Culactone 20mg/50mg Tablet is a medicine used in the treatment of congestive heart failure, nephrotic syndrome, ascites associated with liver cirrhosis, and mild and moderate degrees of essential hypertension. It works by reducing the excess fluid levels in the body while maintaining the potassium balance.

It is best to take Culactone 20mg/50mg Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

Common side effects of this medicine include dehydration, dryness of mouth, thirst, weakness, lethargy, muscle pains, and low blood pressure. It might lower down the level of calcium, sodium and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It might cause dizziness or tiredness if happens rise slowly from sitting position or avoid driving.

It is generally safe to use during breastfeeding. Before taking this medicine, tell your doctor if you have any liver or kidney disease or pregnant. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

Uses of Culactone Tablet

Benefits of Culactone Tablet

In Treatment of Ascites associated with Liver cirrhosis

Culactone 20mg/50mg Tablet helps reduce fluid retention and maintains potassium levels while also assisting in reducing fluid retention. This way it helps to address the underlying cause of ascites, manage the symptoms, and maintain electrolyte balance, leading to effective diuresis and improved quality of life for individuals with liver cirrhosis-associated ascites.

In Treatment of Mild and moderate degrees of essential Hypertension (high blood pressure)

If your blood pressure is controlled you are less at risk of having a heart attack or stroke. Culactone 20mg/50mg Tablet reduces the chances of heart diseases and helps you remain healthier for longer. Take it regularly and make appropriate lifestyle changes, such as eating healthy and staying active, to maximize the effectiveness of this medicine.

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Side effects of Culactone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Culactone

Electrolyte imbalance
Volume depletion
Dryness in mouth
Weakness
Lethargy
Restlessness
Muscle pain
Hypotension (low blood pressure)
Fast heart rate
Arrhythmia (irregular heartbeats)
Gastrointestinal disturbance
Feeling thirsty

How to use Culactone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Culactone 20mg/50mg Tablet is to be taken with food.
Avoid Culactone 20mg/50mg Tablet with dietary sodium.

How Culactone Tablet works

Culactone 20mg/50mg Tablet is a combination of two medicines: Furosemide and Spironolactone. Furosemide is a diuretic which removes extra water and certain electrolytes from the body through urine. Over time, it also reduces blood pressure and enables heart to pump efficiently. Spironolactone is also a diuretic which conserves potassium, thereby balancing its levels in the body.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Culactone 20mg/50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Culactone 20mg/50mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Culactone 20mg/50mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Culactone 20mg/50mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Culactone 20mg/50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Culactone 20mg/50mg Tablet may be needed. Please consult your doctor.
Use of Culactone 20mg/50mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Culactone 20mg/50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Culactone 20mg/50mg Tablet may be needed. Please consult your doctor.

What if you forget to take Culactone Tablet?

If you miss a dose of Culactone 20mg/50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Culactone 20mg/50mg Tablet

₹3.74/Tablet

Lasilactone 50 Tablet

Emcure Pharmaceuticals Ltd

₹6.42/tablet

72% costlier

Fruselac Tablet

Lupin Ltd

₹6.19/tablet

66% costlier

Spiromide Tablet

RPG Life Sciences Ltd

₹9.82/tablet

163% costlier

Aldactone F Tablet

RPG Life Sciences Ltd

₹9.82/tablet

163% costlier

Amifru-S Tablet

Torrent Pharmaceuticals Ltd

₹2.7/tablet

28% cheaper

View all substitutes

Quick tips

Culactone 20mg/50mg Tablet helps removes excess water from your body.
Take it in the morning with breakfast to avoid getting up at night to urinate.
It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away.
Your doctor may regularly monitor your blood pressure, kidney function and the level of salts such as potassium and sodium in your blood while you're taking this medication.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Patient concerns

I am a patient of hypertension

Dr. Jyoti Kapoor Madan

Psychiatry

Hypertension is clinal condition of high blood pressure. Please see a physician.

I am liver cirrhosis patient with portal hypertension and swelling in ankles

Dr. Aanchal Maheshwari

Ayurveda

C?se has to be seen in person before starting the treatment

High blood pressure heavy weight

Dr. Pushkar Mani

Physician

reduce weight by exercise & dietfor diet consult dietician for weight loss diet plan chartingfor high BP, tell me ur BP , measure it 2 times daily for 2 days in morning & eveningalso do following blood test before we start any medicationHBA1c, Blood sugar, LIPID profile, LIVER profile, Serum Creatinine, BUN, Uric Acid, Urine routine, CBC

FAQs

What are the recommended storage conditions for Culactone 20mg/50mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

What are the contraindications associated with the use of Culactone 20mg/50mg Tablet?

The use of Culactone 20mg/50mg Tablet should be avoided in patients with hypersensitivity to furosemide, sulfonylureas or spironolactone or any other ingredient of the product. The use of this medicine should also be avoided in patients with anuria, acute renal insufficiency, hepatic coma and pre-coma, low blood pressure (hypotension), cardiac arrhythmias, patients taking aminoglycosides or cephalosporins, kidney dysfunction due to drugs which cause renal damage, patients with high potassium levels (hyperkalemia), Addison's disease and in children with moderate to severe renal impairment.

What is Culactone 20mg/50mg Tablet?

Culactone 20mg/50mg Tablet is a fixed-dose combination of furosemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics and they help to remove excess fluid from the body. The use of this combination is advised in patients of congestive heart failure (heart failure leading to fluid accumulation in the lung and rest of the body), nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (edema) and swelling of the abdomen (ascites).

Is it safe to use Culactone 20mg/50mg Tablet?

Yes, Culactone 20mg/50mg Tablet is safe for most of the patients. However, in some patients it may cause common side effects like dizziness, dehydration, decreased sodium level in blood, breast enlargement in males, decreased magnesium level in blood, decreased calcium level in blood, increased blood uric acid. Inform your doctor if you experience any persistent problem while taking this medicine.

Can the use of Culactone 20mg/50mg Tablet cause dizziness?

Yes, the use of Culactone 20mg/50mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.

Can the use of Culactone 20mg/50mg Tablet cause gout?

Yes, Culactone 20mg/50mg Tablet can cause gout. Culactone 20mg/50mg Tablet contains furosemide which can increase the blood uric acid levels by increasing its absorption from the kidneys. Increased uric acid levels can cause a gout attack. Inform your doctor if you have hyperuricemia (excess of uric acid in blood) or a history of gout before taking this medicine. Use of Culactone 20mg/50mg Tablet should be avoided in patients with gout.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Lactomide. [Accessed 11 Apr. 2019] (online) Available from:
Frusemide and Spironolactone [Patient Information Sheet]. Mehsana, Gujarat: Torrent Pharmaceuticals Ltd. [Accessed 28th Sept. 2023] (online) Available from:

Marketer details

Name: Cubit Healthcare

Address: 1, CUBIT HOUSE, 13/369, Panchratna Estate, B/h Ankoor Oil Factory, Opp. Bhagyoday Hotel, Changodar, Ahmedabad-382210 (Guj.) INDIA.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.