Bonitar 400 Tablet
Prescription Required
Product introduction
Bonitar 400 Tablet is an anti-cancer medicine. It is used in the treatment of certain blood cancer known as chronic myeloid leukemia. This medicine helps to slow down the growth and multiplication of cancer cells, thereby reducing the progress of the disease.
Bonitar 400 Tablet should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how long. You may take it with or without food. Take it regularly and take it at a fixed time each day to help you remember. You should not stop taking the medicine suddenly and continue taking it for as long as the doctor has prescribed.
Common side effects of this medicine include respiratory tract infection, nasopharyngitis, low blood platelets, decreased white blood cell count, anemia, headache, breathlessness, cough, increased liver enzymes, diarrhea, vomiting, nausea, and abdominal pain. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. You should also inform the doctor immediately if it causes severe headaches, swelling in one leg, pain on breathing, or changes in vision or hearing.
Before taking Bonitar 400 Tablet, you should let your doctor know if you have any other preexisting medical conditions. You should also inform the doctor about all other medicines that you are taking. Pregnant and breastfeeding women should not take this medicine as it can cause harmful effects to the developing baby.
Bonitar 400 Tablet should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how long. You may take it with or without food. Take it regularly and take it at a fixed time each day to help you remember. You should not stop taking the medicine suddenly and continue taking it for as long as the doctor has prescribed.
Common side effects of this medicine include respiratory tract infection, nasopharyngitis, low blood platelets, decreased white blood cell count, anemia, headache, breathlessness, cough, increased liver enzymes, diarrhea, vomiting, nausea, and abdominal pain. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. You should also inform the doctor immediately if it causes severe headaches, swelling in one leg, pain on breathing, or changes in vision or hearing.
Before taking Bonitar 400 Tablet, you should let your doctor know if you have any other preexisting medical conditions. You should also inform the doctor about all other medicines that you are taking. Pregnant and breastfeeding women should not take this medicine as it can cause harmful effects to the developing baby.
Uses of Bonitar Tablet
Benefits of Bonitar Tablet
In Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also known as leukemia, is a cancer of the white blood cells or WBCs, that decreases the body's ability to fight infection. Bonitar 400 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Bonitar Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bonitar
- Abdominal pain
- Nausea
- Vomiting
- Diarrhea
- Headache
- Cough
- Low blood platelets
- Anemia (low number of red blood cells)
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Respiratory tract infection
- Decreased white blood cell count (neutrophils)
- Breathlessness
- Increased liver enzymes
How to use Bonitar Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bonitar 400 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Bonitar Tablet works
Bonitar 400 Tablet is a tyrosine kinase inhibitor that is used as an anti-cancer medication. It works by blocking the action of the abnormal protein that promotes the growth and spread of cancer. This helps to stop or slow the spread of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Bonitar 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Bonitar 400 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Bonitar 400 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Bonitar 400 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Bonitar 400 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Bonitar 400 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Bonitar 400 Tablet should be used with caution in patients with liver disease. Dose adjustment of Bonitar 400 Tablet may be needed. Please consult your doctor.
What if you forget to take Bonitar Tablet?
If you miss a dose of Bonitar 400 Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Bonitar 400 Tablet
₹272.3/Tablet
Bosutris 400 Tablet
Mylan Pharmaceuticals Pvt Ltd - A Viatris Company
₹293.7/tablet
8% costlier
Bosuvi 400mg Tablet
Glenmark Pharmaceuticals Ltd
₹297.67/tablet
9% costlier
Quick tips
- Bonitar 400 Tablet is used for the treatment of thyroid cancer.
- Take it with or without food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Fact Box
Chemical Class
4-aminoquinolines
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors
Interaction with drugs
Taking Bonitar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Domperidone with Bosutinib.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Tetrabenazine with Bosutinib.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ondansetron with Bosutinib.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Hydroxyzine with Bosutinib.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ondansetron with Bosutinib.
Patient concerns
FAQs
When should I call my doctor right away?
Get medical help right away if you have muscle cramping, muscle weakness, confusion, visual loss or disturbances, blindness, seizures, headaches, shortness of breath, swelling of your feet or changes in your heartbeat, high blood pressure, tiredness, fainting, coughing and breathing difficulties or tightness in the chest.
How will you know that Bonitar 400 Tablet is working?
Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.
What precautions should I take to reduce the chances of getting infected during treatment with Bonitar 400 Tablet?
Since Bonitar 400 Tablet lowers the number of white blood cells and platelets in your blood, it puts you at a risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters, and use a toothbrush with soft bristles to prevent bleeding from gums.
Can Bonitar 400 Tablet be used during pregnancy?
No, this medicine should not be used during pregnancy as it can harm your unborn baby. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 3 months after the last dose of Bonitar 400 Tablet.
Can Bonitar 400 Tablet affect my lungs? What should I do?
Yes, this medicine might cause potentially fatal problems in your lung. If you feel severe shortness of breath, confusion, dry cough, dizziness, or extreme tiredness, talk to your doctor right away.
Does Bonitar 400 Tablet cause hair loss?
Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.
Are there any precautions for tingling sensation and numbness in my arms and legs?
This medicine causes tingling, numbness, pain, or burning sensation in your arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dose or schedule.
I have noticed some changes in my skin after taking Bonitar 400 Tablet? What should I do?
Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen with (SPF more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water bath and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.
How to relieve constipation during the treatment?
To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.
I am experiencing nausea and extreme tiredness. Is this due to Bonitar 400 Tablet?
Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.
I am noticing a change in my taste. How shall I improve my taste?
You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You can also add extra flavor or seasonings to your food.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Bosutinib [FDA Label]. New York, NY: Pfizer Labs; 2017. [Accessed 18 Dec. 2020] (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
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