Aprezo 30mg Tablet is used in the treatment of moderate to severe plaque psoriasis which is a type of skin condition. This medicine is used when other conventional treatments cannot be used or if the patient is not responsive or intolerant to any of these treatments.
Aprezo 30mg Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. You may need to monitor your weight regularly while taking the medicine as it may cause weight loss.
Using this medicine may cause few common side effects such as nausea, diarrhea, vomiting, headache, and upper respiratory tract infection. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.
Uses of Aprezo Tablet
Plaque psoriasis
Benefits of Aprezo Tablet
In Plaque psoriasis
Plaque psoriasis is the most common form of psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Aprezo 30mg Tablet reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Aprezo Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aprezo
Diarrhea
Nausea
Vomiting
Headache
Upper respiratory tract infection
How to use Aprezo Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aprezo 30mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Aprezo Tablet works
Aprezo 30mg Tablet is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of these conditions.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Aprezo 30mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Aprezo 30mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Aprezo 30mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Aprezo 30mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Aprezo 30mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Aprezo 30mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Aprezo 30mg Tablet is safe to use in patients with liver disease. No dose adjustment of Aprezo 30mg Tablet is recommended.
What if you forget to take Aprezo Tablet?
If you miss a dose of Aprezo 30mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Aprezo 30mg Tablet is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
Monitor your weight regularly as Aprezo 30mg Tablet may cause weight loss.
Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
Fact Box
Chemical Class
Isoindole Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Phosphodiesterase-IV inhibitors (PsA & PSO)
Patient concerns
I have plaque psoriasis. and suddenly I got pustular psoriasis in other areas where skin was normal. now it pains a lot at the affected area
Dr. Souvik Sardar
Dermatology
See these are diseases wch can't be treated by online consultation U need to visit a dermatologist for a face to face consultation and examination Many things are to be considered before prescribing medicines in these cases
Hving plaque and scalp psorasis for the last 4-5 years. Itching very heavily, sometime bleeding, plaque spot on legs and back
Dr. Atula Gupta
Dermatology
kindly send picture of affected area for better diagnosis & treatment.Use SILKIN Scalp Solution / Cosalic -K Solution for application 3 times in a week. Topsor / Saclo lotion for application thrice a week. Cap. Maxepa once daily for 3 months. Avoid smoking and stress.
When I move my tongue both sides I have a feeling that something is there at both sides. I feel its a like a pimple. It's very irritating Please help me in this case
Dr. Vijay Verma
ENT
I think it is dental plaque which was hurting get dental opinion
No, Aprezo 30mg Tablet is not an immunosuppressant. It belongs to a class of medicines known as phosphodiesterase 4 inhibitors (PDE4) which work by blocking the activity of PDE4. PDE4 is found in inflammatory cells and blocking it helps in reducing the molecules responsible for inflammation.
How long does it take for Aprezo 30mg Tablet to work?
Aprezo 30mg Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term treatment and may take about 16 weeks to show an improvement.
Can Aprezo 30mg Tablet cause depression?
Yes, Aprezo 30mg Tablet may cause depression as a side effect. The patient may also develop suicidal thoughts. It should be avoided in patients with a history of depression. In case you develop any of these symptoms, consult your doctor immediately or ask your friends or relatives to help seek medical advice.
Does Aprezo 30mg Tablet cause weight reduction?
Yes, Aprezo 30mg Tablet may cause a decrease in appetite which may further cause weight loss. You should monitor your weight regularly while on treatment with Aprezo 30mg Tablet. In case of significant weight loss, consult your doctor and consider stopping Aprezo 30mg Tablet.
How should Aprezo 30mg Tablet be taken?
Be sure to take Aprezo 30mg Tablet exactly as directed by your doctor. Your doctor will prescribe a low dose initially. This dose will be increased gradually after 6 days. Swallow the tablets whole with water. You can take it with or without food.
Can I take rifampicin along with Aprezo 30mg Tablet?
You should not take rifampicin if you are taking Aprezo 30mg Tablet. Rifampicin interferes with the working of Aprezo 30mg Tablet by decreasing its levels, making it less effective. As a result, you may not see any improvement after taking Aprezo 30mg Tablet.
What if I get pregnant during treatment with Aprezo 30mg Tablet?
In case you get pregnant while taking Aprezo 30mg Tablet, you should inform your doctor immediately. In fact, pregnancy should be avoided during treatment with this medicine. The reason being, according to animal studies, with Aprezo 30mg Tablet there may be a risk of baby loss or defects in unborn baby.
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References
Medscape. Apremilast. [Accessed 02 Apr. 2019] (online) Available from:
National Drug Monograph. Apermilast; 2015. [Accessed 02 Apr. 2019] (online) Available from:
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