Closolin 250mg/250mg Capsule is a combination medicine that is used to treat various types of bacterial infections. It fights against the microorganisms to prevent their growth and further spread of the infection.

Closolin 250mg/250mg Capsule is a prescription medicine. It is advised to take it as per the prescription. It can be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.

Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

Uses of Closolin Capsule

Treatment of Bacterial infections

Benefits of Closolin Capsule

In Treatment of Bacterial infections

Closolin 250mg/250mg Capsule is a combination of two antibiotics, Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Closolin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Closolin

Allergic reaction
Rash
Stomach pain
Nausea
Diarrhea

How to use Closolin Capsule

Take this medicine in the dose and duration as advised by your doctor. Closolin 250mg/250mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Closolin Capsule works

Closolin 250mg/250mg Capsule is a combination of two antibiotics: Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively.

Safety advice

Alcohol

SAFE

Consuming alcohol with Closolin 250mg/250mg Capsule does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

Closolin 250mg/250mg Capsule is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Closolin 250mg/250mg Capsule is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Closolin 250mg/250mg Capsule does not usually affect your ability to drive.

Kidney

CAUTION

Closolin 250mg/250mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Closolin 250mg/250mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advised while taking this medicine.

Liver

CAUTION

Closolin 250mg/250mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Closolin 250mg/250mg Capsule may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised while taking this medicine.

What if you forget to take Closolin Capsule?

If you miss a dose of Closolin 250mg/250mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Closolin 250mg/250mg Capsule

₹2.23/Capsule

Ampoxin 500 Capsule

Torrent Pharmaceuticals Ltd

₹6.93/capsule

211% costlier

Megapen Capsule

Aristo Pharmaceuticals Pvt Ltd

₹6.6/capsule

196% costlier

Megaclox Capsule

Cipla Ltd

₹9.4/capsule

322% costlier

Ampikem C 250mg/250mg Capsule

Alkem Laboratories Ltd

₹11.1/capsule

398% costlier

Megabact 250 mg/250 mg Capsule

Cipla Ltd

₹6.4/capsule

187% costlier

View all substitutes

Quick tips

You have been prescribed this combination medicine to treat bacterial infections.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Closolin 250mg/250mg Capsule may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Take it with food and plenty of fluids to avoid an upset stomach.
Stop taking Closolin 250mg/250mg Capsule and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

I have a history of recurring yeast and bacterial vaginosis infections.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days

FAQs

How long does Closolin 250mg/250mg Capsule takes to work?

Usually, Closolin 250mg/250mg Capsule starts working soon after using it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Can I stop taking Closolin 250mg/250mg Capsule when I feel better?

No, do not stop taking Closolin 250mg/250mg Capsule and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

What is Closolin 250mg/250mg Capsule used for?

Closolin 250mg/250mg Capsule is used to treat patients with bacterial infections. It is a semi-synthetic derivative of the drug penicillin. It is used to treat urinary tract and respiratory tract infections, meningitis, gonorrhea and infections of the stomach or intestine.

Which medicines should be avoided while taking Closolin 250mg/250mg Capsule?

Closolin 250mg/250mg Capsule should be avoided with methotrexate which is used to treat rheumatoid arthritis, psoriasis and some forms of cancer. This is because combining the two medications can cause some serious side effects.

Related lab tests

Complete Blood Count

Peripheral Smear Examination

Top Physicians

4.5 ★

4.6 ★

4.2 ★

4.1 ★

4.9 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Ampicillin+Cloxacillin. Bangalore, India: Medreich Limited; 2014. [Accessed 08 Apr. 2019] (online) Available from:
ScienceDirect. Cloxacillin. [Accessed 08 Apr. 2019] (online) Available from:
Ampicillin trihydrate. Egham, Surrey: Chemidex Pharma Ltd.; 2005 [revised 8 Apr. 2015]. [Accessed 10 Apr. 2019] (online) Available from:
Drugs.com. Cloxacillin capsules. [Accessed 08 Apr. 2019] (online) Available from:

Marketer details

Name: Osho Pharma Pvt Ltd

Address: Plot No.2404, Phase IV, GIDC Estate, Vatva, Ahmedabad-382445 (Gujarat).

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.