Atrest 12.5 Tablet
Prescription Required
Product introduction
Atrest 12.5 Tablet is used to treat chorea (which is a movement disorder characterized by involuntary, jerky movements) associated with Huntington's disease. It balances dopamine levels, reducing movements and improving function. This helps it easier for the person to move and function better.
Atrest 12.5 Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication must not be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome, characterized by fever, muscle rigidity, and altered consciousness or seizures.
Some common side effects of this medicine include nausea, insomnia(difficulty sleeping), anxiety, fatigue, akathisia (restlessness and inability to stay still), and depression. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
Atrest 12.5 Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication must not be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience neuroleptic malignant syndrome, characterized by fever, muscle rigidity, and altered consciousness or seizures.
Some common side effects of this medicine include nausea, insomnia(difficulty sleeping), anxiety, fatigue, akathisia (restlessness and inability to stay still), and depression. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
Uses of Atrest Tablet
Benefits of Atrest Tablet
In Treatment of chorea (a movement disorder) associated with Huntington's disease
Chorea is a movement disorder characterized by involuntary, jerky movements that can be associated with Huntington's disease. Atrest 12.5 Tablet helps to treat these symptoms and also controls these jerky movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.
Side effects of Atrest Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Atrest
- Nausea
- Insomnia (difficulty in sleeping)
- Anxiety
- Fatigue
- Sleepiness
- Akathisia (inability to stay still)
- Depression
How to use Atrest Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Atrest 12.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Atrest Tablet works
Atrest 12.5 Tablet works by depleting the stores of certain chemical messengers (such as dopamine, serotonin, norepinephrine, and histamine) in the brain that helps in controlling body movements.
Safety advice
Alcohol
UNSAFE
Atrest 12.5 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Atrest 12.5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Atrest 12.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Atrest 12.5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Atrest 12.5 Tablet in patients with kidney disease. Please consult your doctor.
However, caution is advised in these patients.
However, caution is advised in these patients.
Liver
UNSAFE
Atrest 12.5 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
What if you forget to take Atrest Tablet?
If you miss a dose of Atrest 12.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- You have been prescribed Atrest 12.5 Tablet to help control movement disorders such as in Huntington’s disease.
- Be cautious while driving or doing anything that requires concentration as Atrest 12.5 Tablet can cause dizziness and sleepiness.
- Inform your doctor if you experience symptoms such as high fever, sweating, muscle stiffness, and faster breathing. These may be due to a rare side effect known as the neuroleptic malignant syndrome.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
- Do not stop taking Atrest 12.5 Tablet without talking to your doctor first as it may cause worsening of symptoms.
Fact Box
Chemical Class
Tetrahydroisoquinoline Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Monoamine depletor- Tetrabenazine
Patient concerns
User feedback
Patients taking Atrest 12.5 Tablet
Twice A Day
51%
Once A Day
34%
Thrice A Day
15%
What are you using Atrest Tablet for?
Huntington's *
62%
Others
38%
*Huntington's disease
How much was the improvement?
Average
42%
Poor
33%
Excellent
25%
What were the side-effects while using Atrest 12.5 Tablet?
No Side Effec*
100%
*No Side Effect
How do you take Atrest Tablet?
With food
100%
Please rate Atrest 12.5 Tablet on price
Expensive
67%
Average
33%
FAQs
Can Atrest 12.5 Tablet be crushed?
No, Atrest 12.5 Tablet should not be crushed, cut, or chewed. It needs to be swallowed as a whole. But if you cannot swallow the whole tablet, tell your doctor who will probably prescribe you another medicine.
Is Atrest 12.5 Tablet an antipsychotic?
Atrest 12.5 Tablet is not an antipsychotic. It belongs to the vesicular monoamine transporter 2 (VMAT2) inhibitor class of medicines. It works by changing the activity of some natural substances in the brain that affect muscles and nerves.
What is the most important information that I should know about Atrest 12.5 Tablet?
Atrest 12.5 Tablet may increase the risk of depression or suicidal thoughts in patients with Huntington’s disease. Huntington’s disease is an inherited disease that causes the progressive breakdown of nerve cells in the brain. Therefore, you should not take Atrest 12.5 Tablet if you have Huntington’s disease along with depression.
What should I avoid while taking Atrest 12.5 Tablet?
Sleepiness is a common side effect of Atrest 12.5 Tablet. Therefore, you should avoid driving or operating heavy machinery if you feel sleepy while taking Atrest 12.5 Tablet.
Can I stop taking Atrest 12.5 Tablet on my own?
No, you should not stop taking Atrest 12.5 Tablet suddenly, without talking to your doctor. Sudden discontinuation of the medicine may cause neuroleptic malignant syndrome. This can be characterized by high fever, stiff muscles, confusion, hallucinations, increased sweating, and very fast or uneven heart beat. Hence, to avoid such side effects your doctor will gradually reduce your dose.
Can I take alcohol while on Atrest 12.5 Tablet?
You should avoid alcohol since it may add to the sleepiness caused by Atrest 12.5 Tablet. Similarly, you should avoid taking medicines which cause sleepiness. If you are not sure about the effects of the medicine, consult with your doctor.
Does Atrest 12.5 Tablet affect blood pressure?
Yes, Atrest 12.5 Tablet may affect the blood pressure. In some patients it may decrease the levels of blood pressure. Along with that, one may experience dizziness, lightheadedness, and fainting while getting up quickly from a lying position (orthostatic hypotension). To avoid this problem, get out of bed slowly, rest your feet on the floor for a few minutes before standing up.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 480.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1337-38.
- Tetrabenazine. Washington, DC: Prestwick Pharmaceutical; 2008. [Accessed 19 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Tetrabenazine [Product Label]. Centuar Pharma. [Accessed 07 Aug. 2023]. (online) Available from:
Marketer details
Name: Centaur Pharmaceuticals Pvt Ltd
Address: CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Country of origin: India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Atrest 12.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Atrest 12.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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1 Strip
10.0 tablets in 1 strip
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