Avplex 30mg Capsule
Prescription Required
Product introduction
Avplex 30mg Capsule is used in the treatment of moderate to severe plaque psoriasis which is a type of skin condition. This medicine is used when other conventional treatments cannot be used or if the patient is not responsive or intolerant to any of these treatments.
Avplex 30mg Capsule can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. You may need to monitor your weight regularly while taking the medicine as it may cause weight loss.
Using this medicine may cause few common side effects such as nausea, diarrhea, vomiting, headache, and upper respiratory tract infection. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know all the other medicines you are taking. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.
Uses of Avplex Capsule
- Plaque psoriasis
Benefits of Avplex Capsule
In Plaque psoriasis
Plaque psoriasis is the most common form of psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Avplex 30mg Capsule reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Avplex Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Avplex
- Diarrhea
- Nausea
- Vomiting
- Headache
- Upper respiratory tract infection
How to use Avplex Capsule
Take this medicine in the dose and duration as advised by your doctor. Avplex 30mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Avplex Capsule works
Avplex 30mg Capsule is a phosphodiesterase 4 (PDE4) inhibitors. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of these conditions.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Avplex 30mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Avplex 30mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Avplex 30mg Capsule during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Avplex 30mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Avplex 30mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Avplex 30mg Capsule may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Avplex 30mg Capsule is safe to use in patients with liver disease. No dose adjustment of Avplex 30mg Capsule is recommended.
What if you forget to take Avplex Capsule?
If you miss a dose of Avplex 30mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Avplex 30mg Capsule is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
- Monitor your weight regularly as Avplex 30mg Capsule may cause weight loss.
- Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
- Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes or unexplained weight loss.
Fact Box
Chemical Class
Isoindole Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Phosphodiesterase-IV inhibitors (PsA & PSO)
Patient concerns
FAQs
Is Avplex 30mg Capsule an immunosuppressant?
No, Avplex 30mg Capsule is not an immunosuppressant. It belongs to a class of medicines known as phosphodiesterase 4 inhibitors (PDE4) which work by blocking the activity of PDE4. PDE4 is found in inflammatory cells and blocking it helps in reducing the molecules responsible for inflammation.
How long does it take for Avplex 30mg Capsule to work?
Avplex 30mg Capsule is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term treatment and may take about 16 weeks to show an improvement.
Can Avplex 30mg Capsule cause depression?
Yes, Avplex 30mg Capsule may cause depression as a side effect. The patient may also develop suicidal thoughts. It should be avoided in patients with a history of depression. In case you develop any of these symptoms, consult your doctor immediately or ask your friends or relatives to help seek medical advice.
Does Avplex 30mg Capsule cause weight reduction?
Yes, Avplex 30mg Capsule may cause a decrease in appetite which may further cause weight loss. You should monitor your weight regularly while on treatment with Avplex 30mg Capsule. In case of significant weight loss, consult your doctor and consider stopping Avplex 30mg Capsule.
How should Avplex 30mg Capsule be taken?
Be sure to take Avplex 30mg Capsule exactly as directed by your doctor. Your doctor will prescribe a low dose initially. This dose will be increased gradually after 6 days. Swallow the tablets whole with water. You can take it with or without food.
Can I take rifampicin along with Avplex 30mg Capsule?
You should not take rifampicin if you are taking Avplex 30mg Capsule. Rifampicin interferes with the working of Avplex 30mg Capsule by decreasing its levels, making it less effective. As a result, you may not see any improvement after taking Avplex 30mg Capsule.
What if I get pregnant during treatment with Avplex 30mg Capsule?
In case you get pregnant while taking Avplex 30mg Capsule, you should inform your doctor immediately. In fact, pregnancy should be avoided during treatment with this medicine. The reason being, according to animal studies, with Avplex 30mg Capsule there may be a risk of baby loss or defects in unborn baby.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Medscape. Apremilast. [Accessed 02 Apr. 2019] (online) Available from:
- National Drug Monograph. Apermilast; 2015. [Accessed 02 Apr. 2019] (online) Available from:
- Apremilast [Prescribing Information]. Thousand Oaks, CA: Amgen Inc.; 2021. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Monark Biocare Pvt Ltd
Address: SCF-245, 2nd Floor, Motor Market, Manimajra, Chandigarh – 160101 , India
Country of origin: India
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