Destab 100mg Tablet ER is a prescription medicine used in the treatment of depression. This medicine helps by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that have a calming effect on the brain and relaxes the nerves, thus treating your depression.
Destab 100mg Tablet ER is taken by mouth with or without food. Take it at a fixed time each day to maintain consistent level of medicine in the blood. In case you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to doctor as this may worsen your symptoms.
Some common side effects of this medicine includes nausea, vomiting, insomnia (difficulty in sleeping), and constipation. It may cause an increase in blood pressure, especially during the first month of treatment, monitor your blood pressure regularly. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Destab
Anxiety
Constipation
Decreased appetite
Dizziness
Increased sweating
Insomnia (difficulty in sleeping)
Nausea
Sexual dysfunction
Vomiting
How to use Destab Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Destab 100mg Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
How Destab Tablet ER works
Destab 100mg Tablet ER works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Destab 100mg Tablet ER. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Destab 100mg Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Destab 100mg Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Destab 100mg Tablet ER may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Destab 100mg Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Destab 100mg Tablet ER may be needed. Please consult your doctor.
Liver
CAUTION
Destab 100mg Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Destab 100mg Tablet ER may be needed. Please consult your doctor.
What if you forget to take Destab Tablet ER?
If you miss a dose of Destab 100mg Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Concomitant use may cause a life-threatening increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and... More
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Concurrent use may cause serotonin syndrome.
watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may d... More
Concomitant use may cause an increase in blood serotonin levels. Patients may experience agitation, increased body temperature, fast heartbeat, muscle rigidity, and loss of coordin... More
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
What are possible physical symptoms of anxiety disorder and depression.
Dr. Subrata Naskar
Psychiatry
Hi PATIENT me clear that for you. Depression is usually associated with a lot of physical symptoms like increased fatigue, decreased amount of sleep or interrupted sleep, loss of appetite usually cause more than 5% body weight loss, loss of libido. But its effect is mainly psychological whivh causes persist low mood, inability to enjoy pleasurable activities, low self esteem, bleak view of the future, guilty feeling etc. These symptoms have to be present persistently for 2 weeks to be called depression. On the other hand, anxiety has two main components, worry and fear. The common physical complaints are extreme sweating, butterfly like feeling in stomach, fidgetiness, increased frequency of urination. If associated with panic attacks, there is often palpitation, respiratory distress, dryness of throat, a sense of doom. Anxiety disorders are of various types and each have varied specific set of symptoms, but these are usually in common.
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
How long does it take for Destab 100mg Tablet ER to work?
The symptoms of depression like change in appetite and sleep patterns may show improvement within 1-2 weeks of starting Destab 100mg Tablet ER. However, it may take about 5-6 weeks to see the full benefits of Destab 100mg Tablet ER.
Is Destab 100mg Tablet ER good for anxiety?
It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.
What time of the day is best to take Destab 100mg Tablet ER?
Destab 100mg Tablet ER can be taken either in the morning or in the evening. For best results, take this medicine at the same time each day. This will also help you remember to take it.
Can Destab 100mg Tablet ER be cut?
Destab 100mg Tablet ER should be swallowed whole with water. It should not be cut, chewed, crushed or dissolved. Take it exactly as directed by your doctor.
How can Destab 100mg Tablet ER help treat depression?
Destab 100mg Tablet ER belongs to a class of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRIs). Serotonin and norepinephrine are chemical messengers in the brain which help maintain mental balance. Destab 100mg Tablet ER works by increasing the levels of these two hormones in the brain.
Will I gain weight while taking Destab 100mg Tablet ER?
Weight gain may occur with Destab 100mg Tablet ER, though not in everyone. In case you notice weight gain after taking Destab 100mg Tablet ER, consult your doctor or a nutritionist. Take a low calorie food, including more vegetables and fruits in your diet and exercise regularly.
Will Destab 100mg Tablet ER affect my sex drive?
Taking Destab 100mg Tablet ER may cause a decrease in sexual desire and ability. It may also cause a delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking Destab 100mg Tablet ER.
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References
Stahl SM, editor. Desvenlafaxine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 175-80.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 375-77.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Desvenlafaxine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from: