Amlokos 2.5mg Tablet belongs to a class of medicines known as calcium channel blockers. It is used to treat high blood pressure (hypertension) and prevent angina (heart-related chest pain). It lowers blood pressure and reduces the heart's workload, which helps prevent heart attacks and strokes.
Amlokos 2.5mg Tablet may be prescribed alone or along with other medicines. The dose depends on what you are taking it for and the severity of your condition. You can take it at any time of the day, with or without food, but it is best to take it at about the same time each day. You should take this medicine for as long as it is prescribed for you. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping yourself active with regular exercise, managing your weight, and eating a healthy diet will also help control your blood pressure.
The most common side effects include headache, edema, fatigue, nausea, abdominal pain, and somnolence. Consult your doctor if any of these side effects bother you or do not go away. They may be able to suggest ways to prevent or reduce the side effects. There has been reports of lichenoid keratosis (a benign, inflamed, solitary skin lesion, typically brownish or reddish, found on sun-exposed areas) in some patients taking Amlokos 2.5mg Tablet, if you experience this, let your doctor know.
Before taking it, let your doctor know if you have any liver, heart, or kidney problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. You also need to tell your doctor about all the other medicines you are taking, especially those used to treat high blood pressure or heart conditions. You should have your blood pressure checked regularly to make sure that this medicine is working properly.
In Treatment of Hypertension (high blood pressure)
Amlokos 2.5mg Tablet works by relaxing the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.
Side effects of Amlokos Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amlokos
Headache
Fatigue
Nausea
Abdominal pain
Sleepiness
Edema (swelling)
How to use Amlokos Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amlokos 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Amlokos Tablet works
Amlokos 2.5mg Tablet is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. In heart-related chest pain (angina), the enhanced blood flow in the body relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Amlokos 2.5mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Amlokos 2.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Amlokos 2.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Amlokos 2.5mg Tablet may cause side effects which could affect your ability to drive. Amlokos 2.5mg Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.
Kidney
SAFE IF PRESCRIBED
Amlokos 2.5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Amlokos 2.5mg Tablet is recommended.
Liver
CAUTION
Amlokos 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amlokos 2.5mg Tablet may be needed. Please consult your doctor. Amlokos 2.5mg Tablet is started at a lower dose in patients with liver disease and further increased slowly with careful monitoring.
What if you forget to take Amlokos Tablet?
If you miss a dose of Amlokos 2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Amlokos 2.5mg Tablet to improve your blood pressure and/or to reduce the number and severity of angina attacks.
Lowering blood pressure reduces the chance of future heart attack and stroke.
Take it at the same time every day to help you remember to take it.
A sudden drop in your blood pressure may occur, especially when you first start taking Amlokos 2.5mg Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Amlokos 2.5mg Tablet affects you.
Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.
Fact Box
Chemical Class
Dihydropyridinecarboxylic acids derivatives
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Calcium Channel Blockers- Dihydropyridines (DHP)
Interaction with drugs
Taking Amlokos with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may result in an overgrowth of gum tissue around the teeth. Amlodipine may raise blood levels of Ciclosporin.
Do not consume Ciclosporin with Amlodipine. If concurre... More
Concurrent use may result in an overgrowth of gum tissue around the teeth. Amlodipine may raise blood levels of Ciclosporin.
Do not consume Ciclosporin with Amlodipine. If concurre... More
Concurrent use may weaken the blood pressure-lowering effect of Amlodipine.
Do not use Progesterone with Amlodipine, especially if you have heart disease. If concurrent use is ess... More
Concurrent use may weaken the blood pressure-lowering effect of Amlodipine.
Do not use Estradiol with Amlodipine, especially if you have heart disease. If concurrent use is essent... More
Concurrent use may increase the risk of muscle damage.
Talk to your doctor if you notice any unusual symptoms. Your doctor may adjust the dose if required.
How long does it take for Amlokos 2.5mg Tablet to work?
Amlokos 2.5mg Tablet starts working on the day it is taken. However, it may take weeks to see the full effect. You should continue taking the medicine even if you feel better or if you do not notice any considerable difference. Consult your doctor if you have any concerns or you feel worse after taking the medicine.
Does Amlokos 2.5mg Tablet cause itching?
Amlokos 2.5mg Tablet may cause itching in some patients, though it is an uncommon side effect. However, if you experience severe itching contact your doctor.
Is Amlokos 2.5mg Tablet bad for the kidneys?
No, there is no evidence that Amlokos 2.5mg Tablet causes deterioration of kidney problems. Amlokos 2.5mg Tablet can be used in normal doses in patients with kidney problems. In fact, its blood pressure-lowering effect, it helps to prevent injury to the kidneys due to hypertension.
Should I take Amlokos 2.5mg Tablet in the morning or at night?
Amlokos 2.5mg Tablet can be taken anytime of the day. Usually, it is advised to be taken in the morning, but your doctor may advise to take it in the evening as well. You should take it at the same time each day so that you remember to take it and consistent levels of medicine are maintained in the body.
For how long do I need to take Amlokos 2.5mg Tablet?
You should keep on taking Amlokos 2.5mg Tablet for as long as your doctor has recommended you to take it. You may need to take it lifelong. Do not stop taking it, even if you feel well or your blood pressure is well controlled. If you stop taking Amlokos 2.5mg Tablet, your blood pressure may increase again and your condition may worsen.
Is Amlokos 2.5mg Tablet a beta-blocker?
No, Amlokos 2.5mg Tablet is not a beta-blocker. It belongs to a class of medicines known as calcium channel blockers. It lowers blood pressure by relaxing the blood vessels so that blood can easily flow through the blood vessels.
What are the serious side effects of Amlokos 2.5mg Tablet?
Amlokos 2.5mg Tablet may cause some serious side effects such as liver problems (yellowing of skin, nausea, vomiting, and loss of appetite), pancreatitis (severe stomach pain, nausea, and vomiting), and recurrent chest pain which may be indicative of a heart attack. However, these side effects are rarely seen. Remember that your doctor has prescribed this medicine to you because the benefit to you is greater than the risk of any potential side effects. Follow your doctor's advice.
What should I avoid while taking Amlokos 2.5mg Tablet?
Consult your doctor first before starting any new prescription or non-prescription medicines or supplements. Take low sodium and low-fat diet, and adhere to the lifestyle changes as advised by your doctor. Avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking Amlokos 2.5mg Tablet. Stop smoking and taking alcohol as this helps to lower your blood pressure and prevents heart problems.
I have developed ankle edema and swelling over my feet after using a Amlokos 2.5mg Tablet. What should I do?
Amlokos 2.5mg Tablet can cause ankle or foot swelling. To reduce swelling raise your legs while you are sitting down. Talk to your doctor if it does not go away.
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References
Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 758-60.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 60-61.
Opie LH. Calcium Channel Blockers. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 86-88.
Amlodipine besylate [FDA Label]. New York, NY: Pfizer; 2011. [Accessed 23 Jan. 2019] (online) Available from:
Amlodipine besylate [FDA Label]. New York, NY: Pfizer Labs.; 1987 [revised May 2011]. [Accessed 14 Mar. 2019] (online) Available from:
Drugs.com. Amlodipine Pregnancy and Breastfeeding Warnings. [Accessed 14 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amlodipine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Amlodipine. [Accessed 14 Mar. 2019] (online) Available from:
Marketer details
Name: Raptakos Brett & Co Ltd
Address: 253, Dr Annie Besant Road, Worli, Mumbai – 400 030, India.
Country of origin: India
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