Amlosafe-LS 5/5 Tablet is used to treat hypertension (high blood pressure). This is a combination of two medicines that controls blood pressure when a single medication is not effective. It helps to lower high blood pressure and thus reduces the chances of future heart attack and stroke.
You can take Amlosafe-LS 5/5 Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor’s advice while taking this medicine.
It may cause side effects like ankle swelling, headache, cough, weakness, and tiredness. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This might raise the level of potassium in the blood, hence avoid potassium rich food or supplements. You may be asked for regular monitoring of blood pressure, kidney function, and electrolytes level while on the treatment.
Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.
In Treatment of Hypertension (high blood pressure)
Hypertension (high blood pressure) increases the risk of heart attack, stroke, and kidney problems over time. Amlosafe-LS 5/5 Tablet is used to manage high blood pressure; this medicine relaxes blood vessels and reduces the workload on the heart. It helps maintain healthy blood pressure levels and supports long-term heart and vascular health.
Side effects of Amlosafe-LS Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amlosafe-LS
Decreased blood pressure
Upset stomach
Headache
Tiredness
Palpitations
Increased potassium level in blood
Sleepiness
Cough
Taste change
Flushing (sense of warmth in the face, ears, neck and trunk)
Ankle swelling
How to use Amlosafe-LS Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amlosafe-LS 5/5 Tablet may be taken with or without food.
How Amlosafe-LS Tablet works
Amlodipine and lisinopril which lower blood pressure effectively. It works by relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amlosafe-LS 5/5 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Amlosafe-LS 5/5 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
CONSULT YOUR DOCTOR
Amlosafe-LS 5/5 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Amlosafe-LS 5/5 Tablet may cause side effects that could affect your ability to drive. Amlosafe-LS 5/5 Tablet may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.
Kidney
CAUTION
Amlosafe-LS 5/5 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
CAUTION
Amlosafe-LS 5/5 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.
What if you forget to take Amlosafe-LS Tablet?
If you miss a dose of Amlosafe-LS 5/5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Sir, My right side head is tingling rarely. I am taking Amlosafe AT at morning, and Envas 10 at evening. Now blood pressure is normal level. Please help sir
What were the side-effects while using Amlosafe-LS 5/5 Tablet?
Headache
20%
Ankle swellin*
20%
Sleepiness
20%
Increased pot*
20%
No Side Effec*
20%
*Ankle swelling, Increased potassium level in blood, No Side Effect
How do you take Amlosafe-LS Tablet?
With or witho*
50%
With food
50%
*With or without food
Please rate Amlosafe-LS 5/5 Tablet on price
Average
67%
Expensive
33%
FAQs
What is Amlosafe-LS 5/5 Tablet used for?
Amlosafe-LS 5/5 Tablet is used to treat high blood pressure (hypertension). This medicine helps lower blood pressure, improve blood flow, and reduce strain on the heart, thereby reducing the risk of future heart attack and stroke.
Who should not take Amlosafe-LS 5/5 Tablet?
Individuals should not take Amlosafe-LS 5/5 Tablet if they are allergic to any ingredient present in it, have a history of angioedema (swelling under the skin), are pregnant, or have certain rare hereditary sugar metabolism problems.
What precautions should I take while using Amlosafe-LS 5/5 Tablet?
While using Amlosafe-LS 5/5 Tablet, tell your doctor if you have kidney or liver problems, heart failure, low blood pressure, or are on water tablets (diuretics). Avoid salt substitutes containing potassium unless approved by your doctor. Your blood pressure, kidney function, and potassium levels should be monitored regularly.
Can Amlosafe-LS 5/5 Tabletl affect my ability to drive?
Yes, Amlosafe-LS 5/5 Tablet may cause dizziness, tiredness, or nausea in some people, especially when starting treatment. If you feel unwell, avoid driving or operating heavy machinery.<br>
How long does it take for Amlosafe-LS 5/5 Tablet to work?
The exact time Amlosafe-LS 5/5 Tablet takes to work is not known. However, your blood pressure usually starts to improve within a few hours of taking the first dose. The full effect may take a few weeks. Continue taking it regularly even if you feel well.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
ScienceDirect. Amlodipine. [Accessed 11 Apr. 2019] (online) Available from:
Amlodipine besylate. New York, New York: Pfizer Inc.; 1987 [revised May 2011]. [Accessed 11 Apr. 2019] (online) Available from:
Amlodipine and Lisinopril. Dehradun, Uttarakhand: Cris Pharma (India) Ltd.; 2022. [Accessed 28 Oct. 2025] (online). Available from:
Marketer details
Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India. / Regd, Office: 23 -A Shah Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai-400053 Maharashtra, India
Country of origin: India Expires on or after: April, 2027
A licensed vendor partner from your nearest location will deliver Amlosafe-LS 5/5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID:[email protected] Phone Number: 0124-4166666 Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India