Defrijet 250 Tablet is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.

Defrijet 250 Tablet should be taken on an empty stomach. Take it in the exact dose and duration and take it regularly at a fixed time each day to get the maximum benefit from it.

Using of Defrijet 250 Tablet may cause common side effects such as nausea, headache, constipation, and diarrhea. If the side effects persist or worsen, inform your doctor.

Before using this medicine, let your doctor know if you have any kidney or liver diseases. Let your doctor also know about all the other medicines you are taking to ensure your safety.

Uses of Defrijet Tablet

Treatment of Iron overload

Benefits of Defrijet Tablet

In Treatment of Iron overload

Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Defrijet 250 Tablet, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Defrijet 250 Tablet as prescribed by the doctor to get the maximum benefit.

Side effects of Defrijet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Defrijet

Nausea
Headache
Vomiting
Rash
Abdominal pain
Constipation
Itching
Abdominal distension
Diarrhea

How to use Defrijet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defrijet 250 Tablet is to be taken empty stomach.

How Defrijet Tablet works

Defrijet 250 Tablet traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Defrijet 250 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Defrijet 250 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Defrijet 250 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Defrijet 250 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

UNSAFE

Defrijet 250 Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Liver

CAUTION

Defrijet 250 Tablet should be used with caution in patients with liver disease. Dose adjustment of Defrijet 250 Tablet may be needed. Please consult your doctor.

What if you forget to take Defrijet Tablet?

If you miss a dose of Defrijet 250 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Defrijet 250 Tablet

₹23.9/Tablet

Desirox 250mg Tablet

Cipla Ltd

₹34.07/tablet

43% costlier

Deferglob 250mg Tablet

Globela Pharma Pvt Ltd

₹19.4/tablet

19% cheaper

Quick tips

Defrijet 250 Tablet is used to reduce excess iron from the body.
Inform your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
Take an adequate amount of water while taking Defrijet 250 Tablet.
Defrijet 250 Tablet may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
If you are taking any antacid, take them 2 hours before or after Defrijet 250 Tablet.
Inform your doctor if you have any liver or kidney disease.
Inform your doctor if you are pregnant or breastfeeding.

Fact Box

Chemical Class

Triazole & benzoate derivative

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Iron chelating agents

Patient concerns

Hello doctor I have thallassemia major since birth and due to iron overload of repetitive blood transfusion i have diagnosed with diabetes 3 yr ago -at the time of diabetes diagnosis my sugar level is 650 mg/dl. Now according to my case what could be the state of my diabetes type 1 or type 2 ?

Dr. Amit Modi

Paediatrics

Hello, Diabetes in thalassaemia is thought to be caused mainly by iron overload, from repeated blood transfusions, damaging the pancreas. Insulin secretion may be reduced, possibly because iron is directly toxic to the insulin producing pancreatic ?-cells. So it is type 1 DM .

Hello doctor i have thallasemia major since birth and due to iron overload of repetitive blood transfusions from this disease i was diagnosed with diabetes 2 yrs. ago Now my query is can i control my sugar by controlling iron/ferritin?

Dr. Ashwin Porwal

Internal Medicine

No you have to take insulin or Oral hypoglycemic agents for it

Respected mam/sir, Am recently married and I have been suffered from mensus problem and I take treatmnt in homeocare international.Now my problem was cleared.But my hb range is 8.9.Is this range is enough for pregnancy?S baby formation is possible for me?How to increase my hb range? Kindly request you to clear my doubts.Thank you.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Take iron tablets and iron rich diet

User feedback

Patients taking Defrijet 250 Tablet

Once A Day

88%

Twice A Day

Twice A Week

Alternate Day

What are you using Defrijet Tablet for?

Transfusion d*

57%

Iron overload

29%

Others

14%

*Transfusion dependent thalassemia

How much was the improvement?

Average

78%

Excellent

22%

What were the side-effects while using Defrijet 250 Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Defrijet Tablet?

Empty stomach

100%

Please rate Defrijet 250 Tablet on price

Not Expensive

50%

Average

50%

FAQs

What is Defrijet 250 Tablet used for?

Defrijet 250 Tablet is used for removing excess iron from the body due to repeated blood transfusions in patients with beta thalassemia major (a blood disorder)

How does Defrijet 250 Tablet work?

Defrijet 250 Tablet works by binding to excess iron in the blood and removing it from the body through stool.

Related lab tests

Iron Serum

Iron Studies

Total Iron Binding Capacity

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365.
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 6 Apr. 2019] (online) Available from:
Medscaape. Deferasirox. [Accessed 6 Apr. 2019] (online) Available from:
Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
Drugs.com. Deferasirox Pregnancy and Breastfeeding Warnings. [Accessed 6 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:

Marketer details

Name: Sun Pharmaceutical Industries Ltd

Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.