(4):644. https://pubmed.ncbi.nlm.nih.gov/35453329/ External Link
  3. Lopez CM, Yarrarapu SNS, Mendez MD. Food Allergies. [Updated 2023 Jul 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482187/ External Link
  4. Causes and prevention of food allergy [Internet]. NIH; 23 Mar. 2023. [Accessed 26 Nov. 2024]. Available from: https://www.niaid.nih.gov/diseases-conditions/food-allergy-causes-prevention External Link
  5. Allergens [Internet]. NIH; 07 Sep. 2022. [Accessed 26 Nov. 2024]. Available from: https://www.niehs.nih.gov/health/topics/agents/allergens/index.cfm External Link
  6. Portnoy JM. Appropriate allergy testing and interpretation. Mo Med. 2011 Sep-Oct;108(5):339-43. PMID: 22073491; PMCID: PMC6188374. [Accessed 26 Nov. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188374/ External Link
  7. Sinclair D, Peters SA. The predictive value of total serum IgE for a positive allergen-specific IgE result. J Clin Pathol. 2004 Sep;57(9):956-9. [Accessed 26 Nov. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770430/External Link
  8. IgE (Total) Allergy Test [Internet]. South Tees Hospitals NHS Foundation Trust; 27 Apr. 2022. [Accessed 26 Nov. 2024]. Available from: https://www.southtees.nhs.uk/services/pathology/tests/ige-total-allergy-test/External Link
  9. Abrams EM, Sicherer SH. Diagnosis and management of food allergy. CMAJ. 2016 Oct 18;188(15):1087-1093. [Accessed 26 Nov. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056872/ External Link
  10. Sussman G, Sussman A, Sussman D. Oral allergy syndrome. CMAJ. 2010 Aug 10;182(11):1210-1. [Accessed 26 Nov. 2024]. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2917934/ External Link

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