Clozane 10 Tablet
Prescription Required
Product introduction
Clozane 10 Tablet is a tricyclic antidepressant. It is used in adults to treat obsessive-compulsive disorder (OCD). It also treats muscular weakness (cataplexy) associated with repeat attacks of sleepiness (narcolepsy) and can manage depression that is unresponsive to other medicines.
Clozane 10 Tablet works by increasing the level of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel sleepy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose will need to be gradually decreased when the doctor decides to stop it.
The most common side effects of this medicine include increased heart rate, blurred vision, and constipation. Initially, this medicine may also cause a sudden drop in the blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not addictive, but you can get extra side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency.
Uses of Clozane Tablet
- Depression
- Anxiety
- Bed-wetting
- Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
- Obsessive-compulsive disorder
- Insomnia
- Neuropathic pain
Benefits of Clozane Tablet
In Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
Narcolepsy is a sleep disorder that causes excessive daytime drowsiness. The affected person may experience excessive sleepiness, sleep paralysis, hallucinations, and in some cases episodes of cataplexy (partial or total loss of muscle control). Clozane 10 Tablet stimulates the brain and makes you fully awake. It also relieves these abnormal symptoms and regulates the sleep cycle. This restores normal sleeping habits and improves your quality of life. You will feel more energetic and will be able to perform better in your daily activities.
Side effects of Clozane Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clozane
- Constipation
- Nausea
- Altered libido
- Dizziness
- Fatigue
- Increased appetite
- Sweating
- Drowsiness
- Urinary incontinence
- Tremors
- Weight gain
- Aggravation of depression
- Agitation
- Anxiety
- Blurred vision
- Delirium (acute confusional state)
- ECG changes
- Headache
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Ringing in ear
- Sleep disorder
- Confusion
- Hallucination
- Mania
- Micturition disorders
- Altered blood sugar level
How to use Clozane Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clozane 10 Tablet is to be taken with food.
How Clozane Tablet works
Clozane 10 Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Clozane 10 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Clozane 10 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Clozane 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Clozane 10 Tablet may cause side effects which could affect your ability to drive.
If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Clozane 10 Tablet, do not drive.
If you feel dizzy, tired, have blurred vision, have difficulty concentrating, or have other effects such as confusion, disorientation or your depression gets worse with Clozane 10 Tablet, do not drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Clozane 10 Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Clozane 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Clozane 10 Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable when you are taking this medicine.
Regular monitoring of liver function tests is advisable when you are taking this medicine.
What if you forget to take Clozane Tablet?
If you miss a dose of Clozane 10 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Quick tips
- It may take 4 to 6 weeks for Clozane 10 Tablet to start working. Keep taking it as prescribed.
- It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Clozane 10 Tablet as it may cause excessive sleepiness.
- Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Fact Box
Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic Antidepressants (TCAs)
Interaction with drugs
Taking Clozane with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm and can be fatal.
Do not consume Moclobemide with Clomipramine. If Moclobemide is essential, ensure a gap of at least 1 day after discontin
Concomitant use may affect heart rhythm and may be fatal. Escitalopram Oxalate may raise blood levels of Clomipramine.
Do not consume Escitalopram Oxalate with Clomipramine.
Concurrent use may cause fatal disturbances in the heart rhythm.
Do not consume Thioridazine with Clomipramine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Amiodarone with Clomipramine.
Concomitant use may affect heart rhythm and may be fatal.
Do not consume Ondansetron with Clomipramine.
Patient concerns
FAQs
Can Clozane 10 Tablet cause impotence?
Yes, Clozane 10 Tablet can cause impotence. Both men and women may experience decreased sexual desire and inability to have an organsm. In males, difficulty in maintaining erection (impotence) or painful ejaculation may be observed. You should consult your doctor immediately if you face any such problems while taking Clozane 10 Tablet.
Is Clozane 10 Tablet safe?
Yes, Clozane 10 Tablet is safe to use if taken in the dose and duration prescribed by the doctor. Clozane 10 Tablet is a medicine that treats Obsessive-Compulsive Disorder (OCD), stabilises mood and behavior. It restores the chemical imbalance in the brain and creates a feeling of well being.
What are the side effects of Clozane 10 Tablet?
Clozane 10 Tablet may cause side effects like difficulty or inability to pass urine, altered libido, constipation, dryness in mouth, ejaculation disorder, indigestion and sleepiness. Please consult your doctor if these side effects worry you. The doctor may suggest ways to treat or prevent them.
What happens if I take an overdose of Clozane 10 Tablet?
If you have taken an overdose of Clozane 10 Tablet, you may experience symptoms such as drowsiness, restlessness, agitation and delirium (disturbed state of mind with restlessness and mental confusion). You may also experience severe sweating, fast heartbeat, feeling of faint, seizures (fits), and you may even go into a state of coma. Immediately consult your doctor and seek medical help if you think you have taken too much of this medicine.
If I am feeling better, can I stop taking Clozane 10 Tablet?
No, do not stop taking Clozane 10 Tablet suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking Clozane 10 Tablet for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Clomipramine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 129-35.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 298-300.
- Clomipramine hydrochloride. Whitby, Ontario, Canada: Patheon Inc.; [revised Jun. 2014]. [Accessed 22 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
- Clomipramine Hydrochlorid [Drug Label]. Hazelwood, MO: Mallinckrodt Inc.; 2007. [Accessed 03 Apr. 2023] (online) Available from:
Marketer details
Name: Cezane Remedies Pvt Ltd
Address: 21, SAHJANAND ESTATE, B/H. LALJI MULJI TRANSPORT, NEAR SANAND CROSS ROAD SARKHEJ- 382210
Country of origin: India
Expires on or after: November, 2026
A licensed vendor partner from your nearest location will deliver Clozane 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: November, 2026
A licensed vendor partner from your nearest location will deliver Clozane 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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