Aderef 400mg Tablet is a medicine used for the treatment of liver disease associated with reduced bile formation (intrahepatic cholestasis). It protects the liver cells from toxins and helps the liver to perform its normal functions.

Aderef 400mg Tablet may be taken with or without food. The dose will depend on what you are being treated for and your body weight. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.

The most common side effects are nausea, diarrhea, upset stomach, constipation, and dizziness. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough of water or fluids to stay hydrated in case of severe diarrhea and constipation.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.

Uses of Aderef Tablet

Treatment of Liver disease

Benefits of Aderef Tablet

In Treatment of Liver disease

Intrahepatic cholestasis is a type of liver disease that is associated with low bile formation. Aderef 400mg Tablet is used to treat this condition and may be used alone or with other medicines. It protects the liver cells from toxins and helps the liver to perform its normal functions. Once you start this treatment, it is likely that you will be taking it for a long time. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.

Side effects of Aderef Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aderef

Nausea
Diarrhea
Upset stomach
Constipation
Dizziness

How to use Aderef Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aderef 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Aderef Tablet works

Aderef 400mg Tablet protects the liver cells from toxins and helps the liver to perform its normal functions.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Aderef 400mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Aderef 400mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Aderef 400mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Aderef 400mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Aderef 400mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Aderef 400mg Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Aderef 400mg Tablet

₹64.9/Tablet

Heptral 400mg Tablet

Abbott

₹136.1/tablet

110% costlier

Cirrosam 400 Tablet

La Renon Healthcare Pvt Ltd

₹113.1/tablet

74% costlier

S-Methiwave 400 Tablet

Brainwave Healthcare Pvt Ltd

₹66.2/tablet

2% costlier

Viadali 400mg Tablet

Mylan Pharmaceuticals Private Limited

₹111.5/tablet

72% costlier

Olakino 400 Tablet

Ponoogun Healthcare Pvt Ltd

₹126.6/tablet

95% costlier

View all substitutes

Quick tips

It protects the liver cells from toxins and helps the liver to perform its normal functions.
Take it as per dose and duration suggested by your doctor.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Consult with your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

5'-deoxy-5'-thionucleosides Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotectives

Patient concerns

Fatty liver disease with enlarged liver

Dr. Aanchal Maheshwari

Ayurveda

Take cytozen capsule twice, lavanbhasksr churan half spoon twice

Liver disease due to fatty liver

Dr. Deepak Kumar Soni

Ayurveda

Hi kindly share your reports

FAQs

Q. What is Aderef 400mg Tablet?

Aderef 400mg Tablet is a natural substance found in cells, tissue, and body fluids. It is produced from methionine, an amino acid containing sulfur, and adenosine triphosphate (ATP). The nutritional supplement is harvested from yeast (fungus) cell cultures.

Q. What is Aderef 400mg Tablet used for?

Aderef 400mg Tablet has been studied extensively for depression, osteoarthritis, and depression. But, there is no conclusive evidence that it is helpful in these conditions.

Q. Who should not use Aderef 400mg Tablet?

Patients with bipolar disorder (an illness characterized by mood swings, from depression to mania) should not be given Aderef 400mg Tablet for depression as it can worsen symptoms of mania. Also, consult your doctor if you are pregnant or nursing mother, have Parkinson’s disease or if you are HIV-positive.

Q. What are the side effects of Aderef 400mg Tablet?

The side effects of Aderef 400mg Tablet are usually not very serious. These side effects include headache, nausea, and diarrhea. However, these effects are not very common.

Q. Is Aderef 400mg Tablet safe to use for long term?

Information on long term safety of Aderef 400mg Tablet is limited. There is one study in which patients took it for 2 years and no serious side effects were reported.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Medscape. Ademetionine. [Accessed 28 Mar. 2019] (online) Available from:
Drugs.com. Ademetionine. [Accessed 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Dec. 2019] (online) Available from:
Ademetionine [Product Label]. Ahmedabad, Gujarat: La Renon Healthcare Private Limited; 2022. [Accessed 09 Jun, 2023] (online) Available from:
Mount Sinai. S-adenosylmethionine. [Accessed 09 Jun, 2023] (online) Available from:

Marketer details

Name: Skyglow Pharmaceuticals Private Limited

Address: NO 22/10, ELANGO NAGAR 1st STREET VIRUGAMBAKKAM Chennai TN 600092 IN

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.