Barilup 2mg Tablet is used in combination with Remdesivir for the treatment of coronavirus disease (COVID-19) in hospitalized adults.
Barilup 2mg Tablet may be prescribed by itself or in combination with another drug. The tablets can be taken with or without food, and it’s best to take them at the same time each day. Your dose will depend on your condition and what other medicines you’re taking. You should use it as your doctor tells you to. Don’t stop taking this medicine unless your doctor tells you to because your condition could get worse.
The most common side effects of Barilup 2mg Tablet include throat and nose infections, nausea, and viral infection. You may also get cold sores, feel sick, or have symptoms of a cold like stuffy nose, sneezing, and sore throat. There are other less common side effects, some serious, including blood clots and tears in the stomach or intestine wall. These need urgent medical attention. If you have any worries about side effects, talk to your doctor.
You may need blood tests before you’re given this medicine, and you shouldn’t start taking it if you have any infection. Make sure you talk to your doctor before beginning treatment if you have, or have ever had, tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Barilup 2mg Tablet can make you more likely to get infections or may worsen any current infections, so avoid contact with people who have things you might catch (such as chickenpox, measles, and flu). This medicine is not suitable for children under 18 years old, and you shouldn’t use it if you’re pregnant or breastfeeding unless your doctor feels the benefit is greater than the risk. Your doctor may need to examine you regularly.
Uses of Barilup Tablet
Treatment of Coronavirus disease (COVID-19)
Benefits of Barilup Tablet
In Treatment of Coronavirus disease (COVID-19)
Coronavirus disease (Covid-19) is a highly infectious disease caused by a coronavirus strain named SARS-CoV2. The most common symptoms are fever, cough, loss of taste or smell, breathing difficulty, nasal congestion, and diarrhea among others. Barilup 2mg Tablet helps alleviate these symptoms but must be used only under medical supervision.
Side effects of Barilup Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Barilup
Upper respiratory tract infection
Urinary tract infection
Bronchitis (inflammation of the airways)
How to use Barilup Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Barilup 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Barilup Tablet works
Barilup 2mg Tablet is a Janus kinase (JAK) inhibitor that inhibits the activity of selective JAK1 and JAK2 enzymes, which interfere with the JAK-STAT signaling pathway (a chain of protein-cell interactions, involved in processes such as immunity, cell division, cell death, and tumor formation).
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Barilup 2mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Barilup 2mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Barilup 2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Barilup 2mg Tablet does not usually affect your ability to drive.
Kidney
UNSAFE
Barilup 2mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor. Barilup 2mg Tablet is not recommended for adult patients with patients with end stage renal disease (ESRD).
Liver
SAFE IF PRESCRIBED
Barilup 2mg Tablet is safe to use in patients with liver disease. No dose adjustment of Barilup 2mg Tablet is recommended. Barilup 2mg Tablet may not be recommended in patients with severe liver disease due to lack of information and research. Therefore, it is important to consult the doctor.
What if you forget to take Barilup Tablet?
If you miss a dose of Barilup 2mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Your doctor may order regular blood tests to monitor your liver function, kidney function, blood counts, and cholesterol level.
Before starting treatment with this medication, your doctor may order a TB (tuberculosis) skin test and a chest X-ray.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Fact Box
Chemical Class
Pyrrolo Pyrimidine Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Janus kinase inhibitors
Patient concerns
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Neurology
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Obstetrics and Gynaecology
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Can I take Barilup 2mg Tablet if I have liver problems?
Inform your doctor if you have liver problems before starting Barilup 2mg Tablet. This is done because, in some cases, Barilup 2mg Tablet may cause an increase in liver enzymes. Therefore, your liver function needs to be investigated before starting Barilup 2mg Tablet. Although Barilup 2mg Tablet can be given to patients with mild to moderate liver function impairment, it should not be prescribed to patients with severe liver impairment.
Can Barilup 2mg Tablet cause cancer?
Barilup 2mg Tablet may increase the chances of developing certain cancers (lymphoma and other cancers, including skin cancers) by affecting the immune system's functioning. Hence, inform your doctor if you have ever had or have any type of cancer.
Do I need to do any investigations before starting Barilup 2mg Tablet?
You may need to get your blood tests done before you start Barilup 2mg Tablet or while taking it. Blood tests are done to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol), or high levels of liver enzymes. It also helps to ensure that treatment with Barilup 2mg Tablet is not causing problems. In addition to this, your doctor may advise you to get tested for tuberculosis before starting Barilup 2mg Tablet, as using this medicine may make an existing infection worse.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Baricitinib [Prescribing Information]. Indianapolis, IN: Eli Lilly and Company; 2022. [Accessed 16 Oct. 2024] (online) Available from:
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