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PhD (Pharmacology), PGDPRA
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MD Pharmacology, MBBS
Last updated
16 Dec 2024 | 01:05 AM (IST)

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Product introduction

Avonza Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Avonza Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine should be taken in an empty stomach, preferably at bedtime for better efficacy. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine must not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it.

The most common side effects of this medicine are impaired concentration, abnormal dreams, headache, nausea, weakness and fatigue, nasal congestion, diarrhea, rash, dizziness, trouble sleeping, pain, depression, and cough. These are usually not serious and go away within 2-4 weeks of treatment, however, inform your doctor if they bother you or do not go away. As it can also make you feel dizzy or drowsy, it is advised to avoid driving. In addition to that, avoid alcohol consumption as it may increase the intensity of the side effects.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any kidney, liver, or other diseases. Your doctor may suggest some laboratory tests before and during the treatment to check your blood counts, liver and kidney functioning, and other health and mental conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods to prevent transmission of HIV during intercourse.


Uses of Avonza Tablet

Benefits of Avonza Tablet

In Treatment of HIV infection

Avonza Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this medicine as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of medicines and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.

Side effects of Avonza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Avonza

  • Joint pain
  • Pneumonia
  • Muscle pain
  • Increased triglyceride level in blood
  • Elevated levels of serum amylase
  • Blood in urine
  • Increased transaminase level in blood
  • Cough
  • Impaired concentration
  • Abnormal dreams
  • Headache
  • Dizziness
  • Nausea
  • Insomnia (difficulty in sleeping)
  • Weakness
  • Depression
  • Diarrhea
  • Rash
  • Pain
  • Fever
  • Decreased white blood cell count (neutrophils)
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Back pain
  • Abdominal pain
  • Anxiety
  • Vomiting
  • Indigestion

How to use Avonza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Avonza Tablet is to be taken empty stomach.

How Avonza Tablet works

Avonza Tablet is a combination of three antiviral medicines: Lamivudine, Tenofovir disoproxil fumarate and Efavirenz. They work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Avonza Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Avonza Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Avonza Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Avonza Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Avonza Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Avonza Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Avonza Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Avonza Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Avonza Tablet?

If you miss a dose of Avonza Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Avonza Tablet
₹71.47/Tablet
Vianca Tablet
Emcure Pharmaceuticals Ltd
₹60.39/tablet
16% cheaper
Vianca Tablet
Emcure Pharmaceuticals Ltd
₹60.37/tablet
16% cheaper
Epelar 300mg/300mg/400mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹98.73/tablet
38% costlier
Trilavir Mini Tablet
Laurus Labs Limited
₹64.03/tablet
10% cheaper

Quick tips

  • Avonza Tablet is a combination of three medicines which slows down or stops the progression of HIV infections.
  • Take it on an empty stomach, preferably at bedtime, to reduce side effects.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Avonza Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Avonza Tablet can cause birth defects. Use effective contraception while taking Avonza Tablet and 12 weeks after stopping it.
  • It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
  • Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Do not stop taking Avonza Tablet without your doctor’s advice.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

arrow
i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner
hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero
Dr. Atula Gupta
Dermatology
You still need to be on ART even if the viral load is undetectable
arrow

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Tenofovir Disoproxil Fumarate+Lamivudine+Efavirenz. Place of publication: Mylan Laboratories Limited; Sep. 2014. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Lamivudine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 24 Jun. 2018]. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Tenofovir disoproxil. Limassol, Cyprus: Remedica Ltd.; 2018. [Accessed 09 Apr. 2019] (online) Available from:External Link
  4. Efavirenz. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2014 [revised 10 Dec. 2018]. [Accessed 09 Apr. 2019. 2019] (online) Available from:External Link
  5. CiplaMed. Tenofovir Disoproxil Fumarate, Lamivudine and Efavirenz [Prescribing Information]. [Accessed 14 Aug. 2024] (online) Available from: External Link

Marketer details

Name: Mylan Pharmaceuticals Pvt Ltd - A Viatris Company
Address: Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103
Country of origin: United states

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