Declare 80mg/250mg Tablet is a combination medicine used in the treatment of abdominal pain. It works effectively to reduce abdominal pain, bloating, discomfort and cramps by relaxing the muscles of the stomach and gut. It also blocks certain chemical messengers that cause pain and discomfort.
Declare 80mg/250mg Tablet is taken with food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are diarrhea, nausea, vomiting, stomach pain, dryness in mouth, loss of appetite, feeling thirsty, and heartburn. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Declare 80mg/250mg Tablet effectively relieves sudden muscle spasms or contractions in the stomach and intestine (gut), thereby relaxing the muscles and improving movement of food. It also blocks chemical messengers in the brain that are responsible for pain sensation. This helps to treat abdominal pain (or stomach pain) as well as cramps, bloating and discomfort. Take Declare 80mg/250mg Tablet as prescribed by the doctor. Eventually, it will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Declare Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Declare
Nausea
Vomiting
Diarrhea
Dryness in mouth
Heartburn
Vertigo
Insomnia (difficulty in sleeping)
Hypotension (low blood pressure)
Fast heart rate
Sweating
Constipation
Increased liver enzymes
Increased white blood cell count (eosinophils)
Decreased white blood cell count (lymphocytes)
Breathlessness
Abdominal pain
Indigestion
Confusion
How to use Declare Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Declare 80mg/250mg Tablet is to be taken with food.
How Declare Tablet works
Declare 80mg/250mg Tablet is a combination of two medicines: Drotaverine and Mefenamic Acid, which relieves abdominal pain and cramps. Drotaverine is an anti-spasmodic medicine which relieves contractions (spasms) associated with smooth muscles in the abdomen. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause abdominal pain and inflammation (swelling).
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Declare 80mg/250mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Declare 80mg/250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Declare 80mg/250mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Declare 80mg/250mg Tablet may cause side effects which could affect your ability to drive. As Declare 80mg/250mg Tablet may cause vertigo.
Kidney
CAUTION
Declare 80mg/250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Declare 80mg/250mg Tablet may be needed. Please consult your doctor. Use of Declare 80mg/250mg Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Declare 80mg/250mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Declare 80mg/250mg Tablet may be needed. Please consult your doctor.
What if you forget to take Declare Tablet?
If you miss a dose of Declare 80mg/250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Last year admitted in Sir Ganga Ram hospital,declare IBS,Now Sleeping issues, ,mind is not constitnt in night,every time is some things, eg.if see cars,bike k No plus karna,suddenly hyper on small-2 things. working in retails.
Dr. Jyoti Kapoor Madan
Psychiatry
These are symptoms of anxiety and obsessive coObsessive compulsive traits with irritability. IBS also is more common in people with anxious personality. You need to consult a psychiatrist for further evaluation and management
Declare 80mg/250mg Tablet is a combination of two medicines: Drotaverine and Mefenamic acid. This medication helps to relieve abdominal pain. Drotaverine relieves muscle spasms associated with smooth muscles in the abdomen. Mefenamic Acid works by blocking the release of certain chemical messengers that cause pain and inflammation (swelling).
Q. Is it safe to use Declare 80mg/250mg Tablet?
Yes, Declare 80mg/250mg Tablet is safe for most of the patients with abdominal pain. However, in some patients it may cause common side effects like nausea, vomiting, heartburn, diarrhoea, loss of appetite, dryness in the mouth, weakness, sleepiness and other uncommon or rare side effects. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.
Q. Can I stop taking Declare 80mg/250mg Tablet when my pain is relieved?
Declare 80mg/250mg Tablet is usually used for short term and can be discontinued when your pain is relieved. However, Declare 80mg/250mg Tablet should be continued if your physician has advised you to do so.
Q. Can the use of Declare 80mg/250mg Tablet cause nausea and vomiting?
Yes, the use of Declare 80mg/250mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Also, avoid taking fatty or fried foods along with the medicine. Talk to your doctor if you have vomiting persists and you notice any signs of dehydration like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting your doctor.
Q. Can the use of Declare 80mg/250mg Tablet cause dry mouth?
Yes, the use of Declare 80mg/250mg Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Avoid spicy, salty and acidic foods (like lemons).
Q. Can I take a higher than the recommended dose of this medicine?
No, do not take a higher than the recommended dose of Declare 80mg/250mg Tablet as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.
Q. What are the recommended storage conditions for Declare 80mg/250mg Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
PubChem. Drotaverine. [Accessed 15 Apr. 2019] (online) Available from:
FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 15 Apr. 2019] (online) Available from:
MedIndia. Drotaverine - Indications, Dosage, Side Effects and Precautions. [Accessed 15 Apr. 2019] (online) Available from:
ScienceDirect. Mefenamic Acid. [Accessed 15 Apr. 2019] (online) Available from:
PACE Hospital. Drotaverine Hydrochloride: Uses, Dose, Side Effects, Indications and Cost. [Accessed 16 Sep. 2024] (online) Available from:
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