Clothrol 12.5mg Tablet is a diuretic (water pill) medicine used to treat hypertension (high blood pressure). This medicine reduces excess fluid levels in the body and treats edema (fluid overload) associated with heart, liver, kidney, or lung disease.

Clothrol 12.5mg Tablet makes you lose excess water through urine. It may be used alone or in combination with other medicines. This medicine should be taken only during day time to avoid frequent urination at night. You must take this medicine in the dose and duration as advised by the doctor and never stop it abruptly without consulting the doctor. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This may lead to your blood pressure rising again and increase your risk of heart disease and stroke.

It is important to have your blood pressure checked regularly. This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to reduce your salt intake.

Common side effects of this medicine include headache, nausea, and dizziness. Consult your doctor if these side effects bother you. Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult a doctor before taking it. You must inform the doctor about all the other medicines that you are taking apart from this medicine.

Uses of Clothrol Tablet

Benefits of Clothrol Tablet

In Treatment of Hypertension (high blood pressure)

Clothrol 12.5mg Tablet is known as a water pill, which increases urine output thereby lowering blood pressure. If your blood pressure is controlled, you are less at risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly as prescribed to be effective. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well.

In Treatment of Edema

Edema is caused by your body retaining too much water. Clothrol 12.5mg Tablet helps get rid of the extra water and electrolytes from your body by increasing the amount of urine produced. This enables your body to get rid of extra water thereby relieving symptoms such as shortness of breath and swelling in your arms, legs, or abdomen. Therefore, you can carry out your daily activities more comfortably. Take it regularly and make appropriate lifestyle changes to get maximum benefits.

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Side effects of Clothrol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clothrol

Headache
Nausea
Dizziness

How to use Clothrol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clothrol 12.5mg Tablet is to be taken with food.

How Clothrol Tablet works

Clothrol 12.5mg Tablet is a diuretic which lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Safety advice

Alcohol

UNSAFE

Clothrol 12.5mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Clothrol 12.5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CAUTION

Clothrol 12.5mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Its slow clearance may lead to accumulation in the infant.

Driving

UNSAFE

Clothrol 12.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Clothrol 12.5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Clothrol 12.5mg Tablet may be needed. Please consult your doctor.
Use of Clothrol 12.5mg Tablet is not recommended in these patients.

Liver

CAUTION

Clothrol 12.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Clothrol 12.5mg Tablet may be needed. Please consult your doctor.
Use of Clothrol 12.5mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Clothrol Tablet?

If you miss a dose of Clothrol 12.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Clothrol 12.5mg Tablet

₹6.62/Tablet

CTD 12.5 Tablet

Ipca Laboratories Ltd

₹9.67/tablet

46% costlier

New CH 12.5mg Tablet

Systopic Laboratories Pvt Ltd

₹2.5/tablet

62% cheaper

Thaloric 12.5 Tablet

Zuventus Healthcare Ltd

₹8.44/tablet

27% costlier

Chlornol 12.5mg Tablet

Knoll Pharmaceuticals Ltd

₹4.84/tablet

27% cheaper

Lupiclor 12.5 Tablet

Lupin Ltd

₹9.4/tablet

42% costlier

View all substitutes

Quick tips

Take it in the morning with breakfast to avoid getting up at night to urinate.
It makes you feel dizzy. Avoid driving and attention requiring activity until you know how it affects you.
Avoid alcohol intake while taking Clothrol 12.5mg Tablet as it may increase the dizziness.
It may cause a sudden drop of sodium level in blood. Avoid low sodium diet while you are taking this medication.
Monitor your blood pressure after starting Clothrol 12.5mg Tablet, and notify your doctor if it does not lower down.
Notify your doctor if you experience dizziness, tiredness, or muscle weakness that does not go away.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

Thiazide (Related heterocyclics)

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Low-ceiling Diuretics (Inhibitors of Na+Cl symport)

Patient concerns

I am a patient of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinal condition of high blood pressure. Please see a physician.

Some times I had lot of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.

I'm type 2 diabetic patient with hypertension, l am taking following medicines Tezloc 40 - OD Glimisave Max-1 forte. BBF Glimisave Max-2 forte Cd Rozavel -5. Hs My usual blood pressure -80/145 Usual Blood glucose levels :fasting -120 PP-180 Hba1c - 7.6 Pl suggest me whether I need any change in medicines etc. I'm taking Januvia-100 also

Dr. Nabajit Talukdar

Cardiology

seems ok basically need control of blood pressure and hypertension get an ecg n echo done

High blood sugar lavel. Gallstone. High blood pressure

Dr. Sanjay Bhatt

Physician

Need to proper investigate and examine. So plz consult doctor nearby.or you can consult me at snergy multiple speciality clinic RD CITY ,BALJEET COMPLEX NEAR SRS MARKET SECTOR 52 gurgaon 9XXXXXX .Advice to maintain calories intake as per weight ,regular walk or aerobic exercises ,on time take your medicines and once a month visit your diabetologist for routine examination and investigations. Will definitely controlled your sugar and u can live healthy life.

High Sugar, high blood pressure

Dr. Sanjay Bhatt

Physician

FAQs

Can I drink alcohol while taking Clothrol 12.5mg Tablet?

No, do not take alcohol while on treatment with Clothrol 12.5mg Tablet. Taking alcohol with Clothrol 12.5mg Tablet may lower your blood pressure suddenly making you feel dizzy and lightheaded.

What happens if I take more than the recommended dose of Clothrol 12.5mg Tablet?

If you take more than the prescribed dose of Clothrol 12.5mg Tablet, you may experience nausea, lightheadedness, weakness, fast or irregular heartbeat, sleepiness, muscle cramps and pain, difficulty in breathing. Taking this medicine in high doses may even cause a heart attack. In a situation like this, contact your doctor immediately or seek emergency help in a nearby hospital.

Can I take ibuprofen with Clothrol 12.5mg Tablet?

This combination is best avoided since the two medicines may interfere with each other. However, if your doctor advises you to take both ibuprofen and Clothrol 12.5mg Tablet, you will need to keep a regular check on your blood pressure and also monitor your kidney function tests.

Does Clothrol 12.5mg Tablet increase uric acid? Can it cause gout?

Yes, Clothrol 12.5mg Tablet may raise uric acid levels. However, the occurrence of gout due to Clothrol 12.5mg Tablet is very rare.

Does Clothrol 12.5mg Tablet cause skin cancer?

No, there have been no reports of Clothrol 12.5mg Tablet causing skin cancer. However, in rare cases, this medicine can make the skin more sensitive to sunlight than usual. If you are exposed to direct sunlight you may get skin rash, so wear protective clothing and use sunscreen.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 769.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 257.
Opie LH, Krum H, Victor RG, et al. Antihypertensive Therapies. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 241.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 15 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Chlorthalidone. [Accessed 15 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Chlorthalidone. [Updated 2021 Jan 18]. [Accessed 12 Jun, 2023] (online) Available from:

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