Cafirate Injection
Prescription Required
Product introduction
Cafirate Injection is a prescription medicine used in the treatment of apnea (a disorder in which breathing repeatedly stops and starts) of prematurity. It facilitates normal breathing and reduces interrupted breathing in premature newborns.
Cafirate Injection is given under the supervision of healthcare professionals. Remember, if you are breastfeeding while your infant is treated with this medicine, then do not drink coffee or take any other high caffeine product as this passes into breast milk.
Some common side effects of this medicine include mild delirium, insomnia, frequent urge to urinate, dehydration, tachycardia, and fever. Consult your doctor if these do not go away or persist for a longer duration. They may be able to suggest ways to prevent or reduce the side effects.
Cafirate Injection is given under the supervision of healthcare professionals. Remember, if you are breastfeeding while your infant is treated with this medicine, then do not drink coffee or take any other high caffeine product as this passes into breast milk.
Some common side effects of this medicine include mild delirium, insomnia, frequent urge to urinate, dehydration, tachycardia, and fever. Consult your doctor if these do not go away or persist for a longer duration. They may be able to suggest ways to prevent or reduce the side effects.
Uses of Cafirate Injection
- Apnea of prematurity
Benefits of Cafirate Injection
In Apnea of prematurity
In a premature baby, the part of the brain that controls breathing is not mature enough for nonstop breathing. This causes large bursts of breath followed by periods of shallow breathing or stopped breathing. This is called apnea or breathing trouble of prematurity. Cafirate Injection helps to stimulate those areas of the brain that control breathing and normalise it. It is given as an injection by a doctor or nurse.
Side effects of Cafirate Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cafirate
- Delirium (acute confusional state)
- Insomnia (difficulty in sleeping)
- Frequent urge to urinate
- Dehydration
- Fever
How to use Cafirate Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Cafirate Injection works
Cafirate Injection is a stimulant. It works by blocking the action of certain natural substances (adenosine and phosphodiesterase) leading to stimulation of the brain and respiratory system in premature newborns. This reduces the number of episodes of interrupted breathing and helps the newborns breathe on their own.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Cafirate Injection.
Pregnancy
CONSULT YOUR DOCTOR
Cafirate Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CAUTION
Cafirate Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
UNSAFE
Cafirate Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Cafirate Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Cafirate Injection in patients with liver disease. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Cafirate Injection
₹335/Injection
Capnea Injection
Cipla Ltd
₹561.12/injection
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Capnea Injection
Cipla Ltd
₹280.55/injection
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Cafneon 20mg/ml Injection
Neon Laboratories Ltd
₹280/injection
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Quick tips
- Cafirate Injection helps in the treatment of interrupted breathing in premature babies.
- It is given as an injection (drip) by your doctor or nurse.
- If you are breast-feeding while your infant is treated with Cafirate Injection, do not drink coffee or take any other high caffeine product as caffeine passes into breast milk.
Fact Box
Chemical Class
Xanthine Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Adenosine receptor (A1 & A2) antagonist
Interaction with drugs
Taking Cafirate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Caffeine may reduce the efficacy of Adenosine.
It is recommended to avoid Caffeine for at least 24 hours before taking Adenosine. Please consult your doctor accordingly.
Axitinib may raise blood levels of Caffeine.
If concurrent use is essential, watch out for symptoms such as acute confusional state, difficulty in sleeping, frequent urge to urina
Caffeine may reduce the efficacy of Phenobarbitone.
It is recommended to avoid Caffeine after taking Phenobarbitone, especially at bedtime.
Caffeine may reduce blood levels of Leflunomide.
Your doctor may monitor the effects of Leflunomide when taken concurrently with Caffeine.
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- O’Brien CP. Drug Addiction. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 663.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 179-83.
- Tulane University: School of Medicine. Caffeine. [Accessed 29 Jan. 2019] (online) Available from:
- Drugs.com. Caffeine Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Caffeine. [Updated 2019 Jun 30]. [Accessed 20 Feb. 2020] (online) Available from:
Marketer details
Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India
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