Acitrom 4 Tablet is an oral anticoagulant that helps prevent harmful blood clots in the legs, lungs, brain, and heart. It is used for deep vein thrombosis, pulmonary embolism, and stroke prevention.
Acitrom 4 Tablet should be taken as advised by the doctor. You may take it with or without food, but it is better to take it at a fixed time. This medicine should not be stopped abruptly without consulting the doctor. You should take this medicine regularly to get the most benefit, even if you feel fine. It prevents future harm.
The most common side effect of Acitrom 4 Tablet is bleeding. Let your doctor know immediately if you see a pinpoint rash or blood in your vomit, urine, or stool. If you are going under any surgery or dental treatment, you may need to stop this medicine for some time, but only after consulting with your doctor.
Before taking Acitrom 4 Tablet, you must inform the doctor if you are suffering from any kidney or liver disease or taking any medicine, including supplements and herbal products. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Acitrom 4 Tablet helps prevent and treat deep vein thrombosis (DVT) by thinning the blood and reducing the risk of harmful clots forming in the deep veins, typically in the legs. By improving blood flow and preventing clot-related complications like pulmonary embolism, it reduces leg pain, swelling, and discomfort, enhancing mobility and daily comfort. With regular use and monitoring, Acitrom 4 Tablet supports long-term vascular health, lowers the risk of recurrence, and helps individuals maintain an active, worry-free lifestyle.
In Treatment of Blood clots
Acitrom 4 Tablet is an oral anticoagulant that helps prevent and treat blood clots, reducing the risk of serious conditions like deep vein thrombosis (DVT), pulmonary embolism, heart attacks, and strokes. By thinning the blood and preventing clot formation, it ensures better circulation and lowers the risk of life-threatening complications. This helps maintain overall cardiovascular health, allowing individuals to stay active and free from the dangers of clot-related events. Regular monitoring ensures safe and effective use, promoting long-term well-being and a better quality of life.
Side effects of Acitrom Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Acitrom
Hemorrhage
How to use Acitrom Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Acitrom 4 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Acitrom Tablet works
Acitrom 4 Tablet works by slowing down the body's ability to form blood clots. It does this by blocking the action of vitamin K, which is essential for making clotting proteins in the liver. By reducing these clotting proteins, Acitrom 4 Tablet thins the blood, making it less likely for harmful clots to form.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Acitrom 4 Tablet.
Pregnancy
UNSAFE
Acitrom 4 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Acitrom 4 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
SAFE
Acitrom 4 Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Acitrom 4 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Acitrom 4 Tablet may be needed. Please consult your doctor. Use of Acitrom 4 Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Acitrom 4 Tablet should be used with caution in patients with liver disease. Dose adjustment of Acitrom 4 Tablet may be needed. Please consult your doctor. Use of Acitrom 4 Tablet is not recommended in patients with severe liver disease.
What if you forget to take Acitrom Tablet?
If you miss a dose of Acitrom 4 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Avoid making sudden major changes to your diet during treatment with this medicine.
Acitrom 4 Tablet increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects, or engaging in contact sports (e.g., football, wrestling).
Notify your doctor if you see blood in your vomit, urine, or stool (black, tarry stools or bright red blood).
Do not consume alcohol while taking Acitrom 4 Tablet, as this may increase its side effects.
If you are going to have a surgery or dental treatment, you may be asked to stop taking Acitrom 4 Tablet temporarily.
Do not discontinue use without consulting your doctor, as this may increase your chances of having another heart attack or stroke.
Your doctor may get regular blood tests done to make sure Acitrom 4 Tablet is working properly.
Fact Box
Chemical Class
4-hydroxycoumarin Derivative
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Vitamin K Antagonists
Interaction with drugs
Taking Acitrom with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.
Concurrent use may increas... More
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of severe bleeding.
Do not consume Acenocoumarol with Cilostazol. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Concurrent use may increase the risk of b... More
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.
Concurrent use may increas... More
If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.
