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MBA, MD Pharmacology
Last updated
19 Nov 2024 | 01:02 AM (IST)

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Crizalk 250mg Capsule

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Crizalk 250mg Capsule is used in the treatment of non-small cell lung cancer that is locally advanced or has spread to other areas of the body.

Crizalk 250mg Capsule should be taken with food or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, edema (swelling), and diarrhea are some common side effects of this medicine. Some serious side effects that might occur which need doctor consultation include severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits. Your doctor may perform some blood tests during the treatment to check for liver function.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Crizalk Capsule


Side effects of Crizalk Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Crizalk

  • Dizziness
  • Fatigue
  • Edema (swelling)
  • Decreased appetite
  • Vision disorder
  • Gastrointestinal toxicity
  • Increased transaminase level in blood
  • Upper respiratory tract infection
  • Neuropathy
  • Abnormal blood cell count

How to use Crizalk Capsule

Take this medicine in the dose and duration as advised by your doctor. Crizalk 250mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Crizalk Capsule works

Crizalk 250mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Crizalk 250mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Crizalk 250mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Crizalk 250mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Crizalk 250mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Crizalk 250mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Crizalk 250mg Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Crizalk 250mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Crizalk 250mg Capsule may be needed. Please consult your doctor.
Use of Crizalk 250mg Capsule may not be advised in patients with the severe liver disease.

What if you forget to take Crizalk Capsule?

If you miss a dose of Crizalk 250mg Capsule, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Crizalk 250mg Capsule helps in the treatment of non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
  • Take it at the same time each day, with or without food.
  • Diarrhea, nausea and vomiting may occur with Crizalk 250mg Capsule. Stay hydrated and inform your doctor if it persists.
  • It may cause dizziness or blurring of vision. Don't drive or do anything requiring concentration until you know how it affects you.
  • Inform your doctor if you experience severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
  • Do not take Crizalk 250mg Capsule if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
  • Crizalk 250mg Capsule helps in the treatment of non-small cell lung cancer that is locally advanced, or has spread to other areas of the body.
  • Take it at the same time each day, with or without food.
  • Diarrhea, nausea and vomiting may occur with Crizalk 250mg Capsule. Stay hydrated and inform your doctor if it persists.
  • It may cause dizziness or blurring of vision. Don't drive or do anything requiring concentration until you know how it affects you.
  • Inform your doctor if you experience severe stomach pain, fever, chills, shortness of breath, fast heartbeat, partial or complete loss of vision or changes in bowel habits.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are having treatment with this medicine.
  • Do not take Crizalk 250mg Capsule if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.

Fact Box

Chemical Class
Piperidine and Aminopyridine Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors

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FAQs

How is Crizalk 250mg Capsule administered?

Crizalk 250mg Capsule is generally administered in the form of capsules to be taken orally.

What is Crizalk 250mg Capsule used for?

Crizalk 250mg Capsule is used for treating non small-cell lung cancer caused due to a mutation or defect in a gene called as anaplastic lymphoma kinase in cancer cells in patients who have not responded to previous therapies.

How does Crizalk 250mg Capsule work?

Crizalk 250mg Capsule works by inhibiting an enzyme called as tyrosine kinase that transmits the signal for growth and spread of cancer cells.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 331.
  2. Crizotinib. Dublin, Ireland: Pfizer Ireland Pharmaceuticals; Aug. 2011. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Crizotinib. Bruxelles Belgium: Pfizer Europe; 23 Oct. 2012 [revised Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: India

79341
Inclusive of all taxes
MRP80264  1% OFF
10.0 capsules in 1 strip
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