Bupine 0.3mg Injection is used to treat moderate to severe pain and opioid (morphine) dependence in patients who are also receiving medical, social, and psychological support. This medicine is not recommended for children below 16 years of age.

Bupine 0.3mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should continue receiving the medicine until the doctor tells you it is alright to stop.

The most common side effects of this medicine include weakness, drug withdrawal syndrome, anxiety, nervousness, dizziness, headache, sleepiness, diarrhea, nausea, vomiting, and abdominal pain. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have any respiratory disorders, problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Uses of Bupine Injection

Opioid (Morphine) dependence
Moderate to severe pain

Side effects of Bupine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bupine

Headache
Back pain
Drowsiness
Vomiting
Insomnia (difficulty in sleeping)
Drug withdrawal syndrome
Dizziness
Sleepiness
Abdominal pain
Weakness
Sweating
Constipation
Withdrawal syndrome
Infection
Vertigo
Inflammation of the nose
Chills
Flu-like symptoms
Nausea

How to use Bupine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bupine Injection works

Bupine 0.3mg Injection is a opioid partial agonist that provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Bupine 0.3mg Injection.

Pregnancy

CONSULT YOUR DOCTOR

Bupine 0.3mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Bupine 0.3mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Bupine 0.3mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Bupine 0.3mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Bupine 0.3mg Injection may be needed. Please consult your doctor.

Liver

CAUTION

Bupine 0.3mg Injection should be used with caution in patients with liver disease. Dose adjustment of Bupine 0.3mg Injection may be needed. Please consult your doctor.
Use of Bupine 0.3mg Injection is not recommended in patients with serious liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Bupine 0.3mg Injection

₹14.3/Injection

Buprene 0.6mg Injection

Tribhawan Injectables

₹18/injection

22% costlier

Quick tips

Bupine 0.3mg Injection is given as an injection by healthcare professionals only.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Bupine 0.3mg Injection can cause dizziness and sleepiness.
Avoid drinking alcohol or taking other medicines that can cause drowsiness.
Discontinue the medicine and inform your doctor if you experience difficulty breathing.
Do not stop taking Bupine 0.3mg Injection without talking to your doctor first as it may cause a worsening of symptoms.
Your doctor may get regular blood tests to check for liver function while taking this medicine.
Take it at the same time every day to help you remember to take it.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Use caution while driving or doing anything that requires concentration as Bupine 0.3mg Injection can cause dizziness and sleepiness.
Avoid drinking alcohol or taking other medicines that can cause drowsiness.
Discontinue the medicine and inform your doctor if you experience difficulty breathing.
Do not stop taking Bupine 0.3mg Injection without talking to your doctor first as it may cause a worsening of symptoms.
Your doctor may get regular blood tests to check for liver function while taking this medicine.

Fact Box

Chemical Class

Phenanthrenes Derivatives

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Opioids- Partial agonist

Patient concerns

Any pain tablet for cancer patent.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Lot of medicines for cancer patients some are simple pain killers like ibuprofen, voveron, paracetamolOther strong pain killers are from opioid groups of medicines like morphine, Fentanyl These u can not buy or use without supervision of a doctor

M having acne problm from last 10years they r vry big in size with pus.I had used many medicine but none of use.my skin is excess oily .m attaching u d pic of my acne it might help u to understand kindly suggest medicine

Dr. Souvik Sardar

Dermatology

Plz visit a dermatologist for prescription of oral medication this is moderate to severe

Why do i have stomach ache frequently and its my 2 nd month of pragnancy specily in the left lower abdomen my all usg n blood reports are normal

Dr. Megha Tuli

Obstetrics and Gynaecology

Hi PATIENT Lower abdomen pain and discomfort during pregnancy as the growing uterus puts pressure over the bladder. However if pain is moderate to severe then it could be due to an infection, please test for UTI to see for infection. Drink plenty of water and that should help. All the best.

User feedback

What are you using Bupine Injection for?

Opioid (Morph*

100%

*Opioid (Morphine) dependence

How much was the improvement?

Poor

100%

FAQs

What is Bupine 0.3mg Injection used for?

Bupine 0.3mg Injection is used to relieve severe pain when other pain medicines did not work well enough or cannot be tolerated. This medicine is not used for minor pain or pain that only sometimes occurs. It should not be used to treat pain that you only have once in a while or "as needed". It is also used to treat opioid use disorder.

How is Bupine 0.3mg Injection given?

This medicine should be injected into the skin and never into a vein. Injecting Bupine 0.3mg Injection into a vein or muscle could result in damage to the skin or underlying tissues, as well as a blood clot that could be fatal.

How fast Bupine 0.3mg Injection start to work after IV (intravenous) administration?

The analgesic (pain-relieving) effect after IV administration usually occurs within 10-30 minutes and the peak effects occur within 60 minutes.

How long the analgesic effect of Bupine 0.3mg Injection lasts?

The analgesic effect of Bupine 0.3mg Injection usually lasts for an average of six hours but the duration may vary between individuals.

After administration of Bupine 0.3mg Injection, I can feel a small lump under your skin. Is this normal?

Yes, you may see or feel a small lump under your skin where the medicine was injected. This could last for several weeks but the lump might eventually get smaller. Avoid rubbing or massaging the lump, or wearing tight clothing over the area. Consult your doctor if it worries you.

When should I see my doctor?

The person caring for you should seek medical help immediately if you have slow breathing with long pauses, blue-colored lips, or if you are hard to wake up.

Can I take alcohol with Bupine 0.3mg Injection?

This medicine may cause sleepiness or dizziness and affect your ability to drive or operate machinery. Avoid alcohol and consult your doctor in case of any doubts.

I feel dizzy when I get up from a sitting position or when I walk down the stairs. Is it due to Bupine 0.3mg Injection?

This medicine may cause a severe lowering of blood pressure, or a sudden drop in blood pressure when going from sitting to standing, especially if you are taking medications for high blood pressure. Talk to your doctor who might change your dosage.

Can Bupine 0.3mg Injection cause addiction?

This medicine may be addictive and cause psychological dependence and withdrawal symptoms, particularly when used for long periods of time.

Can I use Bupine 0.3mg Injection during pregnancy?

If you use Bupine 0.3mg Injection while you are pregnant, your baby could become dependent on the medicine. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

Can I use Bupine 0.3mg Injection while breastfeeding?

Bupine 0.3mg Injection can pass into breast milk and may cause drowsiness, and breathing problems in a breastfeeding baby. Ask your doctor in detail about all the risks.

Is Bupine 0.3mg Injection an opiate/ opiate blocker/ controlled substance/ pain killer/ addictive?

Bupine 0.3mg Injection belongs to a class of medications called opioid partial agonist-antagonists, which is used to relieve pain. It is a controlled substance and an addictive drug. Consult your doctor for alternate drug if you experience addiction

Does Bupine 0.3mg Injection block opiates?

Yes. Bupine 0.3mg Injection block opiates

Can Bupine 0.3mg Injection cause depression?

Bupine 0.3mg Injection is not known to cause depression. If you experience such side effects, please consult your doctor.

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Related lab tests

Opiates

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 546-47.
Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 510.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 165-67.
Drugs.com. Buprenorphine. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

Marketer details

Name: Paksons Pharmaceuticals Pvt Ltd

Address: 2/215 Maharaja Aggarsain Commercial Complex Sector 9 Rohini Delhi, Delhi, India.

Country of origin: India

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