Bavencio Injection is a medicine used for treatment of urinary bladder cancer that has metastasized (spread to other parts) or has reached the advanced stage in adults and children aged above 12 years. It restores those immune responses in the body that stop cancer growth.

Bavencio Injection is given as an injection by a healthcare professional. For it to be effective, complete the course of the medicine and do not discontinue even if you get better until the course is completed.

Some common side effects of this medicine include fatigue, nausea, diarrhea, decreased appetite, and muscle pain amongst others. These are usually mild and go away with time. However, if they persist or get worse, let the doctor know.

Before receiving the medicine, you should let your doctor if you have ever had an allergic reaction to any medicine. Also tell your doctor if you have any problems with your heart, kidneys, or liver. Some other medicines may react with this medicine, so let your doctor know of all the medication you are taking. Pregnant or breastfeeding should consult their doctors first before receiving this medicine.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Bavencio Injection

Treatment of Urinary bladder cancer

Benefits of Bavencio Injection

In Treatment of Urinary bladder cancer

Bavencio Injection helps to treat urinary bladder cancer. It kills the cancer cells by stimulating the immune system of our body. It prevents progression of the disease to advanced stages of cancer and also reduces the chances of recurrence of the cancer. It is given as an injection by a doctor or nurse and should not be self-administered.

Side effects of Bavencio Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bavencio

Fatigue
Musculoskeletal (bone, muscle or joint) pain
Diarrhea
Nausea
Infusion site reaction
Rash
Decreased appetite
Peripheral edema
Urinary tract infection
High blood pressure
Mucositis
Hand-foot syndrome
Voice change
Decreased level of thyroid hormones
Liver toxicity
Coughing up blood
Breathlessness
Abdominal pain
Headache

How to use Bavencio Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bavencio Injection works

Bavencio Injection is a type of immunotherapy. It activates the body's immune system to fight cancer cells. Avelumab targets and blocks a protein (PD-L1) found on the surface of certain immune cells. Blocking PD-L1 activates the immune cells to find and kill cancer cells.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bavencio Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Bavencio Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Bavencio Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

SAFE

Bavencio Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Bavencio Injection is safe to use in patients with kidney disease. No dose adjustment of Bavencio Injection is recommended.

Liver

SAFE IF PRESCRIBED

Bavencio Injection is safe to use in patients with liver disease. No dose adjustment of Bavencio Injection is recommended.

What if you forget to take Bavencio Injection?

If you miss a dose of Bavencio Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Do not receive any immunization or vaccination without your doctor’s approval while taking Bavencio Injection.
You may be at risk of infection, so try to avoid crowds or people with colds, and immediately report fever or any other signs of infection to your health care provider.
Inform your doctor immediately if you notice signs or symptoms of skin rash, itchy skin, a rash with tiny spots and bumps, reddening of the skin.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Use contraceptives, and do not conceive a child (get pregnant) while taking Bavencio Injection. Barrier methods of contraception, such as condoms, are recommended.
Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.
Do not drive or use machines after you have received Bavencio Injection since you might feel tired or dizzy.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Patient concerns

Swelling in urinary bladder and uterus

Dr. Megha Tuli

Obstetrics and Gynaecology

Kindly get an ultrasound of abdomen done

I am a diabetic and using Gluconorm PG-2 tablet since 3 years. The results for controlling diabetic is good. However, I have read some where that using Gluconorm PG-2 tablet for more than a year is likely to have bladder cancer. Is it correct? Can your prescribe any alternative medicine.

Dr. Ashwin Porwal

Internal Medicine

its the pioglitazone that can cause bladder cancerbut its frequency is too less

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Bavencio (Avelumab) [Product Information]; 2021. [Accessed 16 Nov. 2022] (online) Available from:
Avelumab [Prescribing Information]. Rockland, MA: : EMD Serono, Inc.; 2022. [Accessed 16 Nov. 2022] (online) Available from:
Avelumab [Summary of Product Characteristics]. Modugno, Italy: Merck Serono S.p.A.; 2020. [Accessed 16 Nov. 2022] (online) Available from:

Marketer details

Name: Merck Ltd

Address: L-2, J.R. Complex, Gate No. 4, Village Mandoli, Delhi-110 093, India

Country of origin: Swaziland

MRP

₹146800

Inclusive of all taxes

10.0 ml in 1 vial

SOLD OUT

Notify me

We provide you with authentic, trustworthy and relevant information

Have issue with the content?

Bavencio Injection

Product introduction