Amikacin Sulphate 500mg Injection
Prescription Required
Product introduction
Amikacin Sulphate 500mg Injection is an antibiotic used to prevent or treat various bacterial infections. These may include infections of the urinary tract, bones, joints, lungs (e.g., pneumonia), brain, blood, etc. It is also used in hospitalized patients to prevent infections.
Amikacin Sulphate 500mg Injection works by stopping the growth of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a doctor and should not be self-administered. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
Common side effects of this medicine include injection site reactions, kidney problems, and hearing problems. Consult your doctor if any of these side effects persist or if your condition does not improve despite treatment.
Some patients receiving high doses may develop balance disorder (loss of balance), kidney damage, and hearing loss. Therefore, please follow all the instructions given by your doctor while using this medicine. Your doctor may also monitor you with regular kidney function tests, hearing tests, and urine tests during treatment. This medication is not recommended for use during pregnancy. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Uses of Amikacin Sulphate Injection
Benefits of Amikacin Sulphate Injection
In Treatment of Bacterial infections
Amikacin Sulphate 500mg Injection is the injection form of an antibiotic medicine that stops the growth of the infection-causing bacteria in your body. It is often injected by a doctor or a nurse, either into a vein or a muscle. This medicine treats many types of infections, such as urinary tract infections, bones and joints, lungs (e.g., pneumonia), brain, and blood. This medicine usually makes you feel better within a few days. Follow your doctor's instructions carefully to get maximum benefit.
Side effects of Amikacin Sulphate Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amikacin Sulphate
- Injection site reactions (pain, swelling, redness)
- Hearing impairment
- Change in blood test results
- Renal impairment
How to use Amikacin Sulphate Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Amikacin Sulphate Injection works
Amikacin Sulphate 500mg Injection is an antibiotic. It stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. It works by binding to a part of the bacteria responsible for protein production (30S ribosomal subunit), stopping their growth. This leads to the production of faulty proteins or a complete halt in protein synthesis, ultimately killing the bacteria or stopping their growth.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amikacin Sulphate 500mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Amikacin Sulphate 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Amikacin Sulphate 500mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amikacin Sulphate 500mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Amikacin Sulphate 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Amikacin Sulphate 500mg Injection may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Amikacin Sulphate 500mg Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Amikacin Sulphate Injection?
If you missed a dose of Amikacin Sulphate 500mg Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Amikacin Sulphate 500mg Injection is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle.
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
- Your doctor may get regular blood, urine, or hearing tests while you are on this medication.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
- Discontinue Amikacin Sulphate 500mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of your face and mouth, or difficulty breathing.
Fact Box
Chemical Class
Aminoglycosides
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Bacterial Protein Synthesis Inhibitors- Aminoglycosides
Interaction with drugs
Taking Amikacin Sulphate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Your doctor may monitor your electrolyte levels, kidney function, and hearing ability along with your overall treatment.
Concurrent use may increase the risk of kidney impairment,
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Co
Do not consume Tenofovir disoproxil fumarate with Amikacin. If concurrent use is essential, your doctor may monitor your kidney function closely.
Concurrent use may increase the r
If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Concurrent use may potentially damage the kidneys.
Do not consume Colistin Sulphate with Amikacin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use
Patient concerns
User feedback
Patients taking Amikacin Sulphate 500mg Injection
Twice A Day
51%
Once A Day
36%
Alternate Day
4%
Twice A Month
3%
Once A Month
2%
Twice A Week
2%
Once A Week
1%
Thrice A Day
1%
What are you using Amikacin Sulphate Injection for?
Bacterial inf*
66%
Others
16%
Severe bacter*
9%
Tuberculosis *
9%
*Bacterial infections, Severe bacterial infections, Tuberculosis (TB)
How much was the improvement?
Average
41%
Excellent
33%
Poor
26%
What were the side-effects while using Amikacin Sulphate 500mg Injection?
Hearing loss
23%
Nausea
23%
Diarrhea
15%
Balance disor*
8%
Application s*
8%
*Balance disorder (loss of balance), Application site irritation
How do you take Amikacin Sulphate Injection?
With food
62%
Empty stomach
25%
With or witho*
12%
*With or without food
Please rate Amikacin Sulphate 500mg Injection on price
Average
46%
Expensive
38%
Not Expensive
17%
FAQs
For how long can Amikacin Sulphate 500mg Injection be taken?
Your doctor will decide your dose depending on the condition you are being treated for. Continue taking Amikacin Sulphate 500mg Injection in the dose and duration prescribed by the doctor to get maximum benefit. Do not alter the dose of the medicine on your own; consult your doctor first.
Is Amikacin Sulphate 500mg Injection safe?
Amikacin Sulphate 500mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
How is Amikacin Sulphate 500mg Injection administered?
Amikacin Sulphate 500mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get the maximum benefit from Amikacin Sulphate 500mg Injection.
Can I take a higher than the recommended dose of this medicine?
No, Amikacin Sulphate 500mg Injection should be taken in the recommended dose only. Overdose of Amikacin Sulphate 500mg Injection can increase the risks of side effects. If you experience an increase in the severity of your symptoms during the treatment, please consult your doctor for re-evaluation.
What are the instructions for the storage and disposal of Amikacin Sulphate 500mg Injection?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.
What if I don't get better after using Amikacin Sulphate 500mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, consult your doctor if your symptoms are getting worse while using this medicine. The doctor may modify the dose or suggest an alternative medicine.
Can I stop taking Amikacin Sulphate 500mg Injection when I feel better?
No, do not stop taking Amikacin Sulphate 500mg Injection and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.
Can I take alcohol while on Amikacin Sulphate 500mg Injection?
You should avoid alcohol while being on treatment with Amikacin Sulphate 500mg Injection. Alcohol consumption may worsen the dizziness and sleepiness that might be caused by Amikacin Sulphate 500mg Injection. However, if you do have alcohol and experience any side effects, consult your doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- MacDougall C, Chambers HF. Aminoglycosides. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1516-17.
- Chambers HF, Deck DH. Aminoglycosides & Spectinomycin. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 812.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 51.
- Amikacin [EMC Label]. Hurley Maidenhead: Hospira UK Limited; 2015. [Accessed 30 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
- Amikacin Sulfate Injection [Product Monograph]. Kirkland, Canada: VPI Pharmaceuticals Inc. 2020. [Accessed 07 Mar. 2025] (online) Available from:
- Amikacin Sulfate [Product Monograph]. Schaumburg, IL: Sagent Pharmaceuticals; 2022. [Accessed 07 Mar. 2025] (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
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