Adzine 200 Injection
Prescription Required
Product introduction
Adzine 200 Injection is used in the treatment of cancers of lymphatic system and malignant melanoma (a type of skin cancer). It may be also used to treat other conditions, as determined by the doctor.
Adzine 200 Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, and decreased white blood cell count, and injection site pain,. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Adzine 200 Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, and decreased white blood cell count, and injection site pain,. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Adzine Injection
Benefits of Adzine Injection
In Malignant melanoma
Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Adzine 200 Injection sticks to the genetic code, called DNA,of the cancer cells and kills them . It also prevents their growth and further spread. This helps to treat the cancer.
In Hodgkin’s disease
Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Adzine 200 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully.
Side effects of Adzine Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Adzine
- Nausea
- Vomiting
- Injection site pain
- Decreased white blood cell count
- Loss of appetite
How to use Adzine Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Adzine Injection works
Adzine 200 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Adzine 200 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Adzine 200 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Adzine 200 Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Adzine 200 Injection may cause side effects which could affect your ability to drive.
Adzine 200 Injection may influence the ability to drive because of its central nervous system side effects.
Adzine 200 Injection may influence the ability to drive because of its central nervous system side effects.
Kidney
CAUTION
Adzine 200 Injection should be used with caution in patients with kidney disease. Dose adjustment of Adzine 200 Injection may be needed. Please consult your doctor.
Liver
CAUTION
Adzine 200 Injection should be used with caution in patients with liver disease. Dose adjustment of Adzine 200 Injection may be needed. Please consult your doctor.
What if you forget to take Adzine Injection?
If you miss a dose of Adzine 200 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Adzine 200 Injection is given as an injection into veins under the supervision of a doctor.
Fact Box
Chemical Class
Triazene Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent
Interaction with drugs
Taking Adzine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Dacarbazine from 1 day before until 1 day after taking Molgramostim. P
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Dacarbazine from 14 days before until 24 days after taking Pegfilgrast
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Dacarbazine from 1 day before until 1 day after taking Sargramostim. P
Concomitant use may increase the risk of opportunistic infections.
Do not consume Natalizumab with Dacarbazine.
Patient concerns
FAQs
How is Adzine 200 Injection administered?
Adzine 200 Injection is administered as infusion or injection. Absorption by mouth is slow and varies, therefore, intravenous (given through vein) infusion or injection administration is preferred.
Is Adzine 200 Injection a vesicant?
Adzine 200 Injection is a potent vesicant (it is corrosive), and it should be carefully administered to avoid the risk of extravasation (leaking into the tissues).
What is Adzine 200 Injection used for?
Adzine 200 Injection is used to treat skin cancer that has spread to other parts of the body (malignant melanoma), cancer of the white blood cell (Hodgkin's lymphoma) and advanced adult soft tissue sarcomas (cancer of soft tissues such as muscles, tendons, fat, and blood vessels).
How effective is Adzine 200 Injection?
Adzine 200 Injection is effective if taken at recommended dosage and duration as advised by your doctor.
Does Adzine 200 Injection cause hair loss?
Yes, hair loss is a common side effect of Adzine 200 Injection.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1686-87.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 942.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
- Dacarbazine citrate. Wedel, Germany: medac GmbH; 1997 [revised Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
- Drugs.com. Dacarbazine Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dacarbazine. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Marketer details
Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.
Country of origin: India
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₹419
Inclusive of all taxes
MRP₹427 2% OFF
1.0 Injection in 1 vial
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