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MDS, BDS
Reviewed By
MBA, MD Pharmacology
Last updated
17 Dec 2024 | 01:02 AM (IST)

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Bdbrut Capsule


Product introduction

Bdbrut Capsule is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). It is also used in chronic lymphocytic leukaemia who have received at least one prior therapy.

Bdbrut Capsule is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your response to treatment. Your doctor may get regular blood tests to check number of blood cells during treatment with this medicine. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections.  It may cause headache, diarrhea, and nausea as its side effects.


Side effects of Bdbrut Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bdbrut

  • Fever
  • Headache
  • Fatigue
  • Musculoskeletal (bone, muscle or joint) pain
  • Rash
  • Anemia (low number of red blood cells)
  • Bruising
  • Muscle spasm
  • Hemorrhage
  • Pneumonia
  • Cough
  • Diarrhea
  • Stomatitis (Inflammation of the mouth)
  • Nausea
  • Low blood platelets
  • Decreased white blood cell count (neutrophils)
  • Dry eye
  • High blood pressure
  • Weight loss
  • Urinary tract infection
  • Peripheral edema
  • Subdural hematoma
  • Second primary malignancies

How to use Bdbrut Capsule

Take this medicine in the dose and duration as advised by your doctor. Bdbrut Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Bdbrut Capsule works

Bdbrut Capsule is a Bruton's tyrosine kinase inhibitor. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bdbrut Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Bdbrut Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CAUTION
Bdbrut Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Bdbrut Capsule may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Bdbrut Capsule should be used with caution in patients with kidney disease. Dose adjustment of Bdbrut Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Bdbrut Capsule should be used with caution in patients with liver disease. Dose adjustment of Bdbrut Capsule may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Bdbrut Capsule
₹237.73/Capsule
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Nitib 140mg Capsule
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Ibrushil 140mg Capsule
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Ibrukem Capsule
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₹297.17/capsule
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Imbruvica 140mg Capsule
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₹3356.53/capsule
1312% costlier

Quick tips

  • Take it at the same time every day, either with or without food.
  • It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood.
  • Take it at the same time every day, either with or without food.
  • It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood.

Fact Box

Chemical Class
Diphenylethers Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Bruton's tyrosine kinase (BTK) inhibitors

Interaction with drugs

Taking Bdbrut with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of bleeding. Talk to your doctor if you notice any unusual symptoms.
Concurrent use may increase the risk of bleeding. Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Ibrutinib may raise blood levels of Fluvastatin. Talk to your doctor if you notice any unusual symptoms.
Ibrutinib may raise blood levels of Methotrexate. Talk to your doctor if you notice any unusual symptoms.
No significant interaction is generally observed. Talk to your doctor regarding effective contraception during the simultaneous use of these medicines.

Patient concerns

arrow
Symptoms of lymphoma And blood cancer
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms could be like fever, weight loss, anorexia, lymphadenopathy.
What is t-cell all ??? And treatment This is my mother first born mero report Now the blast is less then 5% after 1 month treatment
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is blood cancerShe is in remission
arrow

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  2. Ibrutinib. Beerse Belgium: Janssen Pharmaceutica NV; [Accessed on 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: BDR Pharmaceuticals Internationals Pvt
Address: 407-408, Sharda Chambers, New Marine Lines, Mumbai 400 020 (Maharashtra), New Marine Lines, Marine Lines, Mumbai, Maharashtra 400020
Country of origin: India

7132
Inclusive of all taxes
MRP7200  1% OFF
30.0 capsules in 1 bottle
SOLD OUT

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