Atropine Sulphate Injection is used to treat bradycardia (slow heart rate). It helps to restore normal heartbeat in cardiac arrest cases. This injection is also given before general anesthesia to reduce saliva secretions. It even works as an antidote to some insecticide poisoning.
Atropine Sulphate Injection may be used in combination with other medicines to reverse the effect of muscle relaxants during surgery. It is given by your doctor or nurse, who will make sure you get the right amount. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
Common side effects of this medicine include blurred vision and fast heart rate. Dry mouth may also occur while using this medicine so, try to do frequent mouth rinses, maintain good oral hygiene and increase water intake.
Pregnant or breastfeeding women should also consult their doctor before taking this medicine. It is better to avoid this medication if you are suffering from any severe heart disease or urinary retention.
Bradycardia refers to a heart rate that is slower than the normal heart rate. Atropine Sulphate Injection helps to bring back the blood pressure within normal range. This relaxes the heart, treats decreased heart rate (bradycardia) and prevents any sudden fall of blood pressure or even serious complications that might have otherwise followed due to low blood pressure. It is given as an injection by a doctor or nurse in a hospital setup. It should not be self-administered. Follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Atropine Sulphate Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Atropine Sulphate
Injection site pain
How to use Atropine Sulphate Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Atropine Sulphate Injection works
Atropine Sulphate Injection is an anticholinergic medication. It works by blocking the activity of a chemical messenger (acetylcholine). This helps dry up secretions (saliva, sweat, etc.) from glands before surgery, increases a low heart rate and decreases intestinal contractions (spasms). It also works as an antidote in certain types of poisoning and reverses the side effects of certain muscle relaxing medicines.
Safety advice
Alcohol
UNSAFE
Atropine Sulphate Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Atropine Sulphate Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Atropine Sulphate Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Milk secretion may decrease.
Driving
UNSAFE
Atropine Sulphate Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Atropine Sulphate Injection should be used with caution in patients with kidney disease. Dose adjustment of Atropine Sulphate Injection may be needed. Please consult your doctor.
Liver
CAUTION
Atropine Sulphate Injection should be used with caution in patients with liver disease. Dose adjustment of Atropine Sulphate Injection may be needed. Please consult your doctor.
What if you forget to take Atropine Sulphate Injection?
If you miss a dose of Atropine Sulphate Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
I'm having trouble like bradycardia, in the year 1995, it was tracicardia. Recent medical test says that it is bradycardia. Presently taking allopathic medicine. Want to change to homoeopathy.
Dr. Saurav Arora
Homeopathy
Please send your complete reports, and treatment details
Q. What is Atropine Sulphate Injection used for in an emergency?
Atropine Sulphate Injection is used in emergency situations when the heart beats too slowly, as an antidote to insecticide or mushroom poisoning. It can be used as part of the premedication before general anesthesia. It is also used in combination with other drugs to reverse the effect of muscle relaxants used during surgery.
Q. Who should not take Atropine Sulphate Injection?
Inform your doctor if you have high blood pressure, lung disease, stomach ulcers, liver problems, and thyroid disorders before taking this medicine.
Q. Where is Atropine Sulphate Injection injected?
This medicine is injected into a muscle, under the skin, or as an infusion into a vein. A healthcare provider will give you this injection in a hospital setting only.
Q. What happens if you are given Atropine Sulphate Injection in excess?
Some of the signs of overdose are dilation of the pupils, difficulty in swallowing, hot dry skin, flushing, inability to pass urine, rapid breathing, increased heart rate, and hyperactivity. However, this rarely happens as Atropine Sulphate Injection is administered under the care of a highly trained doctor. If you suspect you have been given this medicine in excess, you should tell the doctor immediately.
Q. What should I avoid while receiving Atropine Sulphate Injection?
Avoid becoming overheated or dehydrated during exercise and in hot weather. Atropine Sulphate Injection can decrease sweating and you may be more prone to heatstroke. Drink lots of fluids to stop fluid loss.
Q. Can Atropine Sulphate Injection be given to pregnant women?
No, Atropine Sulphate Injection should not be given during pregnancy since the medicine may cross the placental barrier and may cause tachycardia (rapid heartbeat) in the fetus.
Q. Does Atropine Sulphate Injection cause dryness in the mouth?
Yes, dry mouth is a common side-effect of this medicine. Frequent mouth rinses, good oral hygiene, increased water intake and sucking sugarless candy may help.
Q. Does Atropine Sulphate Injection make you sleepy?
This medicine may cause drowsiness and blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Do not drive until your pupils are no longer dilated.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Brown JH, Laiken N. Muscarinic Receptor Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 225-30.
Medscape. Atropine. [Accessed 27 Mar. 2019] (online) Available from:
Atropine. Lake forest, Illinois: Hospira, Inc.; 1960 [revised Oct. 2015]. [Accessed 28 Mar. 2019] (online) Available from:
Atropine Sulfate Injection [Prescribing Information]. Berkeley Heights, NJ: Hikma Pharmaceuticals USA Inc.; 2020. [Accessed 20 Feb. 2024] (online) Available from:
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