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Denip 50 mg/125 mg Syrup

Prescription Required

Your child’s medicine at a glance

Denip 50 mg/125 mg Syrup is a mixture of two medicines. They belong to a class of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDS). Such medicines, including Denip 50 mg/125 mg Syrup, help lower body temperature (fever) and reduce pain and inflammation (redness and swelling) both in infants and children.

Denip 50 mg/125 mg Syrup works by blocking the action of a chemical messenger that is known to cause fever and inflammation. Adhere to the prescribed dose, time, and way while giving this medicine to your child. It can be given orally before or after meals. However, it is best to give this medicine to your child after meals as this will prevent the chance of developing an upset stomach. Try giving it at a fixed time so that it becomes a part of your child’s daily routine and helps prevent missing a dose.

If your child vomits within 30 minutes of taking this medicine, give the same dose again but do skip it if it's time for the next dose. Avoid giving more than the recommended dose for fast relief as that may cause unwanted effects in your child. Complete the full dose of the medicine even if your child feels better after a few doses because stopping the medicine in between may worsen the condition.

Your child may exhibit side effects like nausea, vomiting, stomach pain, heartburn, and diarrhea after taking this medicine. These side effects are temporary and are likely to subside once your child’s body adapts to the medicine. In case they persist or become bothersome for your child, do consult your child’s doctor on a priority basis.


Note: As per the Ministry of Health and Family Welfare, Denip 50 mg/125 mg Syrup is banned for children under 12 years of age.


Uses of Denip 50 mg/125 mg Syrup in children

Benefits of Denip 50 mg/125 mg Syrup for your child

In Pain relief

Denip 50 mg/125 mg Syrup is a combination of two medicines that belong to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Denip 50 mg/125 mg Syrup in children

Denip 50 mg/125 mg Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Denip

  • Allergy
  • Nausea
  • Vomiting
  • Diarrhea
  • Increased liver enzymes

How can I give Denip 50 mg/125 mg Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Denip 50 mg/125 mg Syrup is to be taken with food.

How Denip Syrup works

Denip 50 mg/125 mg Syrup comprises two active ingredients: Nimesulide and Paracetamol. These medicines work by blocking the action of chemical messengers responsible for pain, fever, and inflammation (redness and swelling).

Safety advice

Kidney
CAUTION
Denip 50 mg/125 mg Syrup should be used with caution in patients with kidney disease. Dose adjustment of Denip 50 mg/125 mg Syrup may be needed. Please consult your doctor.
However, the use of Denip 50 mg/125 mg Syrup is not recommended in children with severe kidney disease.
Liver
CAUTION
Denip 50 mg/125 mg Syrup should be used with caution in patients with liver disease. Dose adjustment of Denip 50 mg/125 mg Syrup may be needed. Please consult your doctor.
Discuss with your doctor thoroughly before giving Denip 50 mg/125 mg Syrup to your child. Regular monitoring of Liver Function Tests (LFT) is recommended while your child is taking this medicine.

What if I forget to give Denip 50 mg/125 mg Syrup to my child?

Do not panic. Unless your doctor has advised a specific regime for your child, you may give the missed dose if it’s not more than 12 hours late. If it is almost time for the next dose, do not give a double dose and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Denip 50 mg/125 mg Syrup
₹26.5/Syrup
Nimucet Gold 50mg/125mg Syrup
Intas Pharmaceuticals Ltd
₹12.12/syrup
56% cheaper
Nimucet Syrup
Intas Pharmaceuticals Ltd
₹45/syrup
65% costlier
Biogesic-P 50mg/125mg Syrup
Biochem Pharmaceutical Industries
₹13.75/syrup
50% cheaper
N Mol Syrup
Nippon Seiyaku Pvt Ltd
₹36.7/syrup
34% costlier
Nimotrin P Syrup
Allentis Pharmaceuticals Pvt Ltd
₹32.37/syrup
19% costlier

Quick tips

  • Maintain a log of your child's temperature. If you do not see any improvement, contact your child's doctor for advice.
  • Give plenty of fluids to your child, if diarrhea occurs as a side-effect.
  • If your child exhibits signs of inflammation like redness or swelling,try placing an ice-pack over the affected area to reduce redness and swelling.
  • Never give any other medicine formulation containing paracetamol along with this medicine as that may lead to serious side effects.
  • Stop the medicine and consult your child’s doctor in case your child exhibits allergic rash or stomach pain soon after taking this medicine.
  • If Denip 50 mg/125 mg Syrup does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.

Fact Box

Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Patient concerns

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FAQs

Q. Can I increase or decrease the dose of my child’s medicine by myself?

No, it is not recommended to alter the dose of the medicine without consulting a doctor. While increasing the dose without proper judgment may lead to toxicity, decreasing it may cause recurrence of symptoms. So, for best results, speak to your child’s doctor if you feel a change in dose may be needed.

