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AMIT 50 MG TABLET

Prescription Required

Product introduction

AMIT 50 MG TABLET is a tricyclic antidepressant. Different doses of this medicine help in treating and preventing different problems such as depression, neuropathic pain, and migraine.

AMIT 50 MG TABLET is normally taken before bedtime because it can make you feel sleepy. It can be taken with or without food. The dose and how often you need to take it will be decided by your doctor so that you get the right amount to control your symptoms. The initial dose should be increased with great caution under close supervision. This medicine may not work straight away and it could be several weeks before you get the full effects.

How long you need to use it will depend on what you are taking it for, but it is important to continue taking this medication even if you feel well. Do not stop taking the medicine suddenly without talking to your doctor. Stopping the medicine suddenly can worsen your conditions or cause other symptoms. Your dose may be modified or gradually decreased before stopping the medication.

The most common side effects of this medicine include nausea, constipation, sweating, dry mouth, sleepiness, tremor, dizziness, headache, speech disorder, accommodation disorder, increased heart rate, orthostatic hypotension, and nasal congestion. It may also make you aggressive or confused and can lead to weight gain in some people.

This medicine is not addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.


Benefits of Amit Tablet

In Treatment of Migraine

AMIT 50 MG TABLET helps prevent migraines by changing the way that your nerves receive pain signals. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Amit Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amit

  • Nausea
  • Constipation
  • Dryness in mouth
  • Aggressive behavior
  • Nasal congestion (stuffy nose)
  • Sleepiness
  • Dizziness
  • Headache
  • Decreased libido
  • Fatigue
  • Confusion
  • Tremors
  • Speech disorder
  • Weight gain
  • Taste change
  • Paresthesia (tingling or pricking sensation)
  • Abnormality of voluntary movements
  • Loss of accommodation
  • Micturition disorders
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Erectile dysfunction
  • Abnormal ECG
  • Decreased sodium level in blood

How to use Amit Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. AMIT 50 MG TABLET may be taken with or without food, but it is better to take it at a fixed time.

How Amit Tablet works

AMIT 50 MG TABLET contains Amitriptyline, a tricyclic antidepressant. It has anticholinergic and sedative properties. It prevents the reuptake, and hence the inactivation of neurotransmitters called noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with AMIT 50 MG TABLET.
Pregnancy
CONSULT YOUR DOCTOR
AMIT 50 MG TABLET may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
AMIT 50 MG TABLET is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
AMIT 50 MG TABLET may cause side effects which could affect your ability to drive.
AMIT 50 MG TABLET may impair your alertness which may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
AMIT 50 MG TABLET is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of AMIT 50 MG TABLET may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
AMIT 50 MG TABLET should be used with caution in patients with liver disease. Dose adjustment of AMIT 50 MG TABLET may be needed. Please consult your doctor.
Use of AMIT 50 MG TABLET is not recommended in patients with severe liver disease.

What if you forget to take Amit Tablet?

If you miss a dose of AMIT 50 MG TABLET, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
AMIT 50 MG TABLET
₹2.97/Tablet
Tryptomer 50mg Tablet
Dr Reddy's Laboratories Ltd
₹6.67/tablet
125% costlier
Eliwel 50mg Tablet
Sun Pharmaceutical Industries Ltd
₹2.75/tablet
7% cheaper
Amitril DS Tablet
Sigmund Promedica
₹3.11/tablet
5% costlier
Cotrip 50mg Tablet
Consern Pharma Limited
₹4.38/tablet
47% costlier
Tryp 50mg Tablet
Theo Pharma Pvt Ltd
₹2.58/tablet
13% cheaper

Quick tips

  • It may take 4 to 6 weeks for AMIT 50 MG TABLET to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking AMIT 50 MG TABLET as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.

Fact Box

Chemical Class
Dibenzocycloheptenes Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)

Interaction with drugs

Taking Amit with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a fatal increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of co... More
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Concomitant use may affect heart rhythm. Do not consume Domperidone with Amitriptyline.
Concurrent use may cause serotonin syndrome. Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory imp... More
Concurrent use may cause serious disturbance in heart rhythm. If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, w... More

Patient concerns

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I have Obsessive compulsive Disorder. Prescribe the medication.
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly share your symptoms of your Problem
Sir i am suffering from Anxiety, IBS and Obsessive compulsive disorder I want to how i get Ayurveda medicine
Dr. Aanchal Maheshwari
Ayurveda
You should contact Ayurvedic doctor in person before starting the treatment
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FAQs

What other lifestyle changes should I make to get maximum benefit of AMIT 50 MG TABLET?

