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Defsure 6mg/5ml Suspension

Prescription Required

Your child’s medicine at a glance

Defsure 6mg/5ml Suspension belongs to a group of medicines known as corticosteroids. Its anti-inflammatory and immunosuppressive properties give it the ability to treat a wide range of conditions in children. It is also one of the primary medicines used for Duchenne muscular dystrophy in infants and children.

Give Defsure 6mg/5ml Suspension to your child orally, either before or after food. Giving it with food helps prevent the risk of developing a stomach upset. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.

It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Defsure 6mg/5ml Suspension can suppress your child’s immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child’s doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Defsure 6mg/5ml Suspension can impact both of these.

This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, and fluid and electrolyte disturbance. Reach out to your child’s doctor if these side effects appear.

Let your child’s doctor know if your child is already taking medicines for any type of infection. Also, narrate your child’s complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child’s overall treatment.


Uses of Defsure 6mg/5ml Suspension in children

  • Treatment of Cancer
  • Treatment of Inflammatory conditions
  • Treatment of Autoimmune conditions
  • Treatment of Duchenne muscular dystrophy(DMD)

Benefits of Defsure 6mg/5ml Suspension for your child

In Treatment of Cancer

Defsure 6mg/5ml Suspension helps in the treatment of a variety of cancers, such as leukemia, lymphoma, and multiple myeloma. It works by suppressing the immune system thereby reducing inflammation around the site of cancer. It is used specifically to decrease swelling (edema), associated with tumors of the spine and brain. Moreover, it helps to treat or prevent allergic reactions in cancer patients.

In Treatment of Inflammatory conditions

Defsure 6mg/5ml Suspension gives relief in inflammatory conditions that affect muscles and joints such as arthritis and ankylosing spondylitis. It also helps manage other inflammatory conditions such as asthma, inflammatory bowel disease, uveitis, ulcerative colitis, and allergies. It works by blocking certain chemicals that cause pain and swelling.

In Treatment of Autoimmune conditions

Defsure 6mg/5ml Suspension gives relief in autoimmune conditions like psoriasis, rheumatoid arthritis, eczema, atopic dermatitis, etc. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching, and other allergic-type reactions.

In Treatment of Duchenne muscular dystrophy(DMD)

Duchenne muscular dystrophy (DMD) is a type of muscular dystrophy, characterized by muscle weakness and atrophy due to the effect of the body’s immune system mechanisms. Defsure 6mg/5ml Suspension slows the progression of DMD. The exact mechanism by which it acts is unclear, but it is thought to help mediate the condition by suppressing the immune system. For DMD, Defsure 6mg/5ml Suspension is approved to be used in children above 5 years of age.

Side effects of Defsure 6mg/5ml Suspension in children

Defsure 6mg/5ml Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Defsure

  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Increased appetite
  • Weight gain
  • Frequent urge to urinate
  • Cushing syndrome
  • Cough
  • Abnormal hair growth
  • Upper respiratory tract infection
  • Obesity

How can I give Defsure 6mg/5ml Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Defsure 6mg/5ml Suspension may be taken with or without food, but it is better to take it at a fixed time.
Avoid Defsure 6mg/5ml Suspension with salad and vegetable diet.

How Defsure Suspension works

Defsure 6mg/5ml Suspension is a corticosteroid medicine. It acts like the body’s natural anti-inflammatory hormones called glucocorticoids. Defsure 6mg/5ml Suspension decreases the formation of chemical substances like prostaglandins, leukotrienes, and interleukins that are involved in inflammation, allergy, and cell multiplication. It also suppresses the immune system and stops the immune mechanisms from causing any self-damage to the body.

Safety advice

Kidney
SAFE IF PRESCRIBED
Defsure 6mg/5ml Suspension is safe to use in patients with kidney disease. No dose adjustment of Defsure 6mg/5ml Suspension is recommended.
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defsure 6mg/5ml Suspension to your child.
Liver
CAUTION
Defsure 6mg/5ml Suspension should be used with caution in patients with liver disease. Dose adjustment of Defsure 6mg/5ml Suspension may be needed. Please consult your doctor.

What if I forget to give Defsure 6mg/5ml Suspension to my child?

