Besponsa 1mg Injection
Prescription Required
Product introduction
Besponsa 1mg Injection is a CD22-directed antibody-drug conjugate (ADC) used to treat adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL).
Besponsa 1mg Injection is given as an injection into veins by the healthcare provider. The dose will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or in more than the recommended dose can cause very serious side effects. It may take several weeks or months to see or feel the benefits but do not stop taking it unless your doctor tells you to.
This medicine's most common side effects include decreased blood cells (red cells, white cells, and platelets), infection, fatigue, hemorrhage, fever, nausea, headache, increased liver enzymes, and abdominal pain. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history of bleeding disorders, heart or liver disease, radiation treatment, or any other infection. Many other medicines can affect, or be affected by, this medicine, so let your doctor know about all the medications you are using. Inform the doctor immediately if you notice unusual bruising or bleeding, have dark, tarry, or bloody stools, and sore throat. This medicine reduces the number of blood cells in your blood, thereby increasing susceptibility to infections. Regular blood tests are required to check your blood cells along with the kidney, liver, and heart function during the treatment with this medicine. Effective contraception by males and females during the treatment with this medicine is important to avoid pregnancy.
Besponsa 1mg Injection is given as an injection into veins by the healthcare provider. The dose will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it the wrong way or in more than the recommended dose can cause very serious side effects. It may take several weeks or months to see or feel the benefits but do not stop taking it unless your doctor tells you to.
This medicine's most common side effects include decreased blood cells (red cells, white cells, and platelets), infection, fatigue, hemorrhage, fever, nausea, headache, increased liver enzymes, and abdominal pain. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.
Inform your doctor if you have a medical history of bleeding disorders, heart or liver disease, radiation treatment, or any other infection. Many other medicines can affect, or be affected by, this medicine, so let your doctor know about all the medications you are using. Inform the doctor immediately if you notice unusual bruising or bleeding, have dark, tarry, or bloody stools, and sore throat. This medicine reduces the number of blood cells in your blood, thereby increasing susceptibility to infections. Regular blood tests are required to check your blood cells along with the kidney, liver, and heart function during the treatment with this medicine. Effective contraception by males and females during the treatment with this medicine is important to avoid pregnancy.
Uses of Besponsa Injection
- Acute lymphoblastic leukemia
Benefits of Besponsa Injection
In Acute lymphoblastic leukemia
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Besponsa 1mg Injection kills or stops the growth of cancer cells and prevents the multiplication of cancer cells. It is a potent and very toxic medicine, and you should discuss its risks and benefits with your doctor. Avoid drinking alcohol during the treatment with this drug and drink plenty of water to stay hydrated.
Side effects of Besponsa Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Besponsa
- Low blood platelets
- Decreased white blood cell count (neutrophils)
- Infection
- Anemia (low number of red blood cells)
- Decreased white blood cell count (lymphocytes)
- Fatigue
- Hemorrhage
- Fever
- Nausea
- Headache
- Febrile neutropenia
- Increased transaminase level in blood
- Abdominal pain
- Increased gamma-glutamyltransferase
- Increased bilirubin in the blood
How to use Besponsa Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Besponsa Injection works
Besponsa 1mg Injection contains Inotuzumab Ozogamicin, an antineoplastic agent that treats relapsed or refractory CD22-positive B cell precursor acute lymphoblastic leukaemia (ALL) in adults. targets CD22 antigen expressed on immature B-cell lymphocytes and blocks further growth of tumor cells. This medicine restores normal blood counts and helps achieve complete remission from the disease.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Besponsa 1mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Besponsa 1mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Besponsa 1mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Besponsa 1mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Besponsa 1mg Injection in patients with kidney disease. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Besponsa 1mg Injection is safe to use in patients with liver disease. No dose adjustment of Besponsa 1mg Injection is recommended.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Besponsa 1mg Injection
₹319935/Injection
Inonza 1mg Injection
Pfizer Ltd
₹330000/injection
same price
Quick tips
- Your doctor may monitor your blood counts and liver before you start taking Besponsa 1mg Injection and regularly throughout your treatment.
- Males and females of reproductive potential should use effective contraception during the treatment and for at least five and eight months respectively after the last dose.
- Avoid breastfeeding during the treatment and for two months after the last dose.
- Besponsa 1mg Injection can make you feel dizzy for the first few days. Rise slowly if you have been sitting or lying down for a long time.
- After starting the treatment with Besponsa 1mg Injection, you may be at risk of infection; so, try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Interaction with drugs
Taking Besponsa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Voriconazole with Inotuzumab Ozogamacin.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Voriconazole with Inotuzumab Ozogamacin.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Fluconazole with Inotuzumab Ozogamacin.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Efavirenz with Inotuzumab Ozogamacin.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Fluconazole with Inotuzumab Ozogamacin.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.Marketer details
Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: United states
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Besponsa 1mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Besponsa 1mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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1.0 Injection in 1 vial
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