Adoxi 120mg Injection Combipack
Prescription Required
Product introduction
Adoxi 120mg Injection Combipack is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.
Adoxi 120mg Injection Combipack is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Adoxi 120mg Injection Combipack is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Adoxi Injection
- Breast cancer
- Non-small cell lung cancer
- Prostate cancer
- Cancer of head and neck
Benefits of Adoxi Injection
In Breast cancer
Adoxi 120mg Injection Combipack helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Adoxi 120mg Injection Combipack kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Adoxi 120mg Injection Combipack helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Adoxi 120mg Injection Combipack decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
In Cancer of head and neck
Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Adoxi 120mg Injection Combipack kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but it has some bothersome side effects. Therefore, you should discuss the risks and benefits with your doctor.
Side effects of Adoxi Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Adoxi
- Breathlessness
- Constipation
- Edema (swelling)
- Infection
- Loss of appetite
- Muscle pain
- Nail disorder
- Pain
- Weakness
How to use Adoxi Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Adoxi Injection works
Adoxi 120mg Injection Combipack is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Adoxi 120mg Injection Combipack.
Pregnancy
CONSULT YOUR DOCTOR
Adoxi 120mg Injection Combipack is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Adoxi 120mg Injection Combipack is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Adoxi 120mg Injection Combipack alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Adoxi 120mg Injection Combipack is safe to use in patients with kidney disease. No dose adjustment of Adoxi 120mg Injection Combipack is recommended.
Liver
CAUTION
Adoxi 120mg Injection Combipack should be used with caution in patients with liver disease. Dose adjustment of Adoxi 120mg Injection Combipack may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Adoxi 120mg Injection Combipack
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Quick tips
- Adoxi 120mg Injection Combipack is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.
- Do not take Adoxi 120mg Injection Combipack if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
- It may cause side effects such as swelling of hands, lips, and weight gain. To reduce these side effects your doctor may suggest some medication along with this medicine called Corticosteroids.
- Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
Fact Box
Chemical Class
Taxanes Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimicrotubule agents- Taxanes
Patient concerns
FAQs
Q. Does Adoxi 120mg Injection Combipack cause weight gain?
Yes, Adoxi 120mg Injection Combipack may cause weight gain. It may occur due to fluid retention which may initially make your feet swell and then gradually it will spread to the whole body. Call your doctor immediately if you notice swelling of feet.
Q. How long do I have to take Adoxi 120mg Injection Combipack?
You should continue to take Adoxi 120mg Injection Combipack as long as your doctor advises you. The duration of treatment varies with the type of cancer you have and other factors like your response to treatment. You should usually receive your infusion once every 3 weeks.
Q. Can I drink alcohol while on Adoxi 120mg Injection Combipack?
Adoxi 120mg Injection Combipack injection contains alcohol because of which you may experience confusion, stumbling, becoming very sleepy, or feeling like you are drunk. This may impair your ability to drive or use machinery right after receiving it. Hence, you should avoid alcohol during Adoxi 120mg Injection Combipack therapy, as it may affect you adversely.
Q. What is Adoxi 120mg Injection Combipack used for?
Adoxi 120mg Injection Combipack is commonly used for breast cancer, certain types of lung cancer, prostate, stomach, and head and neck cancers. It works by restricting cells from growing and multiplying.
Q. Is Adoxi 120mg Injection Combipack available in pill form?
No, Adoxi 120mg Injection Combipack injection comes as a liquid to be given intravenously (into a vein) by a doctor or nurse in a hospital or clinic. It is usually given over 1 hour once every 3 weeks.
Q. What blood tests are required before administration of Adoxi 120mg Injection Combipack?
Your doctor will ask you to get blood tests every time you have a scheduled dose of Adoxi 120mg Injection Combipack. You may be asked to have blood tests, such as hemogram and liver function tests, to ensure that you have enough blood cells and that your liver is functioning well enough to receive Adoxi 120mg Injection Combipack. In case of white blood cells disturbances, you may experience associated fever or infections.
Q. Is hair loss caused by Adoxi 120mg Injection Combipack irreversible?
Hair loss is a common side effect of Adoxi 120mg Injection Combipack. Normal hair growth may resume after stopping Adoxi 120mg Injection Combipack. However, in some cases there is permanent hair loss. Consult your doctor if you have any concerns regarding hair loss.
Q. Why is dexamethasone used with Adoxi 120mg Injection Combipack?
Adoxi 120mg Injection Combipack may cause fluid retention (swelling in the hands, feet, ankles and legs) as well as severe hypersensitivity reactions. To control such possibilities from occurring all patients are given corticosteroids (dexamethasone) for 3 days starting 1 day prior to Adoxi 120mg Injection Combipack administration. In case of prostate cancer (metastatic castration-resistant), the recommended regimen is oral dexamethasone given at 12 hours, 3 hours, and 1 hour before the Adoxi 120mg Injection Combipack infusion.
Q. What type of drug is Adoxi 120mg Injection Combipack?
Adoxi 120mg Injection Combipack belongs to the group of anti-cancer medicines called taxoids. It works by stopping the growth and spread of cancer cells.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 422-23.
- Docetaxel Injection. Unterach, Austria: EBEWE Pharma Ges.m.b.H. Nfg.KG; 1996 [revised Mar. 2012. [Accessed 26 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Docetaxel. [Updated 2019 Jun 30]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Adley Formulations
Address: Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India
Country of origin: India
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