Afitra 400mg Tablet
Prescription Required
Product introduction
Afitra 400mg Tablet belongs to a group of medicines called antifungals. It works by stopping the growth of fungi and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane.
Afitra 400mg Tablet should be taken in the dose and duration as prescribed by your doctor. It should be swallowed whole and can be taken with food. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop the treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse.
The most common side effects of this medicine include nausea, dizziness, headache, vomiting, diarrhea, abdominal pain, constipation, and dyspepsia. You could ask your doctor about ways of preventing or reducing these effects. Get emergency medical help if you have signs of an allergic reaction like severe skin rash, tingling, difficulty breathing, swelling of your face, lips, tongue, or throat.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking this medicine if you have a history of heart failure, a weak immune system (including HIV/AIDS), kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood.
Afitra 400mg Tablet should be taken in the dose and duration as prescribed by your doctor. It should be swallowed whole and can be taken with food. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop the treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse.
The most common side effects of this medicine include nausea, dizziness, headache, vomiting, diarrhea, abdominal pain, constipation, and dyspepsia. You could ask your doctor about ways of preventing or reducing these effects. Get emergency medical help if you have signs of an allergic reaction like severe skin rash, tingling, difficulty breathing, swelling of your face, lips, tongue, or throat.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking this medicine if you have a history of heart failure, a weak immune system (including HIV/AIDS), kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood.
Uses of Afitra Tablet
Benefits of Afitra Tablet
In Treatment of Fungal infections
Afitra 400mg Tablet is an antifungal medicine. It is used to treat infections in different parts of the body caused by fungi. It works by killing and stopping the growth of fungi. This provides relief from various symptoms caused by the infection and speeds up the healing process. You should keep taking the medicine until you complete the dose even if you get better. This will prevent the infection from returning.
Side effects of Afitra Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Afitra
- Nausea
- Abdominal pain
- Headache
How to use Afitra Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afitra 400mg Tablet is to be taken with food.
How Afitra Tablet works
Afitra 400mg Tablet is an antifungal medication. It kills fungi by destroying the fungal cell membrane. This treats your skin infection.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Afitra 400mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Afitra 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Afitra 400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Afitra 400mg Tablet may cause side effects which could affect your ability to drive.
Afitra 400mg Tablet can sometimes cause dizziness, blurred/double vision or hearing loss. This may affect your ability to drive.
Afitra 400mg Tablet can sometimes cause dizziness, blurred/double vision or hearing loss. This may affect your ability to drive.
Kidney
CAUTION
Afitra 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Afitra 400mg Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Afitra 400mg Tablet in patients with liver disease. Please consult your doctor.
Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.
Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.
What if you forget to take Afitra Tablet?
If you miss a dose of Afitra 400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Afitra 400mg Tablet helps treat fungal infections of mouth, skin, vagina or any other parts of the body.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- Take it with food, preferably at the same time everyday.
- Use a reliable method of contraception to prevent pregnancy while taking this medicine.
- Do not take indigestion remedies (antacids) within 2 hours of taking Afitra 400mg Tablet.
- Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
- Inform your doctor if you develop allergic reactions, nerve pain, or hearing loss.
Fact Box
Chemical Class
Azoles {Triazoles}
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Fungal ergosterol synthesis inhibitor
Patient concerns
User feedback
Patients taking Afitra 400mg Tablet
Once A Day
84%
Twice A Day
11%
Once A Week
5%
What are you using Afitra Tablet for?
Fungal infect*
75%
Severe fungal*
25%
*Fungal infections, Severe fungal infections
How much was the improvement?
Average
44%
Excellent
33%
Poor
22%
What were the side-effects while using Afitra 400mg Tablet?
No Side Effec*
50%
Nausea
50%
*No Side Effect
How do you take Afitra Tablet?
With food
100%
Please rate Afitra 400mg Tablet on price
Average
67%
Expensive
33%
FAQs
What is Afitra 400mg Tablet used for?
Afitra 400mg Tablet is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of the feet, or infection in the groin and buttocks. This medicine also treats persistent infection of fingernails and toenails, persistent candida (yeast) infections of vagina or candida (yeast) infections of the mouth or throat in patients with lower disease resistance. It is also used in the treatment of cryptococcal infection and infections caused by Histoplasma, aspergillus, and Blastomyces.
For how long do I need to take Afitra 400mg Tablet?
The dose and length of treatment depends on the type and site of infection and your response to the treatment. For example, if you are taking Afitra 400mg Tablet for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days, on the other hand, if you are taking it for candidal infection of the vagina, the dose may span from 1 day to 3 days depending on the dosage advised by the doctor.
I am taking Afitra 400mg Tablet for nail infection but there does not seem to be any improvement. Can I stop taking it?
No, you should not stop taking Afitra 400mg Tablet without completing the entire course because doing so may not completely cure the fungal infection. It usually takes about 6-9 months for nail lesions to disappear because after the medicine eliminates the fungus, the new nail takes several months to grow. Do not worry if you do not see any improvement during the treatment.
Why has my doctor asked me to get blood tests done?