Concurrent use may increas... More
Im PATIENT 32 male . i had CVT problems from 2005 onwards. I took acitrom for the past 11 years. After doctor took a blood test Genetic test ) told to stop actirom. within 14 days of stopping acitrom i got heart attack. angiogram done for me and find that , there is a clot in heart and its cleared by aggriblock medicine. Cholestrol are in normal level for me. Also a new problems find that, diabetes for me. one year before i took glucose test, all are in normal level. I want to know that, what are the foods i have to eat and which one i have to avoid? what are the things i have to follow for my future. Because i got married 2 years before ( nearly ) i have 10 kid now. So, i need your valuable suggestion. Kindly help me. Regards, PATIENT i have 10 months kid now. So, i need your valuable suggestion.
My son suffered from cortical sinus Venus thrombosis last year. He is taking acitrom 2 mg and clopilet 75. Last month I repeated venogram and it is cleared. So shall I stop taking the medicine
What were the side-effects while using Acitrom 4 Tablet?
Bleeding
60%
No Side Effec*
40%
*No Side Effect
How do you take Acitrom Tablet?
With food
52%
With or witho*
24%
Empty stomach
24%
*With or without food
Please rate Acitrom 4 Tablet on price
Expensive
52%
Not Expensive
27%
Average
21%
FAQs
How long do I need to take Acitrom 4 Tablet?
You should continue taking Acitrom 4 Tablet for as long as recommended by your doctor. Depending upon the condition you are being treated for, you may have to take it for several months or years or maybe for the rest of your life.
What should I avoid while taking Acitrom 4 Tablet?
You should avoid alcohol while taking Acitrom 4 Tablet as alcohol may interfere with working of Acitrom 4 Tablet. In addition to that, avoid cranberry juice or other cranberry products as there may be a risk of enhanced blood thinning. Avoid breastfeeding or getting pregnant as it may harm your child.
Do I need to stop Acitrom 4 Tablet if I have to undergo a surgery?
Depending on the type of surgery that is to be performed, your doctor will tell you whether to continue or stop Acitrom 4 Tablet. It will be decided by your doctor after weighing the risks and benefits of discontinuing Acitrom 4 Tablet.
Is Acitrom 4 Tablet same as warfarin?
Both Acitrom 4 Tablet and warfarin are blood thinners, but they have some differences. Warfarin has a more stable blood thinning effect.
How long does it take for Acitrom 4 Tablet to start working?
It takes a little longer for Acitrom 4 Tablet to start working. On an average, it may take 2-3 days for Acitrom 4 Tablet to show its blood-thinning effect. For these 2-3 days, heparin may be used and then discontinued.
What if I forget to take a dose?
If you forget to take a dose of Acitrom 4 Tablet, take it as soon as you remember. However, if it is time for your next dose then skip the missed dose. Do not double the dose and continue your normal schedule. Keep a diary or set a reminder, so that you do not forget it often.
What monitoring is required while taking Acitrom 4 Tablet?
The bleeding times should be carefully monitored from 2nd or 3rd dose of Acitrom 4 Tablet and till the clotting status is stabilized. Thereafter, the bleeding time can be monitored monthly. This frequency may be more in elderly.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-71.
Acenocoumarol [EMC SmPC]. Luxembourg: Merus Labs Luxco II S.à R.L.; 2025. [Accessed 03 May 2025] (online) Available from:
Castellano JM, Narayan RL, Vaishnava P, et al. Anticoagulation during pregnancy in patients with a prosthetic heart valve. Nat Rev Cardiol. 2012;9(7):415-24. [Accessed 14 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Acenocoumarol. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:
Acenocoumarol [Package Leaflet]. Madrid, Spain: Rovi Pharma Industrial Services, S.A.,; 2025. [Accessed 03 May 2025] (online) Available from:
Acenocoumarol [Prescribing Information]. Montreal, Quebec: Paladin Labs Inc.; 2009. [Accessed 03 May 2025] (online) Available from:
Country of origin: India Expires on or after: August, 2026
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