Biosulin R 40IU Injection is a short-acting insulin used to treat type 1 and type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels after meals. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Biosulin R 40IU Injection is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 20-30 minutes before a meal. Do not stop taking it unless your doctor tells you to. It is only a part of the treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.

Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.

The most common side effect of this medicine include low blood sugar levels (hypoglycemia), injection site reactions, cold sweats, anxiety, shakiness, hunger, rapid heartbeat, headache, and nervousness. It may be seen if you do not eat right after a dose of this fast-acting insulin. To prevent this, it is important to always inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Some people gain weight while taking insulin.

Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver, or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.

Uses of Biosulin R Injection

Diabetes

Benefits of Biosulin R Injection

In Diabetes

Biosulin R 40IU Injection is a short-acting type of insulin that is usually used along with other diabetes medication for controlling blood sugar levels. It replaces the insulin that is normally produced in the body. This helps the glucose get into your muscle and fat cells so your body can use it for energy. It also decreases glucose production in the liver.

Lowering of blood sugar level helps reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Learn exactly how, where, and when to inject this insulin for it to be most effective. Take it regularly along with proper diet and exercise for a normal, healthy life.

Side effects of Biosulin R Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Biosulin R

Hypoglycemia (low blood glucose level)
Weight gain
Injection site reactions (pain, swelling, redness)
Cold sweat
Anxiety
Shakiness
Hunger pangs
Fast heart rate
Headache
Nervousness

How to use Biosulin R Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Biosulin R Injection works

Biosulin R 40IU Injection is a short-acting insulin, which starts working within 30 minutes after injection. It works similar to the insulin produced by the body. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Biosulin R 40IU Injection.

Pregnancy

SAFE IF PRESCRIBED

Biosulin R 40IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Biosulin R 40IU Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Biosulin R 40IU Injection should be used with caution in patients with kidney disease. Dose adjustment of Biosulin R 40IU Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.

Liver

CAUTION

Biosulin R 40IU Injection should be used with caution in patients with liver disease. Dose adjustment of Biosulin R 40IU Injection may be needed. Please consult your doctor.
Regular monitoring of glucose levels is recommended for dose adjustment.

What if you forget to take Biosulin R Injection?

If you forget to take Biosulin R 40IU Injection, your blood sugar may get too high (hyperglycemia). Take it as soon as you remember. If it's time for your next dose then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Biosulin R 40IU Injection

₹148/Injection

Huminsulin R 40IU/ml Injection

Eli Lilly and Company India Pvt Ltd

₹174/injection

14% costlier

Humarap 40IU/ml Injection

Cadila Pharmaceuticals Ltd

₹178.3/injection

17% costlier

Insulin (Nnd) 40IU/ml Injection

Novo Nordisk India Pvt Ltd

₹3.83/injection

97% cheaper

Newsulin 40IU Injection

Wockhardt Ltd

₹158.4/injection

4% costlier

New Wosulin R Injection

Wockhardt Ltd

₹196.71/injection

29% costlier

View all substitutes

Quick tips

Take it 20 to 30 minutes before a meal.
Hypoglycemia (low blood sugar level) is a common side-effect. Learn how to identify and manage its symptoms (sweating, rapid heartbeat, weakness, blurry vision, headache) and teach your family as well.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Opened vials/cartridges are good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).

Fact Box

Chemical Class

Insulin analogue

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Human insulin- short acting

Patient concerns

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Physician

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FAQs

Will I need Biosulin R 40IU Injection for the rest of my life?

If you are a type 1 diabetes patient, then yes, you have to take Biosulin R 40IU Injection for the rest of your life because your body is unable to produce sufficient insulin. Therefore, you would need Biosulin R 40IU Injection as an external source of insulin. However, if you are a type 2 diabetes patient, sometimes your doctor may ask you to stop Biosulin R 40IU Injection if you are able to manage your diabetes with proper exercise, diet and oral medicines.

Can Biosulin R 40IU Injection be used with other diabetes medicine?

Yes, Biosulin R 40IU Injection can be used alone or in combination with other diabetes medicines like long-acting insulin or oral diabetes medicines, along with proper diet and exercise. Follow your doctor’s advice and treatment plan to get the maximum benefit.

How should Biosulin R 40IU Injection be used?

Biosulin R 40IU Injection is injected under the skin (subcutaneously). Your doctor will show you the area of your skin where you should inject it. Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs or upper arms. Never inject Humalog into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of the body, making sure to move around within that area with each injection, for one or two weeks. You can then move to another area of your body and repeat the process. Use the same area for at least a week to avoid extreme blood sugar variations.

