Cardifine 12.5mg Tablet is a medicine used to treat high blood pressure, heart-related chest pain (angina), and heart failure. It works by relaxing the blood vessels, so blood can flow more easily to the heart. Lowering blood pressure also helps prevent future heart attacks and stroke.

Cardifine 12.5mg Tablet should be taken with food. You should take it in the dose and duration as advised by the doctor. It is important to take it even if you feel well or if your blood pressure is controlled. Do not stop this medicine without talking to the doctor as your condition could get worse.

Making some changes in your lifestyle will help in improving your condition. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor.

This medicine is tolerated well by most patients but it may have a few side effects. These include dizziness, headache, breathlessness, and tiredness. Let your doctor know if these side effects bother you or do not go away.

Before taking this medicine, let your doctor know if you have any heart or kidney diseases. Pregnant or breastfeeding mothers should also consult their doctor before taking this medicine.

Uses of Cardifine Tablet

Benefits of Cardifine Tablet

In Treatment of Hypertension (high blood pressure)

Cardifine 12.5mg Tablet works by blocking the effects of some chemicals on your heart and blood vessels. It slows down your heart rate and helps the heart to beat with less force. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

In Treatment of Angina (heart-related chest pain)

Cardifine 12.5mg Tablet relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily by reducing the frequency of angina attacks. You should take it regularly and as long as it is prescribed for it to work effectively.

In Treatment of Heart failure

Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other parts of your body. Cardifine 12.5mg Tablet makes it easier for your heart to pump blood around your body and is, therefore, effective treatment for heart failure.

This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

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Side effects of Cardifine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cardifine

Decreased blood pressure
Headache
Fatigue
Dizziness
Breathlessness

How to use Cardifine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cardifine 12.5mg Tablet is to be taken with food.

How Cardifine Tablet works

Cardifine 12.5mg Tablet is an alpha and beta blocker. It works by slowing down the heart rate and relaxing blood vessels which makes the heart more efficient at pumping blood around the body.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Cardifine 12.5mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Cardifine 12.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Cardifine 12.5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Cardifine 12.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Cardifine 12.5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Cardifine 12.5mg Tablet is recommended.
However, inform your doctor if you have any underlying kidney disease. Regular monitoring of blood pressure is recommended for dose adjustment.

Liver

CAUTION

Cardifine 12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cardifine 12.5mg Tablet may be needed. Please consult your doctor.
Use of Cardifine 12.5mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Cardifine Tablet?

If you miss a dose of Cardifine 12.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Cardifine 12.5mg Tablet

₹10.9/Tablet

Cardivas 12.5 Tablet

Sun Pharmaceutical Industries Ltd

₹14.4/tablet

32% costlier

Carloc 12.5 Tablet

Cipla Ltd

₹11.07/tablet

2% costlier

Carvistar 12.5 Tablet

Lupin Ltd

₹8.07/tablet

26% cheaper

Carvil 12.5 Tablet

Zydus Cadila

₹13.5/tablet

24% costlier

Carca 12.5 Tablet

Intas Pharmaceuticals Ltd

₹12.6/tablet

16% costlier

View all substitutes

Quick tips

It should be taken with food.
Check your blood pressure 1 week after starting Cardifine 12.5mg Tablet, and inform your doctor if it has not improved.
Cardifine 12.5mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
It is best to avoid drinking alcohol while taking Cardifine 12.5mg Tablet as it may make the side effects worse.
Do not stop taking Cardifine 12.5mg Tablet suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

Fact Box

Chemical Class

Carbazole & propanol derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Alpha & beta blocker

Patient concerns

What is heart attack? When heart attack coming?

Dr. Nabajit Talukdar

Cardiology

Related to chest pain angina commonly

Heart pain blood pressure high blood sugar high

Dr. Saurabh Arora

Cardiology

Consult physician near u for proper examination and blood work up

Diabetes with heart paining and high BLood pressure

Dr. Sanjay Bhatt

Physician

It is not good control. A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

What happens when you stop taking Cardifine 12.5mg Tablet?

