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MD (Pharmacology), MBBS
Last updated
19 Nov 2024 | 01:08 AM (IST)

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Amitone Plus Tablet

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Product introduction

Amitone Plus Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.

Amitone Plus Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Amitone Plus Tablet

Benefits of Amitone Plus Tablet

In Treatment of Depression

Amitone Plus Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Amitone Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amitone Plus

  • Constipation
  • Difficulty in urination
  • Weight gain
  • Confusion
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Uncoordinated body movements
  • Depression
  • Memory impairment

How to use Amitone Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitone Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amitone Plus Tablet works

Amitone Plus Tablet is a combination of two medicines:.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Amitone Plus Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Amitone Plus Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Amitone Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amitone Plus Tablet may cause side effects which could affect your ability to drive.
As Amitone Plus Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amitone Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amitone Plus Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Amitone Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Amitone Plus Tablet may be needed. Please consult your doctor.

What if you forget to take Amitone Plus Tablet?

If you miss a dose of Amitone Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Amitone Plus Tablet
₹4.36/Tablet
Amixide-H Tablet
Sun Pharmaceutical Industries Ltd
₹5.43/tablet
25% costlier
Libotryp 12.5 mg/5 mg Tablet
Dr Reddy's Laboratories Ltd
₹4.63/tablet
6% costlier
Aculip H 12.5 mg/5 mg Tablet
Shine Pharmaceuticals Ltd
₹4.29/tablet
2% cheaper
Amitryn-C Tablet
KC Laboratories
₹4.37/tablet
same price
₹3.68/tablet
16% cheaper

Quick tips

  • Amitone Plus Tablet is prescribed for the treatment of depression.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Do not stop taking Amitone Plus Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Inform your doctor if you are taking any other antidepressants.
  • Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
  • Avoid alcohol while taking Amitone Plus Tablet.
  • If you have diabetes, you will be asked to monitor your blood glucose level regularly as Amitone Plus Tablet may affect the levels of sugar in your blood.
  • Amitone Plus Tablet is prescribed for the treatment of depression.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Do not stop taking Amitone Plus Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Inform your doctor if you are taking any other antidepressants.
  • Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
  • Avoid alcohol while taking Amitone Plus Tablet.
  • If you have diabetes, you will be asked to monitor your blood glucose level regularly as Amitone Plus Tablet may affect the levels of sugar in your blood.

Fact Box

Habit Forming
Yes
Therapeutic Class
NEURO CNS

Patient concerns

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heat from head, and also pain,please tell medicine
Dr. Vikas Sharma
Neurology
amitone 10 mg hs
Heavy headache problem first started to Back side later around the head
Dr. Vikas Sharma
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Tab amitone 10 mg Hs
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User feedback


FAQs

Are there any important warnings associated with use of Amitone Plus Tablet?

During the first few months of treatment, Amitone Plus Tablet may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

Can I stop taking Amitone Plus Tablet when my symptoms are relieved?

No, you should continue to take Amitone Plus Tablet, even if you feel well. If you stop Amitone Plus Tablet suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

How to manage weight gain associated with the use of Amitone Plus Tablet?

There are reports which suggest that the use of Amitone Plus Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

What are the instructions for storage and disposal of Amitone Plus Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of Amitone Plus Tablet cause sleepiness?

Yes, Amitone Plus Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Can the use of Amitone Plus Tablet affect my sexual life?

The use of Amitone Plus Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

Can I drink alcohol while taking Amitone Plus Tablet?

No, do not drink alcohol while you are taking Amitone Plus Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Amitone Plus Tablet.

Can the use of Amitone Plus Tablet change the color of urine?

Yes, Amitone Plus Tablet can the change the color of the urine to blue or green. This change of color is expected while using Amitone Plus Tablet, and it is not harmful. Your urine color becomes normal once you stop taking Amitone Plus Tablet.

How long does Amitone Plus Tablet take to work?

Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Amitone Plus Tablet, although some people will start to feel better sooner. When taking Amitone Plus Tablet, it is important to give it time to work.

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References

  1. DailyMed. Chlordiazepoxide and amitriptyline hydrochloride. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. MedlinePlus. Chlordiazepoxide. [Accessed 10 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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