Is Biosulin R 40IU Injection safe to use in pregnancy?

Yes. Biosulin R 40IU Injection is safe to use in pregnancy if prescribed by a doctor. However, please inform your doctor if you are pregnant, planning pregnancy or breastfeeding before using Biosulin R 40IU Injection. You may require dose modifications and your doctor will advise you to monitor your blood sugar levels regularly. You must follow the instructions of your doctor to get maximum benefits.

Is Biosulin R 40IU Injection safe to use in type 2 diabetes?

Yes, insulin is safe to use in type 2 diabetes if used according to your doctor's advice. Keep monitoring your blood sugar levels regularly as advised. Your dosage may need to be adjusted as per your needs. Follow the lifestyle changes as advised by your doctor. Talk to your doctor about the side effects and ways to prevent and manage them.

What are the side effects of Biosulin R 40IU Injection? How to prevent them?

The side effects of Biosulin R 40IU Injection are injection site reactions such as redness, itching, pain and swelling. However, these are temporary and usually resolve on their own. Rarely, it can also cause lipodystrophy, which means abnormal changes in the fat tissues due to repeated insulin injections in the same area of the skin. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.

Can Biosulin R 40IU Injection cause hypoglycemia? How do I prevent it?

Yes, the most common side effect of Biosulin R 40IU Injection is hypoglycemia. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, do not skip meals and be consistent in the timing and amount of your meals. Take some snacks as per your requirement if you over exercise. Regular monitoring of the blood sugar level is important. Always carry some sugary candies, glucose/glucon-D or fruit juice with you. Take all the medicines prescribed by the doctor on time and consult your doctor if you notice any fluctuations in your blood sugar levels.

Is Biosulin R 40IU Injection given as an injection into a vein (intravenous)?

Yes, sometimes, in specific situations like diabetic ketoacidosis, severe hyperglycemia etc, Biosulin R 40IU Injection may be given as an injection into a vein (intravenous). However, in such cases, it is only given by a doctor, under continuous monitoring of blood sugar levels in a hospital setting.

When does the dosage of Biosulin R 40IU Injection need to be changed?

You should consult your doctor for dose adjustment if you experience weight gain or loss, increased stress, illness, changes in diet such as missed meals or if you are taking alcohol. Your dose may also change if you have recently changed your exercise regime or are taking any medicines. Also, you must be vigilant for certain side effects that you may experience while using Biosulin R 40IU Injection. Your doctor will tell you ways to prevent them. These side effects are usually temporary but if they are very severe, you may need dose modifications.

Does Biosulin R 40IU Injection need to be refrigerated?

Biosulin R 40IU Injection needs to be refrigerated before its first use. Unopened cartridges and unused pre-filled pens of Humalog must be stored in a refrigerator where the temperature is between 2°C to 8°C. Do not freeze and do not use Biosulin R 40IU Injection if it has been frozen. When the cartridge has been inserted into the injection pen, it should not be refrigerated and should be kept at room temperature, below 86°F (30°C) and must be used within 28 days or be discarded, even if they still contain Biosulin R 40IU Injection.

What is Biosulin R 40IU Injection? How is it made?

Biosulin R 40IU Injection is a man-made version of human insulin, produced by the process of biotechnology called recombinant DNA technology. It is sold as a sterile, aqueous, clear, and colorless solution that contains insulin aspart along with other constituents like glycerin, phenol, metacresol, zinc, sodium chloride etc.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 728-37.
Human Insulin. Bagsvaerd, Denmark: Novo Nordisk A/S; 2012. [Accessed 12 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:
Actrapid [Summary of Product Characteristics]. Bagsværd, Denmark; Novo Nordisk A/S, Novo Allé; 2007. [Accessed 13 October Sept. 2021] (online) Available from:
Humulin [Product monograph]. Toronto, Ontario; Eli Lilly Canada Inc.; 2011. [Accessed 13 October Sept. 2021] (online) Available from:
American Diabetes Association (ADA). Insulin administration (Position statement). Diabetes Care. 2004;27(Suppl 1): S106-S109. [Accessed 13 October 2021] (online) Available from:
Insulin [Package Insert]. Bengaluru, India: Biocon Biologics India Limited; 2019. [Accessed 03 Jul. 2023]. (online) Available from:

Marketer details

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Country of origin: India

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