Carpine 0.5% Injection
Prescription Required
Product introduction
Carpine 0.5% Injection is used in the treatment of dry mouth after radiotherapy of head and neck cancer. It works by reducing abnormal dryness of the mouth which makes speaking and swallowing easier.
Carpine 0.5% Injection must be administered by a healthcare professional in the hospital or in a clinical setting. You should not self administer this medicine at home.
The most common side effects of this medicine are headache, sweating, frequent urge to urinate, and flu syndrome. If you experience such symptoms that persist or worsen, or any other symptoms which you think may be due to this medicine, inform your doctor.
It is not advised to drive after using this injection as it may decrease your alertness and make you feel dizzy.
Uses of Carpine Injection
Benefits of Carpine Injection
In Dry mouth after radiotherapy of head and neck cancer
Radiation therapy to the head, face, or neck may also cause dry mouth. It can take 6 months or longer after radiation therapy ends for the salivary glands to start producing saliva again. Carpine 0.5% Injection helps to increase the secretions of body fluids, particularly saliva and this helps to improve dry mouth due to radiation therapy. It is given as an injection by a doctor or nurse and should not be self-administered.
Side effects of Carpine Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Carpine
- Headache
- Sweating
- Frequent urge to urinate
- Flu-like symptoms
How to use Carpine Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Carpine Injection works
Carpine 0.5% Injection is a cholinergic agonist. It works by reducing abnormal dryness of the mouth that may occur in certain immune disorders or due to radiation therapy for head and neck cancer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Carpine 0.5% Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Carpine 0.5% Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Carpine 0.5% Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Carpine 0.5% Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Carpine 0.5% Injection should be used with caution in patients with kidney disease. Dose adjustment of Carpine 0.5% Injection may be needed. Please consult your doctor.
Liver
CAUTION
Carpine 0.5% Injection should be used with caution in patients with liver disease. Dose adjustment of Carpine 0.5% Injection may be needed. Please consult your doctor.
Use of Carpine 0.5% Injection is not recommended in patients with severe liver disease.
Use of Carpine 0.5% Injection is not recommended in patients with severe liver disease.
What if you forget to take Carpine Injection?
If you miss a dose of Carpine 0.5% Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Carpine 0.5% Injection
₹15.7/Injection
Pilomin 0.5% Injection
Entod Pharmaceuticals Ltd
₹19.71/injection
22% costlier
Quick tips
- Inform your doctor if you have eye inflammation, suffer from asthma, liver, kidney or heart diseases, Parkinson’s disease, stomach ulcer, have problems in passing urine, high blood pressure, narrow angle glaucoma (increased eyeball pressure due to obstruction to the outflow of fluid).
- Drink sufficient water to reduce dehydration due to excessive sweating caused by pilocarpine.
- The back layer of your eye (fundus) may be examined before starting pilocarpine therapy.
- You may be regularly monitored for visual fields and intra-ocular pressure on long term therapy with pilocarpine for glaucoma.
- Do not drive or operate machinery as pilocarpine causes dizziness and blurring of vision especially in the night.
- Tell your doctor if you are pregnant, planning to become pregnant or are breast-feeding.
Fact Box
Chemical Class
Alkaloids Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Cholinomimetic Alkaloids- Pilocarpine
Interaction with drugs
Taking Carpine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Rivastigmine may increase the metabolism of Pilocarpine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Pilocarpine may increase the effect of Donepezil.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Pilocarpine may increase the effect of Galantamine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Rivastigmine may increase the metabolism of Pilocarpine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Patient concerns
User feedback
What are you using Carpine Injection for?
Others
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FAQs
Does Carpine 0.5% Injection increase or decrease heart rate?
Carpine 0.5% Injection can decrease the heart rate. However, it does not increase the heart rate.
Does Carpine 0.5% Injection cause weight gain/increase blood pressure?
Carpine 0.5% Injection increases blood pressure. However, no clinically relevant effect on weight has been reported with the use of Carpine 0.5% Injection.
Does Carpine 0.5% Injection help dry eyes?
Yes, Carpine 0.5% Injection helps dry eyes by increasing the production of tears.
Does Carpine 0.5% Injection work?
Carpine 0.5% Injection acts by increasing the activity of chemical acetylcholine, thereby, increasing the secretion from various glands including salivary glands and tear glands. Due to its cholinergic effect, it also constricts the pupil of the eye and improves the outflow of aqueous humor (fluid in within the eye) contributing to reduction in eyeball pressure.
Does Carpine 0.5% Injection cause blurred vision/hair loss?
Yes, Carpine 0.5% Injection causes blurred vision. But, it does not cause hair loss.
How does Carpine 0.5% Injection affect heart rate?
Carpine 0.5% Injection decreases heart rate by increasing the effect of a chemical called as acetylcholine.
How does Carpine 0.5% Injection lower intraocular pressure?
Carpine 0.5% Injection lowers intraocular pressure by constricting the ciliary muscle of the eyes, therefore increasing the outflow of fluid (aqueous humor) from posterior part of the eye.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1120-21.
- PubChem. Pilocarpine. [Accessed 04 Apr. 2019] (online) Available from:
- Pilocarpine hydrochloride. Luxembourg: Merus Labs Luxco S.a.R.L.; 2001 [revised 01 Apr. 2016]. [Accessed 28 Jan. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
- Pilocarpine Hydrochloride Ophthalmic Solution [Prescribing Information]. Fort Worth, TX: Alcon laboratories, Inc.; 2011. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
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