Cafirate Oral Solution is a prescription medicine used in the treatment of apnea (a disorder in which breathing repeatedly stops and starts) of prematurity. It facilitates normal breathing and reduces interrupted breathing in premature newborns.

Cafirate Oral Solution is given under the supervision of healthcare professionals. It is given by mouth or via a gastric feeding tube only. Remember, if you are breastfeeding while your infant is treated with this medicine, then do not drink coffee or take any other high caffeine product as this passes into breast milk.

Some common side effects of using this medicine are restlessness, insomnia, headaches, dizziness, increased heart rate. Consult your doctor if these persist for a longer duration or get worse. They may be able to suggest ways to prevent or reduce these side effecrts.

Uses of Cafirate Oral Solution

Apnea of prematurity

Side effects of Cafirate Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cafirate

Restlessness
Headache
Dizziness
Increased heart rate
Insomnia (difficulty in sleeping)

How to use Cafirate Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Cafirate Oral Solution may be taken with or without food, but it is better to take it at a fixed time.

How Cafirate Oral Solution works

Cafirate Oral Solution is a stimulant. It works by blocking the action of certain natural substances (adenosine and phosphodiesterase) leading to stimulation of the brain and respiratory system in premature newborns. This reduces the number of episodes of interrupted breathing and helps the newborns breathe on their own.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Cafirate Oral Solution.

Pregnancy

CONSULT YOUR DOCTOR

Cafirate Oral Solution may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Cafirate Oral Solution should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

UNSAFE

Cafirate Oral Solution may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Cafirate Oral Solution in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Cafirate Oral Solution in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Cafirate Oral Solution

₹630/Oral Solution

Capnea Solution

Cipla Ltd

₹275.15/oral solution

58% cheaper

Capnea Solution

Cipla Ltd

₹440/oral solution

32% cheaper

Cafneon OS 20mg Oral Solution

Neon Laboratories Ltd

₹275/oral solution

58% cheaper

Quick tips

Cafirate Oral Solution helps in the treatment of interrupted breathing in premature babies.
If you are breast-feeding while your infant is treated with Cafirate Oral Solution, do not drink coffee or take any other high caffeine product as caffeine passes into breast milk.

Fact Box

Chemical Class

Xanthine Derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Adenosine receptor (A1 & A2) antagonist

Interaction with drugs

Taking Cafirate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Adenosine (Oral Route) Moderate

Caffeine may reduce the efficacy of Adenosine. It is recommended to avoid Caffeine for at least 24 hours before taking Adenosine. Please consult your doctor accordingly.

Axitinib (Oral Route) Moderate

Axitinib may raise blood levels of Caffeine. If concurrent use is essential, watch out for symptoms such as acute confusional state, difficulty in sleeping, frequent urge to urina... More

Phenobarbitone (Oral Route) Moderate

Caffeine may reduce the efficacy of Phenobarbitone. It is recommended to avoid Caffeine after taking Phenobarbitone, especially at bedtime.

Leflunomide (Oral Route) Moderate

Caffeine may reduce blood levels of Leflunomide. Your doctor may monitor the effects of Leflunomide when taken concurrently with Caffeine.

Amoxapine (Oral Route) Moderate

Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More

View all drug interactions

Patient concerns

Sleep apnea ? Please help

Dr. Vijay Verma

ENT

get sleep study and revert

What is the best medicine for sleep apnea How to control sleep apnea

Dr. Vijay Verma

ENT

Reduction of weight is the only treatment along with that do sleep study to see for severity

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 179-83.
Tulane University: School of Medicine. Caffeine. [Accessed 29 Jan. 2019] (online) Available from:
Drugs.com. Caffeine Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Caffeine. [Updated 2019 Jun 30]. [Accessed 20 Feb. 2020] (online) Available from:
Caffeine. Harold Hill: Macarthys Laboratories Limited; 2011 [revised 8 Aug. 2018]. (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 20 Mar. 2019] (online) Available from:

Marketer details

Name: Sun Pharmaceutical Industries Ltd

Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.