Do not panic. Unless your child’s doctor has advised a specific regime for your child, give the missed dose as soon as you remember it. Skip the missed dose if it is almost the time for the next dose. Do not give a double dose to catch up and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Defsure 6mg/5ml Suspension
₹62.9/Suspension
Mahacort DZ Suspension
Mankind Pharma Ltd
₹82.48/suspension
27% costlier
Cortimax-XL Suspension
Zuventus Healthcare Ltd
₹174.35/suspension
169% costlier
Eflaza 6mg/5ml Suspension
Solace Biotech Ltd
₹98/suspension
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Defiz Suspension
Lezaa Biotech
₹98/suspension
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Zefcort Suspension
Leeford Healthcare Ltd
₹28.12/suspension
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Quick tips

  • Prefer giving Defsure 6mg/5ml Suspension with food as an empty stomach can trigger acidity and gastric reflux.
  • Avoid giving antacids along with Defsure 6mg/5ml Suspension. If both need to be given, leave a gap of at least 2 hours between administration of Defsure 6mg/5ml Suspension and antacids.
  • Do not give it more often or for longer than advised by your doctor.
  • Defsure 6mg/5ml Suspension can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
  • Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.

Fact Box

Chemical Class
Gluco/mineralocorticoids, progestogins and derivatives
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Glucocorticoids

Interaction with drugs

Taking Defsure with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may disturb the heart rhythm. Your doctor may monitor your potassium levels closely.
Concurrent use may increase the risk of high blood sugar levels. Deflazacort may reduce the efficacy of Gliclazide. Your doctor may monitor your blood glucose levels along with you... More
Concurrent use may disturb the heart rhythm. Your doctor may monitor your potassium levels closely.
Concurrent use may increase the risk of high blood sugar levels. Deflazacort may reduce the efficacy of Glibenclamide. Your doctor may monitor your blood glucose levels along with ... More
Concurrent use may disturb the heart rhythm. Your doctor may monitor your potassium levels closely.

Patient concerns

arrow
Duchenne Muscular Dystrophy & Developmental delay , speech delay
Dr. Gopal Bansilal Samdani
Paediatrics
Your Question is not clear to me . Please ask your question more clearly and in detail and also try be more specific and descriptive.
Babu ke muscular dystrophy genetic problam 48&50gens delite dmd Muscular dystrophy genetic problam medcian pls
Vipul Aggarwal
There are no medcines for It as far as my knowledge is concernedAnd these case are seen by PediatricianPlease let me know if there is any itber way i can help u
arrow

FAQs

Is Defsure 6mg/5ml Suspension a steroid?

Yes, Defsure 6mg/5ml Suspension is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defsure 6mg/5ml Suspension increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).

In what conditions should I avoid giving Defsure 6mg/5ml Suspension to my child?

Avoid giving Defsure 6mg/5ml Suspension to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Defsure 6mg/5ml Suspension should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.

What do I need to know about Defsure 6mg/5ml Suspension and my child’s immunizations?

For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Defsure 6mg/5ml Suspension. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Defsure 6mg/5ml Suspension.

How can I store Defsure 6mg/5ml Suspension at home?

Keep the medicine in a cool dry place out of the reach of children and pets. This will help avoid any accidental intake.

My child is suffering from a seizure disorder. Is it safe to give Defsure 6mg/5ml Suspension to my child?

Ans: Prolonged intake of Defsure 6mg/5ml Suspension can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Defsure 6mg/5ml Suspension.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. University of Michigan: C.S. Mott Children’s Hospital. Deflazacort. [Updated 19 Ju. 2019]. [Accessed 18 Feb. 2021] (online) Available from:External Link
  2. Memorial Sloan Kettering Cancer Center. Deflazacort. [Accessed 18 Feb. 2021] (online) Available from:External Link
  3. Mayo Clinic: Drugs and Supplements. Deflazacort (Oral Route). [Accessed 18 Feb. 2021] (online) Available from:External Link
  4. Emflaza (deflazacort). Frequently asked questions. [Accessed 18 Feb. 2021] (online) Available from:External Link
  5. Deflazacort [Prescribing Information]. Northbrook, IL: Marathon Pharmaceuticals, LLC; 2017. [Accessed 20 Feb. 2024] (online) Available from: External Link

Marketer details

Name: Zuventus Healthcare Ltd
Address: Office No. 5119, 5th Floor, 'D' Wing, Oberoi Garden Estates, Chandivili, Andheri (E), Mumbai - 400 072.
Country of origin: India
Expires on or after: March, 2025

A licensed vendor partner from your nearest location will deliver Defsure 6mg/5ml Suspension. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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