Azanol Tablet belongs to a group of medicines called immunosuppressants. It is used with other medicines to prevent your body from rejecting an organ (such as a kidney, heart, or liver) after a transplant. It is also used in the treatment of rheumatoid arthritis.
The dose of Azanol Tablet and how often you need to take it will depend on whether you have had a transplant or are being treated for rheumatoid arthritis. Follow your doctor’s instructions on this. You can take it with or without food. Take the medicine regularly to get the most benefit and keep taking it even if you feel well. If you stop taking it, the risk of organ rejection may increase, and if you're using it for rheumatoid arthritis, your symptoms may not improve.
The most common side effects of Azanol Tablet are nausea and reduction of white blood cells and bone marrow function. Because it suppresses your immune system, you may catch infections easily. There is also an increased risk of developing some cancers for this reason. You should ask your doctor about side effects that may require urgent medical attention.
Azanol Tablet can cause birth defects and miscarriages, so do not take it if you are pregnant, planning to become pregnant, or breastfeeding. You should talk to your doctor before taking this medicine if you have any signs of infection or any unexpected bruising or bleeding. Let your doctor also know what other medications you are taking, as some may interact with this medicine and affect the way it works. You will have regular tests to check for any changes in the number of your blood cells.
Azanol Tablet works by blocking the action of some chemicals that cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it prevents future harm as well as improves your symptoms.
In Prevention of organ rejection in transplant patients
Azanol Tablet is an immunosuppressive agent that lowers your immune response and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine may be used in combination with other medicines to suppress the immune system and help your body accept the new organ.
Side effects of Azanol Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Azanol
Viral infection
Fungal infection
Bacterial infection
Decreased white blood cell count
Bone marrow disorder
Increased bleeding tendency
Nausea
How to use Azanol Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Azanol Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Azanol Tablet works
Azanol Tablet is an immunosuppressant. It reduces the action of the body's defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain joint diseases.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Azanol Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Azanol Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Azanol Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Azanol Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Azanol Tablet should be used with caution in patients with kidney disease. Dose adjustment of Azanol Tablet may be needed. Please consult your doctor. Use of Azanol Tablet is not recommended in patients with serious kidney disease.
Liver
CAUTION
Azanol Tablet should be used with caution in patients with liver disease. Dose adjustment of Azanol Tablet may be needed. Please consult your doctor. Use of Azanol Tablet is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while you are taking this medicine.
What if you forget to take Azanol Tablet?
If you miss a dose of Azanol Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You may have to take additional medications along with Azanol Tablet for better relief of symptoms.
Avoid contact with people who have a cold, flu, or other contagious illness. Notify your doctor if you have any signs of infection, such as a fever or sore throat.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Fact Box
Chemical Class
Nucleoside Analog, and Purines
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- Purine analogs
Interaction with drugs
Taking Azanol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
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Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason?
Suffering from type 2 diabetes rheumatoid arthritis , asthma which medicine should I use
Dr. Jagruti Mahendra Parikh
Diabetology
Most of the diabetic drugs can be given in Rheumatoid arthritis and asthma patients however however steroids treatments is given many times in asthma and Rhumatoid arthritis should be given with very caution in diabetic patients if indicatedMost suitable some times are insulin injections
Severe Joint pain in left hand wrist, elbow, shoulder and neck joint. Took some TEST and reports attached. Provided tablets are not killing the pain. Kindly help and guide us in right way. Attached Anti CCT TEST repory
Vipul Aggarwal
Looks like a case of rheumatoid arthritis.Kindly consult a rheumatologist asap
What is Azanol Tablet prescribed for? How does it work?
Azanol Tablet is an immunosuppressant, which means that it acts by suppressing the immune defense system of the body. Your immune defense system helps to protect you against infections. However, sometimes your immune defense system can become overactive and can cause illness. Azanol Tablet is used in combination with other medicines to treat the conditions caused by this abnormal activity of the immune system. It is used to prevent the rejection of transplanted organs, like the kidney, heart, or liver. It is also used to treat rheumatoid arthritis.
How long do I need to take Azanol Tablet?
The duration varies from person to person, as it is prescribed depending on the patient’s medical condition.
Is breastfeeding safe during Azanol Tablet treatment?
No, breastfeeding should be avoided while on Azanol Tablet, since it may harm the baby and cause serious side effects.
I have just started taking Azanol Tablet. What are the long-term side effects? Is there anything I should be looking out for?
Being an immunosuppressant, Azanol Tablet can increase the chances of severe infections and decrease blood cell counts, and malignancy. You should inform your doctor immediately if you notice any infection or fever, unexpected bruising or bleeding, black tarry stools, or blood in the urine or stools. Let your doctor know if you notice any new skin sore or lump, new marks on the skin, or any change in the marks that were previously present.
Do I need any special tests while I am on Azanol Tablet?
Azanol Tablet reduces the production of white blood cells, making you more vulnerable to infections, and can sometimes affect the liver. These side effects can be monitored by regular blood tests. Therefore, during the first 8 weeks of the treatment, your doctor may recommend weekly blood tests to monitor complete blood counts, including platelet counts. The frequency can later be reduced to monthly or at least once every 3 months.
Can Azanol Tablet cause cancer?
Azanol Tablet may increase the chance of developing certain cancers like skin cancer, cancer of the lymph system (lymphoma), cancer of soft tissues (sarcomas), and cervical cancer. To prevent the risk of skin cancer, avoid prolonged exposure to sunlight and wear protective clothing, sunglasses, and sunscreen. Tell your doctor immediately if you notice any changes in your skin or any lumps or masses anywhere on your body.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1013-14.
Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 629-30.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 113-15.
Azathioprine [Prescribing Information]. San Diego, California: Prometheus Laboratories Inc.; 2014. [Accessed 06 Apr. 2019] (online) Available from:
The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.