Antidepressants, including AMIT 50 MG TABLET, are just one of several approaches to treat depression. Certain lifestyle changes can help you get maximum benefit of AMIT 50 MG TABLET and help you recover fast. Keeping active and eating a healthy diet can make a significant difference to how quickly you recover from depression. Think positively and try to discuss your thoughts with others to reduce stress. Practice yoga or take up a hobby. Ensure that you have a sound sleep to calm your mind. Stay away from smoking or alcohol consumption as these will only worsen your depression. Take your medicines as prescribed even if you start feeling better.

Is there anything I need to be careful about while on therapy with AMIT 50 MG TABLET?

AMIT 50 MG TABLET may cause drowsiness and dizziness, especially in the beginning of the treatment. So, avoid driving or using machinery until you know how the medicine affects you. Also, it is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Can the use of AMIT 50 MG TABLET affect my sex life?

Yes, AMIT 50 MG TABLET can affect sex life in both men and women. It may cause decreased sexual desire or you may experience discomfort during intercourse. Men may experience inability to develop or maintain an erection during sexual activity and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine but consult your doctor.

I have been taking AMIT 50 MG TABLET for depression since a week and recently I have been wanting to harm myself. What should I do? Is it because of the medicine?

You should immediately consult your doctor or go to the hospital. Your suicidal tendencies may have increased because of your disease or the medicine. Generally, AMIT 50 MG TABLET takes about 2 weeks to show its effect but may take longer. Therefore, when you start taking AMIT 50 MG TABLET, you may have thoughts about killing or harming yourself. This is more common in people who previously had suicidal tendencies or are young adults (less than 25 years old). However, the effect of medicine is different for every individual.

Can AMIT 50 MG TABLET cause urinary problems?

Yes, AMIT 50 MG TABLET can cause urinary problems. It is more commonly seen in elderly patients who are more than 65 years old. The patient may face difficulty in passing urine which can further lead to a urinary tract infection. Consult your doctor immediately if you develop these symptoms.

If my pain is not relieved, can I take more than the recommended dose?

No, you should use AMIT 50 MG TABLET strictly as prescribed by the doctor. If the dose exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth, tiredness, difficulty in walking, fever, difficulty in breathing, blue discoloration of the skin and decreased heartbeat. Your pain may not be relieved because AMIT 50 MG TABLET takes about 2 weeks to show its effect, but it may take longer in some cases. The duration of treatment can differ from individual to individual. Consult your doctor if your symptoms are not relieved.

Does AMIT 50 MG TABLET cause any effect on pregnancy or the newborn?

Do not take AMIT 50 MG TABLET during pregnancy unless recommended by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as irritability, rigidity, irregular body movements, irregular breathing, poor drinking, loud crying, difficulty in urinating and constipation.

I have been prescribed AMIT 50 MG TABLET for pain. When will I start feeling better?

You may start feeling better after 2 weeks of starting AMIT 50 MG TABLET. However, it may take 4-6 weeks to see the full benefits of the medicine.

Can I stop taking AMIT 50 MG TABLET when my pain is relieved?

No, do not stop taking AMIT 50 MG TABLET even if the pain is relieved. You should use AMIT 50 MG TABLET as advised by the doctor. Stopping the medicine suddenly may cause unpleasant symptoms like headache, feeling unwell, sleeplessness and irritability. Consult your doctor for the duration of the treatment since the dose of AMIT 50 MG TABLET needs to be reduced gradually.

How long does AMIT 50 MG TABLET take to work?

You may see an improvement in your symptoms after a couple of weeks, although it usually takes between 4 and 6 weeks before you feel the benefits. Do not stop taking AMIT 50 MG TABLET after 1 or 2 weeks just because you feel it is not helping your symptoms. Give the medicine at least 6 weeks to work.

How will AMIT 50 MG TABLET make me feel?

Antidepressants like AMIT 50 MG TABLET help to gradually lift your mood. You may notice that you sleep better and are less anxious. You may worry less about little things that used to bother you. AMIT 50 MG TABLET will not make you feel excessively or unusually happy. It will help you feel like yourself again.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Amitriptyline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 25-30.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 58-59.
  3. Amitriptyline. Princeton: Sandoz Inc; 2014. [Accessed on 19 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amitriptyline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
  6. Amitriptyline Hydrochloride [Drug Label]. Ahmedabad, Gujarat: Intas Pharmaceuticals Limited; 2016. [Accessed 25 Jul. 2024] (online) Available from: External Link

Marketer details

Name: Orchid Chemicals & Pharmaceuticals Ltd
Address: Orchid Towers', #313, Valluvar Kottam High Road, Nungambakkam, Chennai - 600 034, Tamil Nadu, India
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present

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