Adrihal 50 Injection
Prescription Required
Product introduction
Adrihal 50 Injection is used in the treatment of various types of cancers of blood, breast, lung, ovaries and soft tissues. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
It is given as a drip or infusion vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.
The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life-threatening. Regular blood tests are required to monitor your blood cells along with the kidney, liver, and heart function during treatment with this medicine.
Before taking this medicine, tell your doctor if you have severe liver or heart-related problems, or if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.
It is given as a drip or infusion vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.
The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life-threatening. Regular blood tests are required to monitor your blood cells along with the kidney, liver, and heart function during treatment with this medicine.
Before taking this medicine, tell your doctor if you have severe liver or heart-related problems, or if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.
Uses of Adrihal Injection
Benefits of Adrihal Injection
In Cancer
Adrihal 50 Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Adrihal 50 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Adrihal Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Adrihal
- Vomiting
- Allergic reaction
- Nausea
- Mouth sore
- Hair loss
- Stomach pain
- Eye disorder
- Increased thirst
- Arrhythmia (irregular heartbeats)
- Nail disorder
How to use Adrihal Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Adrihal Injection works
Adrihal 50 Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Adrihal 50 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Adrihal 50 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Adrihal 50 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Adrihal 50 Injection may cause side effects which could affect your ability to drive.
As there is a frequent occurrence of nausea and vomiting with Adrihal 50 Injection so driving should be discouraged.
As there is a frequent occurrence of nausea and vomiting with Adrihal 50 Injection so driving should be discouraged.
Kidney
SAFE IF PRESCRIBED
Adrihal 50 Injection is safe to use in patients with kidney disease. No dose adjustment of Adrihal 50 Injection is recommended.
However, inform your doctor if you have any kidney disease.
However, inform your doctor if you have any kidney disease.
Liver
CAUTION
Adrihal 50 Injection should be used with caution in patients with liver disease. Dose adjustment of Adrihal 50 Injection may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Adrihal 50 Injection
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Quick tips
- Adrihal 50 Injection is given as an injection into the vein under the supervision of a doctor.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
- Inform your doctor if you experience fever, chills, shortness of breath and swelling of face or lips.
Fact Box
Chemical Class
Anthracycline Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkaloids-cytotoxic agents
Patient concerns
FAQs
Q. How does doxorubicin work?
Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medications called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cells. This helps treat the cancer.
Q. Is doxorubicin a vesicant?
Yes doxorubicin is a vesicant (irritant).
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.
- Doxorubicin hydrochloride. Sandwich, Kent: Pfizer Limited; 2009 [revised Feb. 2016]. [Accessed 25 Jan. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Halsted Pharma Private Limited
Address: Ground floor, Plot No.25-HIG, Survey No.912P. 913P, 941P, 944P 945 to 962 and 964P Phase XV, KPHB Colony, Kukatpally. Medchal- Malkajgiri District, Telangana State, India.
Country of origin: India
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₹1141
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1.0 Injection in 1 vial
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