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Busefan 60 Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Busefan 60 Injection is used in the treatment of some cancers of blood like chronic myeloid leukaemia. It is used in combination with other cancer medicines during hematopoietic progenitor cell transplantation (HPCT). It may also be used to treat some other types of cancer.

Busefan 60 Injection is given as an injection into veins by the healthcare provider. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include decreased blood cells (red cells, white cells, and platelets), nausea, vomiting, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.  Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Busefan Injection

In Blood cancer (Chronic myeloid leukaemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Busefan 60 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Busefan Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Busefan

  • Decreased blood cells (red cells, white cells, and platelets)
  • Nausea
  • Abdominal pain
  • Vomiting
  • Loss of appetite
  • Anxiety
  • Decreased magnesium level in blood
  • Decreased potassium level in blood
  • Diarrhea
  • Fever
  • Headache
  • Increased glucose level in blood
  • Insomnia (difficulty in sleeping)
  • Stomatitis (Inflammation of the mouth)

How to use Busefan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Busefan Injection works

Busefan 60 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Busefan 60 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Busefan 60 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Busefan 60 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Busefan 60 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Busefan 60 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Busefan 60 Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Busefan 60 Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Busefan Injection?

If you miss a dose of Busefan 60 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Busefan 60 Injection
₹8007/Injection
Emsulfan 60mg Injection
Emcure Pharmaceuticals Ltd
₹5500/injection
32% cheaper
Bufatas IV Injection
Intas Pharmaceuticals Ltd
₹8900/injection
10% costlier
Busulmax 60 Injection
GLS Pharma Ltd.
₹6500/injection
20% cheaper
Kabisulfan 60mg Injection
Fresenius Kabi India Pvt Ltd
₹5000/injection
38% cheaper
Bucelon 60mg Injection
Celon Laboratories Ltd
₹7200/injection
11% cheaper

Quick tips

  • Busefan 60 Injection is given as an injection into the vein by a healthcare provider.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor the levels of blood cells in your blood.
  • Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and sore throat.
     

Fact Box

Chemical Class
Organosulfonic Acid Esters Derivative {Alkylating Agent
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent

Patient concerns

arrow
She is suffering from chronic myeloid leukemia
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.
Mh mother have blood cancer .recently she got her first induction chemotherapy.in CBC test Immature myeloid cells 18 percent what are indicate.is it serious .is it shown presence of cancer in blood old tell me
Dr. Ila Jain Khandelwal
Pathology
Dear Mam Greetings from 1mg, The reports shows low hemoglobin and platelet count which can be due to chemotherapy.
arrow

FAQs

Does Busefan 60 Injection cause hair loss?

Yes, Busefan 60 Injection can cause hair loss.

Is Busefan 60 Injection a vesicant?

Yes. Busefan 60 Injection is a vesicant (irritant).

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1685-86.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 171-72.
  3. Busulfan. Greenville, North Carolina: DSM Pharmaceuticals, Inc.; 1999 [revised Jan. 2015]. [Accessed 26 Mar. 2019] (online) Avaialble from:External Link
  4. Drugs.com. Busulfan Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Busulfan. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:External Link

Marketer details

Name: Halsted Pharma Private Limited
Address: Ground floor, Plot No.25-HIG, Survey No.912P. 913P, 941P, 944P 945 to 962 and 964P Phase XV, KPHB Colony, Kukatpally. Medchal- Malkajgiri District, Telangana State, India.
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Busefan 60 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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10.0 ml in 1 vial
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