Your doctor is probably trying to monitor your liver’s functioning. Afitra 400mg Tablet may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine, or abdominal pain while taking Afitra 400mg Tablet, you should tell your doctor immediately.
Can I take antacid and Afitra 400mg Tablet together?
Afitra 400mg Tablet can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn, or indigestion neutralize the acid produced by the stomach. Therefore, take antacids or any such medicine about 2 hours after taking Afitra 400mg Tablet. If you are taking antacids (medicines that stop the production of stomach acid), take Afitra 400mg Tablet capsules with a drink of cola.
What is drug resistance? Is it possible to develop resistance to Afitra 400mg Tablet?
Sometimes it happens that the fungi get modified in your body and the medicine no longer works. This is called drug resistance. Resistance to Afitra 400mg Tablet has been reported with some candida species (krusei, glabrata, and tropicalis). Afitra 400mg Tablet should not be used for infection caused due to these species. Take the complete course of Afitra 400mg Tablet to avoid drug resistance.
I have been on alprazolam for quite some time. Is it okay if I start Afitra 400mg Tablet now?
Yes, you can take both Alprazolam and Afitra 400mg Tablet together, but keep a watch on the side effects of alprazolam such as lightheadedness or drowsiness. If side effects appear after taking Afitra 400mg Tablet, talk to your doctor who will modify the dose of alprazolam.
My doctor prescribed Afitra 400mg Tablet to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?
Your doctor did not prescribe Afitra 400mg Tablet to your friend because Afitra 400mg Tablet interferes with the working of dofetilide. This interference can cause disturbed electrical activity of the heart, which can be harmful to the patient.
What is Afitra 400mg Tablet used for?
Afitra 400mg Tablet is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of feet, or infection in groin and buttocks. This medicine also treats persistent infection of fingernails and toenails, persistent candida (yeast) infections of vagina or candida (yeast) infections of the mouth or throat in patients with lower resistance to disease. It is also used in the treatment of cryptococcal infection and infections caused by histoplasma, aspergillus and blastomyces.
For how long do I need to take Afitra 400mg Tablet?
The dose and length of treatment will depend on the type and site of infection and your response to the treatment. For example, if you are taking Afitra 400mg Tablet for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days. While, on the other hand, if you are taking it for candidal infection of vagina, the dose may take about 1 to 3 3 days depending on the dosage advised by the doctor.
What should I do if I skip a dose of Afitra 400mg Tablet?
If you forget to take your dose, take the missed dose as soon as you remember. However, if it is time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the forgotten dose.
I am taking Afitra 400mg Tablet for nail infection but there does not seem to be any improvement. Can I stop taking it?
No, you should not stop taking Afitra 400mg Tablet without completing the entire course. This is because if you stop the medication then your fungal infection may not get completely cured. It usually takes about 6-9 months for the nail lesions to get cured and after that the new nail also takes several months to grow. Therefore, do not worry if you do not see any improvement during the treatment.
Why has my doctor asked me to get blood tests done?
Your doctor may have prescribed blood tests to monitor your liver’s functioning. This is because the use of Afitra 400mg Tablet may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine or abdominal pain while taking Afitra 400mg Tablet, immediately inform your doctor.
Can I take an antacid and Afitra 400mg Tablet together?
Afitra 400mg Tablet can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn or indigestion neutralize the acid produced by the stomach. Therefore, it is advised to avoid taking antacids or any such medicine for a minimum of 2 hours after taking Afitra 400mg Tablet. However, if you are taking antacids (medicines that stop the production of stomach acid), take Afitra 400mg Tablet capsules with a drink of cola.
What is drug resistance? Is it possible to develop resistance to Afitra 400mg Tablet?
Drug resistance is a condition when the fungi get modified in your body and the medicine is not able to work. There are reports which suggest resistance of some candida species (krusei, glabrata and tropicalis) with Afitra 400mg Tablet. Afitra 400mg Tablet should not be used for infection caused due to these species. It is advised to take the complete course of Afitra 400mg Tablet to avoid drug resistance.
I am on alprazolam for quite some time. Is it okay if I start Afitra 400mg Tablet now?
Yes, you can take both Alprazolam and Afitra 400mg Tablet together, but keep a watch on the side effects of Alprazolam such as lightheadedness or drowsiness. If you experience side effects after taking Afitra 400mg Tablet, talk to your doctor who will modify the dose of alprazolam.
My doctor prescribed Afitra 400mg Tablet to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?
Your doctor did not prescribe Afitra 400mg Tablet to your friend because Afitra 400mg Tablet interferes with the working of dofetilide. This interference can cause disturbed electrical activity of the heart, which can be harmful for the patient.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1576-79.
- Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 839-40.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 749-51.
- Itraconazole. Turnhout, Belgium: Sanico N.V.; 1992 [revised Apr. 2010]. [Accessed 29 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
- New Zealand Data Sheet. Itrazole. Aukland, new Zealand: Viatris Ltd.; 2022. [Accessed 07 Jul. 2023]. (online) Available from:
- Kurn H, Wadhwa R. Itraconazole. [Updated 2023 Apr 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 07 Jul. 2023]. (online) Available from:
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