Cardifine 12.5mg Tablet needs to be taken regularly as directed by your doctor. Suddenly stopping it may cause chest pain or heart attack. Your doctor may slowly lower your dose over a period of time before stopping it completely if required.

Does Cardifine 12.5mg Tablet make you tired?

Yes, Cardifine 12.5mg Tablet may make you tired as well as dizzy. These may occur initially when you start the treatment or when the dose is increased. If you experience these symptoms you should not drive or operate machinery.

Can Cardifine 12.5mg Tablet cause weight gain?

Yes, weight gain is a common side effect of Cardifine 12.5mg Tablet, but it does not occur in everyone. If you are taking Cardifine 12.5mg Tablet for heart failure, tell your doctor if you gain weight or have trouble breathing, as this may be a sign of fluid retention.

Can Cardifine 12.5mg Tablet cause kidney failure?

Use of Cardifine 12.5mg Tablet in patients with heart failure can rarely lead to deterioration of kidney function. However, Cardifine 12.5mg Tablet may cause risk of kidney failure in patients with low blood pressure (systolic blood pressure less than 100 mm Hg), patients with hardening of the arteries and/or having heart disease, or already have impaired kidney function. Such patients should be closely monitored during treatment with Cardifine 12.5mg Tablet. Although, kidney functions return to baseline when Cardifine 12.5mg Tablet is stopped.

Can a diabetic patient take Cardifine 12.5mg Tablet?

Yes, a diabetic patient can take Cardifine 12.5mg Tablet, provided that there is a regular check on blood glucose levels. It has been noted that in well-controlled diabetes mellitus with mild to moderate hypertension, Cardifine 12.5mg Tablet did not have any effect on blood glucose levels. However, it is important to know that, using Cardifine 12.5mg Tablet class of medicines (beta-blockers) may hide the symptoms of hypoglycemia (decrease in glucose levels), especially an increase in heartbeat or palpitations. In addition to that, Cardifine 12.5mg Tablet may cause worsening of hyperglycemia (increase in blood glucose levels) in patients with heart failure and diabetes. Hence, it is recommended that blood glucose should be monitored while initiating, adjusting, or discontinuing the dose of Cardifine 12.5mg Tablet. Inform the doctor if there is any change in blood glucose levels during Cardifine 12.5mg Tablet therapy.

Can I take Cardifine 12.5mg Tablet empty stomach?

It is recommended that you take Cardifine 12.5mg Tablet with food, as food decreases the rate at which the medicine gets absorbed by the body. This will help to reduce the chances of orthostatic hypotension (low blood pressure which may cause dizziness or fainting when you stand up).

What are the serious side effects of Cardifine 12.5mg Tablet?

Cardifine 12.5mg Tablet may cause serious side effects such as fainting, shortness of breath, weight gain, swelling of the arms, hands, feet, ankles, or lower legs. Some may also experience chest pain, slow or irregular heartbeat, rash, hives, itching, and difficulty in breathing and swallowing. If you experience any of these symptoms call your doctor immediately.

What if I take more than the recommended dose of Cardifine 12.5mg Tablet?

If you take more than the recommended dose of Cardifine 12.5mg Tablet you may experience slow heartbeat, dizziness, fainting, difficulty breathing, vomiting, and loss of consciousness or seizures. Contact your doctor and seek immediate medical help in a nearby hospital.

Who should not take Cardifine 12.5mg Tablet?

Cardifine 12.5mg Tablet should be avoided if the patient has severe heart failure and is hospitalized in the intensive care unit or require certain intravenous medications that help support circulation (inotropic medications). In addition to that, Cardifine 12.5mg Tablet should be avoided in patients who are prone to asthma or other breathing problems, have a slow heartbeat or irregular heartbeat, have liver problems, and are allergic to Cardifine 12.5mg Tablet.

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References

Maron BA, Rocco TP. Pharmacotherapy of Congestive Heart Failure. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 801.
Robertson D, Biaggioni I. Adrenoreceptor Antagonist Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 159-177.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 214-15.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Carvedilol. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Carvedilol. [Accessed 15 Mar. 2019] (online) Available from:
Singh S, Preuss CV. Carvedilol. [Updated 2023 Mar 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 12 Jun, 2023] (online) Available from:
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