Product introduction
Cholibet 10mg Tablet is used in alone or in combination therapy to treat primary biliary cirrhosis. It helps improve the liver function by inhibiting the production of bile acid and increasing the removal of bile acid from the liver. This reduces the bile acid in the liver and hence prevents its toxic effects.
Cholibet 10mg Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete the full course of the medicine as prescribed by your doctor. Do not stop taking it until you have finished.
The most common side effects of this medicine include itching, fatigue, rash, throat pain, dizziness, constipation, joint pain, eczema, and thyroid disorders. If you experience any of these side effects that does not resolve on its own or get worse, you should let your doctor.
Before taking the medicine, tell your doctor if you have any other medical conditions. You should also let your doctor know about all the other medicines you are taking (if any), as they may affect or be affected by this medicine. Consult your doctor before using this medicine if you are pregnant or breastfeeding.
Uses of Cholibet Tablet
- Treatment of Primary biliary cirrhosis
Benefits of Cholibet Tablet
Side effects of Cholibet Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cholibet
- Throat pain
- Itching
- Fatigue
- Abdominal discomfort
- Rash
- Joint pain
- Oropharyngeal pain
- Dizziness
- Constipation
- Peripheral edema
- Palpitations
- Fever
- Thyroid disorders
- Eczema
How to use Cholibet Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cholibet 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Cholibet Tablet works
Cholibet 10mg Tablet stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Cholibet 10mg Tablet inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.
Safety advice
AlcoholCONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cholibet 10mg Tablet. Please consult your doctor.
PregnancyCONSULT YOUR DOCTOR
Information regarding the use of Cholibet 10mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feedingCONSULT YOUR DOCTOR
Information regarding the use of Cholibet 10mg Tablet during breastfeeding is not available. Please consult your doctor.
DrivingCONSULT YOUR DOCTOR
It is not known whether Cholibet 10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Cholibet 10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Cholibet 10mg Tablet may not be needed in these patients. Please consult your doctor.
Cholibet 10mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Cholibet 10mg Tablet may be needed. Please consult your doctor.
What if you forget to take Cholibet Tablet?
If you miss a dose of Cholibet 10mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Cholibet 10mg Tablet
₹36.4/Tablet
Quick tips
- Cholibet 10mg Tablet is used for the treatment of primary biliary cirrhosis.
- Your liver function will be monitored closely while on treatment with Cholibet 10mg Tablet.
- Eat a well-balanced diet and indulge in some sort of physical activity daily in order to reduce fatigue and improve well-being.
- Itching is one of the common side effects of Cholibet 10mg Tablet. Follow these tips to manage itching:
a) Keeping cool will also tend to reduce itch, compared to being warm. Cool showers or cold flannels may be helpful.
b)Dry skin can make the itch worse, so using liberal amounts of moisturizer is useful if you have dry skin.
c) Do not scratch as scratching will generally make it worse. If scratching is irresistible it may help to rub the itchy area with an ice cube.
Fact Box
Chemical Class
Dihydroxy bile acids, alcohols and derivatives
Therapeutic Class
GASTRO INTESTINAL
Action Class
Hepatoprotectives
Interaction with drugs
Taking Cholibet with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Cholestyramine may reduce the efficacy of Obeticholic acid.
To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Cholestyramine.
Obeticholic acid may raise blood levels of Theophylline.
watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may ... More
Obeticholic acid may raise blood levels of Tizanidine.
watch out for symptoms of Tizanidine side effects such as breathlessness, fatigue, drowsiness, sedation or faintness or vomi... More
Obeticholic acid may raise blood levels of Warfarin.
Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly.
Colesevelam may reduce the efficacy of Obeticholic acid.
To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Colesevelam.
Patient concerns
Suffering from chronic liver parenchymal disease since last three months is it curable and what food habit will follow?
Dr. Sfurti Mann
Internal Medicine
Liver cirrhosis can not be cured. Cause of liver cirrhosis needs to be worked up as well as upper GI endoscopy to look for varies. Avoid alcohol & pain killers .
attached is the report these are the medicines I've been taking: 1.udiplus 2.lecithin capsules - essential l 3.liv 52 ds since the last 10 days, the ggtp level is not going down from this level (84). what could be the reason?? is there any way or medicine to get it low?
Dr. Sfurti Mann
Internal Medicine
Alcohol can be a reasonOr obstruction in the biliary pathway
Suffering from cirrhosis. portal hypertension. what is the cure.
Dr. Vishant Rana
Homeopathy
only constitutional treatment can help. cirrhosis is a very serious condition
Suffering liver of the cirrhosis
Please consult a Hepatologist for this You will require a physical examination by a doctor
Liver cirrhosis & fatty liver gastric problem
Dr. Ankur Kumar Tanwar
Ayurveda
Ok please review with all reports and if possible meet me personally in clinic
Having primary stage of asthma
Dr. Saurabh Arora
Cardiology
Please consult chest physician
What are symptoms of cirrhosis
Hello Ajya Common sypmtoms associated with cirrhosis are Loss of appetite, yellowish discoluration of skin and eyes, fatigue , skin itching, easy skin buises, abdominal distention
My sgpt and sgot levels are 84 and 73 what medicines and how long to be taken
Dr. Sfurti Mann
Internal Medicine
Cause of this should be evaluated. Get ultrasound abdomen for liver and biliary system , hba1c, lipid profile
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
Obeticholic acid [FDA Label]. New York, NY: Intercept Pharmaceuticals, Inc.; 2016. [Accessed 30 Jun. 2020]. (online) Available from:
Obeticholic Acid [Package Infirmation Sheet]. Haridwar, Uttarakhand: Akums Drugs & Pharmaceuticals Ltd.; 2020. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Future Pharma Pvt Ltd
Address: 119/471 DARSHAN PURWA KANPUR UP 208012 IN , - , .
Country of origin: India
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