Q. How much Denip 50 mg/125 mg Syrup should I give to my child?

Your doctor will prescribe the dose according to your child’s condition and body weight. Stick to the prescribed dosing schedule as that is the best way to ensure the safe and complete recovery of your child.

Q. How should Denip 50 mg/125 mg Syrup be stored?

Denip 50 mg/125 mg Syrup should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all medicines out of the reach and sight of children to avoid any accidental intake.

Q. Can all children be given the same dose of Denip 50 mg/125 mg Syrup?

No. Denip 50 mg/125 mg Syrup cannot be given to everyone in the same dose. The doctor decides the appropriate dose of Denip 50 mg/125 mg Syrup based on the child’s age and body weight.

Q. When will my child feel better?

You may be required to give Denip 50 mg/125 mg Syrup to your child for a few days to weeks, depending upon the severity of the infection.If your child continues to feel unwell even after completion of the full prescribed course of the medicine, consult your child’s doctor as soon as possible.

Q. Are there any serious side effects of this medicine for my child?

Although Denip 50 mg/125 mg Syrup is well-tolerated by children, if you notice your child experiencing any intolerable episodes like persistent vomiting, body swelling, decreased urine frequency, or serious allergic reaction, rush to your doctor on an immediate basis.

Q. What is Denip 50 mg/125 mg Syrup?

Denip 50 mg/125 mg Syrup is a combination of two medicines: Nimesulide and Paracetamol. This medication helps in relieving the pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.

Q. Can I stop taking Denip 50 mg/125 mg Syrup when my pain is relieved?

Denip 50 mg/125 mg Syrup is usually used for short-term pain relief and can be discontinued if there is no pain. However, it should be continued if your physician has advised you to do so.

Q. Can the use of Denip 50 mg/125 mg Syrup cause nausea and vomiting?

Yes, the use of Denip 50 mg/125 mg Syrup can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to your doctor if vomiting persists and you notice any signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Q. Are there any specific contraindications associated with the use of Denip 50 mg/125 mg Syrup?

The use of Denip 50 mg/125 mg Syrup is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). Its use should also be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with the history of heart failure, high blood pressure, and liver or kidney disease.

Q. Can I take Denip 50 mg/125 mg Syrup with Vitamin B-complex?

Yes, Denip 50 mg/125 mg Syrup can be taken with Vitamin B-complex preparations. While Denip 50 mg/125 mg Syrup helps to relieve pain, Vitamin B-complex helps to correct the vitamin deficiency that might be causing your symptoms.

Q. Does Denip 50 mg/125 mg Syrup help in relieving stomach pain?

No, Denip 50 mg/125 mg Syrup preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.

Q. Can the use of Denip 50 mg/125 mg Syrup cause damage to the liver?

Denip 50 mg/125 mg Syrup contains Nimesulide and Paracetamol and both these medicines are known to cause harm to the liver especially in the doses above the recommended level. Also, avoid drinking alcohol while taking this medicine, as it may further increase your risk of liver damage. Use of this medicine should preferably be avoided in patients with the underlying liver disease.

Q. Is it safe to take a higher than the recommended dose of Denip 50 mg/125 mg Syrup?

No, you should avoid taking a higher than the recommended dose of Denip 50 mg/125 mg Syrup as it can increase the risks of side effects. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the recommended storage conditions for Denip 50 mg/125 mg Syrup?

Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Nimesulide [Amendments to the Summary of Product Characteristics and Package Leaflet]. [Accessed 10 Feb. 2021] (online) Available from:External Link
  2. Chandra J, Kumar Bhatnagar S. Antipyretics in children. Indian J Pediatr. 2002;69:69-74. [Accessed 10 Feb. 2021] (online) Available from:External Link
  3. National Health Service. Paracetamol for children (including Calpol). [Accessed 10 Feb. 2021] (online) Available from:External Link
  4. Health Navigator, New Zealand. Paracetamol for children. [Accessed 10 Feb. 2021] (online) Available from:External Link
  5. Best Practice e-Journal. Paracetamol dosing for children in primary care. [Accessed 10 Feb. 2021] (online) Available from:External Link
  6. The Royal Children’s Hospital Melbourne. Pain relief for children – paracetamol and ibuprofen. [Reviewed Jul. 2020]. [Accessed 10 Feb. 2021] (online) Available from:External Link

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Address: DIVINE LIFE CARE PVT LTD, 220, MAHAGUJARAT IND. ESTATE AT, PO : MORAIYA, TA : SANAND DIST : AHMEDABAD
Country of origin: India

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