Clonil 25 Tablet is a tricyclic antidepressant. It is used in adults to treat obsessive-compulsive disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is unresponsive to other medicines.
Clonil 25 Tablet works by increasing the level of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel sleepy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose will need to be gradually decreased when the doctor decides to stop it.
The most common side effects of this medicine include increased heart rate, blurred vision, and constipation. Initially, this medicine may also cause a sudden drop in the blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not addictive, but you can get extra side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency.
Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
Benefits of Clonil Tablet
In Depression
Clonil 25 Tablet is thought to work by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, help you sleep better, and increase your energy level. It is used to treat depression that is unresponsive to other medicines. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.
In Obsessive-compulsive disorder
Obsessive-compulsive disorder (OCD) is a disorder that affects mental health. People may develop a cycle of obsessions and compulsions, irrespective of age. Obsessions are unwanted, repeated thoughts, images, or urges that trigger excessively distressing feelings. Clonil 25 Tablet helps relieve symptoms of obsessive-compulsive disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than other medicines and is normally taken once a day. Keep taking the medicine until your doctor advises you to stop.
In Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
Narcolepsy is a sleep disorder that causes excessive daytime drowsiness. The affected person may experience excessive sleepiness, sleep paralysis, hallucinations, and in some cases episodes of cataplexy (partial or total loss of muscle control). Clonil 25 Tablet stimulates the brain and makes you fully awake. It also relieves these abnormal symptoms and regulates the sleep cycle. This restores normal sleeping habits and improves your quality of life. You will feel more energetic and will be able to perform better in your daily activities.
Side effects of Clonil Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clonil
Constipation
Nausea
Altered libido
Dizziness
Fatigue
Increased appetite
Sweating
Drowsiness
Urinary incontinence
Tremors
Weight gain
Aggravation of depression
Agitation
Anxiety
Blurred vision
Delirium (acute confusional state)
ECG changes
Headache
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Ringing in ear
Sleep disorder
Confusion
Hallucination
Mania
Micturition disorders
Altered blood sugar level
How to use Clonil Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonil 25 Tablet is to be taken with food.
How Clonil Tablet works
Clonil 25 Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Clonil 25 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Clonil 25 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Clonil 25 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Clonil 25 Tablet may cause side effects which could affect your ability to drive. If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Clonil 25 Tablet, do not drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Clonil 25 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Clonil 25 Tablet should be used with caution in patients with liver disease. Dose adjustment of Clonil 25 Tablet may be needed. Please consult your doctor. Regular monitoring of liver function tests is advisable when you are taking this medicine.
What if you forget to take Clonil Tablet?
If you miss a dose of Clonil 25 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
It may take 4 to 6 weeks for Clonil 25 Tablet to start working. Keep taking it as prescribed.
It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Clonil 25 Tablet as it may cause excessive sleepiness.
Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Fact Box
Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic antidepressants
Patient concerns
I suffer from panic disorders.last 14 year and take zapiz 0.5 Clonil 25 me. But not recover. Advise me.
Dr. Jyoti Kapoor Madan
Psychiatry
Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. Treatment for Recurrent Depressive Disorder , psychotic disorders, Bipolar Affective Disorder and OCD usually lasts for much longer.To monitor any potential side effects and to take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions. Response to medicines depends on- 1. Diagnosis 2. Adequate dose of medicines 3. Adequate duration of treatment 4. Regular Medicines 5. Individual factors like patient's metabolism, other medical conditions etc.
Suffering from insomnia Regularly taking stresnil 0.5 and clonil 0.5 Otherwise falling asleep.
Dr. Jyoti Kapoor Madan
Psychiatry
Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below - http://drjyotikapoor.com/2015/01/26/sleep-disorders/
I have generalised anxiety disorder as per with medicines it would take 2years to recover Medicines clonil Sr 75,Selzic OD 300,Pari CR 25
Dr. Venkatraju Kalidindi
Psychiatry
Dear 1mg-user, we understand your feelings you need counselling for anxiety, counselling will help you to come out of your problem and many patients are cured and enjoying better life after counselling, but we need to talk to you to take full details in-person or Audio(Phone)/Video before we suggest something to cure your problem. Pay Rs 99 and call me on my phone www.dontfeel.com
Obsessive-Compulsive Disorder (OCD) is a common, chronic and long-lasting disorder in which a person has uncontrollable, reoccurring thoughts (obsessions) and behaviors (compulsions) that he or she feels the urge to repeat over and over. It's a neurochemical disturbance in brain and worsens due to stressful environment. OCD is typically treated with medication, psychotherapy or a combination of the two.
What were the side-effects while using Clonil 25 Tablet?
Sleepiness
23%
Constipation
23%
Difficulty in*
18%
Dryness in mo*
14%
No Side Effec*
9%
*Difficulty in urination, Dryness in mouth, No Side Effect
How do you take Clonil Tablet?
With food
69%
With or witho*
23%
Empty stomach
8%
*With or without food
Please rate Clonil 25 Tablet on price
Expensive
46%
Average
31%
Not Expensive
23%
FAQs
Can Clonil 25 Tablet cause impotence?
Yes, Clonil 25 Tablet can cause impotence. Both men and women may experience decreased sexual desire and inability to have an organsm. In males, difficulty in maintaining erection (impotence) or painful ejaculation may be observed. You should consult your doctor immediately if you face any such problems while taking Clonil 25 Tablet.
Is Clonil 25 Tablet safe?
Yes, Clonil 25 Tablet is safe to use if taken in the dose and duration prescribed by the doctor. Clonil 25 Tablet is a medicine that treats Obsessive-Compulsive Disorder (OCD), stabilises mood and behavior. It restores the chemical imbalance in the brain and creates a feeling of well being.
What are the side effects of Clonil 25 Tablet?
Clonil 25 Tablet may cause side effects like difficulty or inability to pass urine, altered libido, constipation, dryness in mouth, ejaculation disorder, indigestion and sleepiness. Please consult your doctor if these side effects worry you. The doctor may suggest ways to treat or prevent them.
What happens if I take an overdose of Clonil 25 Tablet?
If you have taken an overdose of Clonil 25 Tablet, you may experience symptoms such as drowsiness, restlessness, agitation and delirium (disturbed state of mind with restlessness and mental confusion). You may also experience severe sweating, fast heartbeat, feeling of faint, seizures (fits), and you may even go into a state of coma. Immediately consult your doctor and seek medical help if you think you have taken too much of this medicine.
If I am feeling better, can I stop taking Clonil 25 Tablet?
No, do not stop taking Clonil 25 Tablet suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking Clonil 25 Tablet for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Stahl SM, editor. Clomipramine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 129-35.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 298-300.
Clomipramine hydrochloride. Whitby, Ontario, Canada: Patheon Inc.; [revised Jun. 2014]. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from: