Den-LA 100 Tablet ER is a prescription medicine used in the treatment of depression. This medicine helps by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relaxes the nerves, thus treating your depression.
Den-LA 100 Tablet ER is taken by mouth with or without food. Take it at a fixed time each day to maintain consistent level of medicine in the blood. In case you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as this may worsen your symptoms.
Some common side effects of this medicine includes nausea, vomiting, insomnia (difficulty in sleeping), and constipation. It may cause an increase in blood pressure, especially during the first month of treatment, monitor your blood pressure regularly. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.
Den-LA 100 Tablet ER helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better, and increases your energy levels. Den-LA 100 Tablet ER prevents extreme mood changes and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
Side effects of Den-LA Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Den-LA
Anxiety
Constipation
Decreased appetite
Dizziness
Increased sweating
Insomnia (difficulty in sleeping)
Nausea
Sexual dysfunction
Vomiting
How to use Den-LA Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Den-LA 100 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
How Den-LA Tablet ER works
Den-LA 100 Tablet ER works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Den-LA 100 Tablet ER. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Den-LA 100 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Den-LA 100 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Den-LA 100 Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Den-LA 100 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Den-LA 100 Tablet ER may be needed. Please consult your doctor.
Liver
CAUTION
Den-LA 100 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Den-LA 100 Tablet ER may be needed. Please consult your doctor.
What if you forget to take Den-LA Tablet ER?
If you miss a dose of Den-LA 100 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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How long does it take for Den-LA 100 Tablet ER to work?
The symptoms of depression like change in appetite and sleep patterns may show improvement within 1-2 weeks of starting Den-LA 100 Tablet ER. However, it may take about 5-6 weeks to see the full benefits of Den-LA 100 Tablet ER.
Is Den-LA 100 Tablet ER good for anxiety?
It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.
What time of the day is best to take Den-LA 100 Tablet ER?
Den-LA 100 Tablet ER can be taken either in the morning or in the evening. For best results, take this medicine at the same time each day. This will also help you remember to take it.
Can Den-LA 100 Tablet ER be cut?
Den-LA 100 Tablet ER should be swallowed whole with water. It should not be cut, chewed, crushed or dissolved. Take it exactly as directed by your doctor.
How can Den-LA 100 Tablet ER help treat depression?
Den-LA 100 Tablet ER belongs to a class of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRIs). Serotonin and norepinephrine are chemical messengers in the brain which help maintain mental balance. Den-LA 100 Tablet ER works by increasing the levels of these two hormones in the brain.
Will I gain weight while taking Den-LA 100 Tablet ER?
Weight gain may occur with Den-LA 100 Tablet ER, though not in everyone. In case you notice weight gain after taking Den-LA 100 Tablet ER, consult your doctor or a nutritionist. Take a low calorie food, including more vegetables and fruits in your diet and exercise regularly.
Will Den-LA 100 Tablet ER affect my sex drive?
Taking Den-LA 100 Tablet ER may cause a decrease in sexual desire and ability. It may also cause a delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking Den-LA 100 Tablet ER.
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References
Stahl SM, editor. Desvenlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 175-80.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 375-77.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Desvenlafaxine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from: